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Primary Sleep Disorders 145<br />

suspicion of the disorder. Nocturnal symptoms include snoring, usually with a crescendo<br />

pattern or interruption with snorting or choking noises, witnessed apneas or<br />

pauses in snoring, arousals with choking or dyspnea, motor restlessness and limb<br />

jerking, night sweats, nocturia, gastroesophageal reflux, and dry mouth and drooling.<br />

Daytime symptoms include fatigue, excessive daytime sleepiness, morning<br />

headaches, impaired concentration, decreased libido or impotence, and personality<br />

changes such as irritability. Although patients present with varying combinations<br />

of these symptoms, most of which are very nonspecific, most patients with insomnia<br />

secondary to sleep-disordered breathing will give enough symptoms in a careful<br />

history to raise suspicion of apnea. Accompanying symptoms may be less<br />

prominent in central sleep apnea, but evidence of respiratory failure or underlying<br />

CNS or cardiopulmonary disease may be present.<br />

RLS is characterized by four essential features: (1) a desire to move the limbs<br />

that is usually associated with dysesthesias or paresthesias, (2) motor restlessness,<br />

(3) symptoms that are exclusively present or worsened by rest and relieved at least<br />

partially or temporarily by movement, and (4) a circadian rhythm with symptoms<br />

that are worse in the evening or night, usually near the patient’s habitual bedtime<br />

(39). Additionally, most patients have PLMs during sleep and may have involuntary<br />

limb movements while awake and at rest. Patients with PLMs without RLS<br />

may be unaware of their limb movements. A disheveled bed may provide clues to<br />

movements during sleep.<br />

Narcolepsy is characterized by excessive daytime sleepiness accompanied by<br />

manifestations of dysregulated REM sleep, including cataplexy, hypnogogic hallucinations,<br />

and sleep paralysis (1). Cataplexy is the only symptom that is pathognomonic<br />

for narcolepsy but does not occur in all patients. Patients with nightmares<br />

are aware of vivid dreaming with anxiety-provoking content. Patients with sleep<br />

Case 1: Narcolepsy Presenting with <strong>Insomnia</strong><br />

A 25-year-old man presented with difficulty falling asleep for the past 4<br />

months. Some nights he did not fall asleep until 4 or 5 AM, causing him to be<br />

unable to get up in the morning, causing concentration problems during the<br />

day, and leading him to frequently fall asleep unintentionally in sedentary<br />

situations. The sleepiness affected his life significantly. He had to repeat his<br />

second year of medical school because of frequent episodes of falling asleep<br />

in class and a lack of concentration.<br />

He did not have a regular bedtime. He reported that some nights he went to<br />

bed around 10 PM, some nights 4 AM. Regardless, most nights it took him an<br />

hour or more to fall asleep. Even when he got 8 hours of nighttime sleep, he<br />

still felt tired in the morning. He was as likely to fall asleep during the day<br />

when he got a few hours of sleep as when he got 8 hours of sleep. He did not<br />

take naps routinely, but a couple of times per week he fell asleep studying on<br />

the couch and usually napped for 1 to 3 hours.

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