Breedte geneesmiddelenpakket - Index of

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0.90-0.85 Epilepsy Mild stable angina pectoris (NYHA 1-2) Mental retardation (IQ=70-84) Pneumonia (episode of 2 weeks in an otherwise healthy year) Problem drinking (i.e., some physical, psychological or social problems caused by excessive alcohol intake) Moderate to severe ADL limitations in elderly Young adult in permanent stage after intentionally curative operation for Fallot’s tetralogy or transposition of the great arteries Mild to moderate congenital or early required hearing disorder Mild to moderate agoraphobia Late complications after gonorrhoeal or Chlamydia trachomatis infections (PID, subfertility) Mild to moderate singular phobia Moderate hearing disorder in elderly (i.e., some difficulty to understand or participate in a conversation with one person but great difficulties with conversations with more than one person) Permanent impairmentes after fracture of leg or hip Mild to moderate post traumatic stress disorder Permanent impairmenties after burns Mild depression Osteoarthritis (grade 2) of hip or knee Moderate to severe behavioural disorder (hyperactivity) 0.85-0.80 Young adult in permanent stage after intentionally curative operation for pulmonary stenosis ‘Remnant tuberculosis’ Mild to moderate panic disorder Young adults with a low spina bifida aperta (sacral) Mild to moderate social phobia Permanent locomotor impairment after bacterial meningitis Mild to moderate diffuse anxiety disorder Mild to moderate chronic obstructive pulmonary disease Moderate vision disorder (i.e., great difficulty reading small newspaper print, some difficulty recognizing faces at 4m. distance) Inflammatory bowel disease, in remission Prostate cancer, clinically disease-free after primary therapy Children with permanent impairment after moderate to severe bronchiolitis Hip fracture, rehabilitation phase Diabetes mellitus with neuropathy Non Hodgkin lymphoma of low-grade malignancy, dissemination stage I or II Malignant melanoma I, no evidence of dissemination Prostate cancer, accidentally detected localised prostate cancer, follow-up without active intervention (‘watchful waiting’) Child/adolescent in permanent stage after intentionally curative operation for Fallot’s tetralogy or transposition of the great arteries HIV seropositive Colorectal cancer, clinically disease-free after intentionally curative primary therapy 0.80-0.70 Schizophrenia (one psychotic episode, no permanent impairments) © iMTA, Rotterdam april 2001 90
Symptomatic non-fulminant acute hepatitis B infection Mild rheumatoid arthritis Severe congenital or early acquired hearing disorder Mild to moderate obsessive/compulsive disorder Permanent cognitive impairment after bacterial meningitis Breast cancer, clinically disease-free after the first year Breast cancer, diagnos tic phase and primary therapy for non-invasive breast cancer or tumour < 2 cm Mild dementia (only significant impairment of daily activities) Prostate cancer, diagnostic phase and primary therapy for localised prostate cancer Eating disorders (anorexia nervosa or bulimia nervosa) Diabetes mellitus with nephropathy Lung tuberculosis Mild mental handicap (IQ=50-69) Extrapulmonary tuberculosis 0.70-0.60 AIDS-related complex Compensated liver cirrhosis Multiple sclerosis in ‘relapsing-remitting’ phas e Moderate depression Children with permanent impairments after dysmature birth (‘small for gestational age’, birth weight < 5th percentile) Moderate heart failure (NYHA 3) Patient (10 - 40 jaar) with Down’s syndrome Severe asthma (not symptom-free despite maintenance medication) Children with permanent impairments after perinatal bacterial infection Stroke, mild permanent impairments Chronic hepatitis B infection with active viral replication Oesophageal cancer, clinically disease-free after intentionally curative primarry therapy Moderate rheumatoid arthritis Severe hearing disorder in elderly (i.e., great difficulty or unable to understand or participate in a conversation with one other person) Permanent impairments after mild skull/brain injury Stomach cancer, clinically disease-free after intentionally curative primarry therapy Inflammatory bowel disease, active exacerbation Squamous cell skin carcinoma with lymph node dissemination 0.60-0.50 Severe singular phobia Osteoarthritis (grade 3 - 4) of hip or knee Severe vision disorder (i.e. unable to read small newspaper print, great difficulty or unable to recognize faces at 4m. distance) Colorectal carcinoma, diagnostic phase and primary therapy Malignant melanoma II, lymph node dissemination, no distant dissemination Moderate mental handicap (IQ=35-49) Lung cancer, diagnostic phase and primary therapy for operable non small-cell lung cancer Children with permanent impairments after perinatal viral infection Lung cancer, clinically disease-free after primary therapy for non small-cell lung cancer Initial stage M. Parkinson (initially unilateral, later bilateral tremors and rigidity; slowness, impaired © iMTA, Rotterdam april 2001 91
