Epidemiology of <strong>Insomnia</strong> 17 workers tended to be frequent or habitual users of hypnotic medications more than other surveyed occupations (45). Alcohol, unfortunately, is the most commonly used hypnotic among insomniacs (roughly 15% have reported using alcohol in an attempt to self-medicate) (55,71). The underutilization of proper hypnotic medication is also seen among health care providers treating patients with insomnia. From 1987 to 1996, there was a dramatic shift in the United States toward the use of antidepressants in lieu of hypnotics for the symptomatic treatment of insomnia despite a paucity of data regarding their efficacy and the potential for serious side effects (77). Antidepressants and over-the-counter sleep aids remain the most commonly recommended and prescribed treatments for insomnia complaints (77). Statistics available from Scandinavia (Finland, Norway, and Sweden) suggest that benzodiazepines and nonbenzodiazepine hypnotics (zopiclone, zolpidem, and zaleplon), particularly zopiclone, are the hypnotics of choice in those countries (78). ECONOMIC IMPACT OF INSOMNIA <strong>Insomnia</strong> costs the US public $92.5 to $107.5 billion annually, in both direct and indirect expenses including medical expenses, ramifications of accidents, and reduced productivity due to absenteeism and decreased work efficiency (79). In France, it has a similar financial impact. According to a recent study, its direct annual cost (i.e., medical expenses including medications and health care), in 1995, was FF 10,232,992,500 ($2,067,271,100 US) (80). In the same year, Walsh and Engelhardt reported a total direct cost of $13.9 billion in the United States (81). CONCLUSION <strong>Insomnia</strong> is a prevalent complaint in the health care field. It is costly and can cause significant morbidity if not addressed appropriately. Women and the elderly tend to suffer from insomnia more than other groups of the population. Other risk factors include psychosocial stressors, psychiatric and medical problems, low income, unemployment, excessive environmental noise, not having a life partner, job-related stressors, and so on. Patients with insomnia are undertreated and hypnotics are significantly underutilized. Alcohol, unfortunately, remains the most commonly preferred method of self-treatment for insomnia. REFERENCES 1. Mahowald, M. W., Kader, G., and Schenck, C. H. (1997) Clinical categories of sleep disorders I. Continuum 3(4), 35–65. 2. Mellinger, G. D., Balter, M. B., and Uhlenhuth, E. H. (1985) <strong>Insomnia</strong> and its treatment. Prevalence and correlates. Arch. Gen. Psychiatry 42(3), 225–232. 3. Ohayon, M. (1996) Epidemiological study on insomnia in the general population. Sleep 19(3 Suppl), S7–S15. 4. Leger, D., Guilleminault, C., Dreyfus, J. P., Delahaye, C., and Paillard, M. (2000) Prevalence of insomnia in a survey of 12,778 adults in France. J. Sleep Res. 9(1), 35–42.
18 Attarian 5. Sutton, D. A., Moldofsky, H., and Badley, E. M. (2001) <strong>Insomnia</strong> and health problems in Canadians. Sleep 24(6), 665–670. 6. Simen, S., Hajak, G., Schlaf, G., et al. (1995) [Chronification of sleep disorders. Results of a representative survey in West Germany]. Nervenarzt 66(9), 686–695. 7. Ishigooka, J., Suzuki, M., Isawa, S., Muraoka, H., Murasaki, M., and Okawa, M. (1999) Epidemiological study on sleep habits and insomnia of new outpatients visiting general hospitals in Japan. Psychiatry Clin. Neurosci. 53(4), 515–522. 8. Kim, K., Uchiyama, M., Okawa, M., Liu, X., and Ogihara, R. (2000) An epidemiological study of insomnia among the Japanese general population. Sleep 23(1), 41–47. 9. Pallesen, S., Nordhus, I.H., Nielsen, G. H., et al. (2001) Prevalence of insomnia in the adult Norwegian population. Sleep 24(7), 771–779. 