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écologie des virus influenza aviaires en Camargue - IRD

écologie des virus influenza aviaires en Camargue - IRD

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Émerg<strong>en</strong>ce du <strong>virus</strong> H5N1 hautem<strong>en</strong>t pathogèneHost structure (e.g. d<strong>en</strong>sity, inter­ and intra­species g<strong>en</strong>etic diversity) differconsiderably betwe<strong>en</strong> wild and domestic birds and is likely to be the maindeterminant of virul<strong>en</strong>ce selection.Virus fitness is highly dep<strong>en</strong>d<strong>en</strong>t on host survival and dispersion in nature, and it isthus unlikely that virul<strong>en</strong>t forms will persist in wild populations if they kill quickly,increase predation risk or compromise migratory performance.Prediction and control of AIV emerg<strong>en</strong>ce urg<strong>en</strong>tly need to consider host ecology andecosystem characteristics (natural or linked with human activities) in which these<strong>virus</strong>es evolve.Competing interestsThe authors declare that they have no competing interests.Authors' contributionsCL reviewed the literature and drafted the manuscript. CJF, FR, FT and MGC revised andimproved the discussion. All authors have read and approved the final manuscript.Acknowledgm<strong>en</strong>tsWe sincerely acknowledge Muriel Dietrich, Thierry Lefèvre and B<strong>en</strong>jamin Roche for theirvaluable comm<strong>en</strong>ts during the preparation of this manuscript. Camille Lebarb<strong>en</strong>chon issupported by a “C<strong>en</strong>tre de Recherches de la Tour du Valat / Région Languedoc­Roussillon”PhD fellowship. This work was funded by the Fr<strong>en</strong>ch “Ag<strong>en</strong>ce Nationale de la Recherche”(ANR) “Santé­Environnem<strong>en</strong>t/Santé au travail”, the “European Union's Framework Program133

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