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Rapport Breedte geneesmiddelenpakke
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Samenvatting Het rapport 'Breedte g
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1. Inleiding Achtergrond Verzoek mi
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vormt voor de huidige beoordelingss
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Advies WRR Generieke beoordelingen
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Eigen rekening en verantwoording Be
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Belangrijkste conclusies iMTA uitma
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3. Toetsing breedte geneesmiddelenp
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Kwantificering therapeutische waard
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Eén geneesmiddel: diverse indicati
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Wetgeving huidig verstrekkingensyst
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4. Conclusies en aanbevelingen 1) H
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9) De mogelijkheden om het criteriu
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Referenties Begeleidingscommissie U
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Colofon Auteurs: Mw. drs. E.A. Stol
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Samenvatting Deze bijlage is een ve
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weten: 1) bij luxe geneeskunde (IVF
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1 Inleiding 1.1 Probleemstelling Op
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De criteria effectiviteit en doelma
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geneesmiddelen werden uitgesloten v
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Het onderzoek naar de vraag hoe uit
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nadere invulling van de criteria en
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Van de twee betekenissen voor noodz
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2.2 Noodzakelijkheid als relatief c
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het mogelijk om nu met kwantitatiev
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Dat de kwaliteit van leven gewichte
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moeten spelen in de prioritering? W
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Aansluitend wordt in stap 3 een ber
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ij hebben, omdat zorg daardoor klan
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vastgesteld op '1' worden uitgeslot
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3 Eigen rekening en verantwoording
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van zorg moeilijk bespreekbaar. Het
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De vraag of een verstrekking voor e
Page 71 and 72: Rokers met een hoog cholesterol heb
Page 73 and 74: 4 Is er een rol voor het lifestyle
Page 75 and 76: 5 Het iMTA model Dit hoofdstuk besc
Page 77 and 78: Het kan worden opgemerkt dat het vo
Page 79 and 80: per QALY geprefereerd boven scenari
Page 81 and 82: huidige besluitvormingsprocedure ge
Page 83 and 84: onderdeel zijn van het doelmatighei
Page 85 and 86: De validiteit van onderzoeksresulta
Page 87 and 88: Neeling, 2000; Berg, in press). Van
Page 89 and 90: waarom het vermijden van inkomensef
Page 91 and 92: onderzoek start 1 juli 2001 en naar
Page 93 and 94: Literatuurlijst Andersson F, Lyttke
Page 95 and 96: Stolk EA, Brouwer WBF, Busschbach J
Page 97 and 98: Bijlage 1 Historisch perspectief In
Page 99 and 100: Maar omdat de grens van noodzakelij
Page 101 and 102: verschillende normatieve keuzen wor
Page 103 and 104: Dunning geïntroduceerd is, waarbij
Page 105 and 106: daarom ook voor de hand om de conse
Page 107 and 108: while others emphasise the need of
Page 109 and 110: Table 2. Example: reimbursement cat
Page 111 and 112: In Australia the Pharmaceutical ben
Page 113 and 114: Figure 2. User charges as source of
Page 115 and 116: which are not? In this way, Germany
Page 117 and 118: 17. Meer, J.v.d., Equal care equal
Page 119 and 120: Voorbeeld 2 Dit voorbeeld beschrijf
Page 121: Bijlage 4 Wegingsfactoren voor ziek
Page 125 and 126: Breast cancer, disseminated Interme
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Breedte geneesmiddelenpakket - Index of

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