10. Husby, R. and Lingjaerde, O. (1990) Prevalence of reported sleeplessness in northern Norway in relation to sex, age and season. Acta Psychiatr. Scand. 81(6), 542–547. 11. Zeitlhofer, J., Rieder, A., Kopfhammer, G., et al.(1994) [Epidemiology of sleep disorders in Austria]. Wien Klin Wochenschr. 106(3), 86–88. 12. Ohayon, M. M. and Hong, S. C. (2002) Prevalence of insomnia and associated factors in South Korea. J. Psychosom. Res. 53(1), 593–600. 13. Lopez, A. T., Sanchez, E. G., and Torres, F.G. (1995) Habitos y trastornos del dormir en residentes del area metropolitana de Monterrey. Salud Mental 18, 14–22. 14. Yeo, B. K., Perera, I. S., Kok, L. P., and Tsui, W. F. (1996) <strong>Insomnia</strong> in the community. Singapore Med. J. 37(3), 282–284. 15. Hyyppa, M. and Kronholm, E. (1987) How does Finland sleep? Sleeping habits of the Finnish adult population and the rehabilitiation of sleep disturbances. Publ. Soc. Ins. Inst. ML(68), 1–110. 16. Dixon, K. N., Monroe, L. J., and Jakim, S. (1981) <strong>Insomnia</strong>c children. Sleep 4(3), 313–318. 17. Archbold, K. H., Pituch, K. J., Panahi, P., and Chervin, R. D. (2002) Symptoms of sleep disturbances among children at two general pediatric clinics. J. Pediatr. 140(1), 97–102. 18. Neveus, T., Cnattinguis, S., Olsson, U., and Hetta, J. (2001) Sleep habits and sleep problems among a community sample of schoolchildren. Acta Paediatr. 90(12), 1450–1455. 19. Liu, X., Sun, Z., Uchiyama, M., Shibui, K., Kim, K., and Okawa, M. (2000) Prevalence and correlates of self-reported sleep problems among Chinese adolescents. Sleep 23(1), 27–34. 20. Ohayon, M. M., Roberts, R. E., Zulley, J., Smirne, S., and Priest, R. G. (2000) Prevalence and patterns of problematic sleep among older adolescents. J. Am. Acad. Child Adolesc. Psychiatry 39(12), 1549–1556. 21. Saarenpaa-Heikkila, O. A., Rintanaka, P. J., Laippala, P. J., and Koivikko, M. J. (1995) Sleep habits and disorders in Finnish schoolchildren. J. Sleep Res. 4(3), 173–182. 22. Tynjala, J., Kannas, L.,and Valimaa, R. (1993) How young Europeans sleep. Health Educ. Res. 8(1), 69–80. 23. Levy, D., Gray-Donald, K., Leech, J., Ziagulis, I., and Pless, I. B. (1986) Sleep patterns and problems in adolescents. J. Adolesc. Health Care 7(6), 386–389. 24. Price, V. A., Coates, T. J., Thoreson, C. E., and Grinstead, O. A. (1978) Prevalence and correlates of poor sleep among adolescents. Am. J. Dis. Child 132(6), 583–586. 25. Kirmil-Gray, K., Eagleston, J., and Gibson, E. (1984) Sleep disturbance in adolescents: sleep quality, sleep habits, beliefs about sleep, and daytime functioning. J. Youth Adolesc. 13, 375–384. 26. Rimpela, A. and Ahlstrom, S. (1983) Health habits among Finnish youth. National Board of Health 71–83. 27. Klink, M. E., Quan, S. F., Kaltenbom, W. T., and Lebowitz, M. D. (1992) Risk factors associated with complaints of insomnia in a general adult population. Influence of previous complaints of insomnia. Arch. Intern. Med. 152(8), 1634–1637. 28. Mitchell, E. S. and Woods, N. F. (1996) Symptom experiences of midlife women: observations from the Seattle Midlife Women’s Health Study. Maturitas 25(1), 1–10. 29. Owens, J. F. and Matthews, K. A. (1998) Sleep disturbance in healthy middle-aged women. Maturitas 30(1), 41–50.
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114 Plotkin months or years. The ef
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152 Duntley 34. Cartwright, R. (197
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188 Index Clonidine, 183 CNS arousa
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190 Index Proton pump inhibitors, 1
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Current Clinical Neurology CLINICAL