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PoPulationand Public HealtH etHics

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policy<br />

the degree of infringement of rights; and it must be demonstrably justified<br />

(scientific evidence should support that these measures are warranted). 4<br />

The Oakes test exposes some of the scientific knowledge necessary to address<br />

the conflict in ethical principles. More explicitly, in the case of mandatory<br />

vaccination, I believe the following scientific questions pertaining to the<br />

problem are particularly salient:<br />

» Is the agent being vaccinated against highly infectious and likely to<br />

spread to patients?<br />

» Can the condition be spread in the asymptomatic phase?<br />

» Are there high levels of morbidity and mortality associated with the<br />

condition being vaccinated against?<br />

» Is there a strong body of evidence for the benefits of the vaccine to<br />

prevent disease in patients?<br />

» Is there evidence that other mechanisms for controlling spread of<br />

the disease do not work.<br />

» Are there minimal harms associated with the vaccine?<br />

» Are there mechanisms in place to provide compensation to individuals<br />

who may be harmed by the vaccine?<br />

The greater number of these questions that can be answered in the affirmative,<br />

the more justifiable the infringements on civil liberties. Conversely, the<br />

greater the numbers of negative answers, the less justifiable are the infringements.<br />

Ultimately, societal values will dictate where along the spectrum of<br />

affirmative and negative responses the decision to allow infringements of<br />

liberty and permit mandatory vaccination is located.<br />

Using this approach to examine the question of mandatory vaccination for influenza<br />

demonstrates that such vaccination is justifiable, although with some<br />

provisos. Influenza is moderately infectious and transmissible to patients and<br />

influenza illness in the elderly can have serious sequelae. Vaccination is moderately<br />

effective in preventing illness and, more importantly, vaccination of<br />

5, 6<br />

health care workers has been demonstrated to prevent illness in patients.<br />

The most serious consequence of vaccination of health-care workers, the development<br />

of Guillain-Barre syndrome, is extremely rare and estimated as a<br />

one in one million risk. 7 Less restrictive measures, such as education programs<br />

PoPulation anD <strong>Public</strong> <strong>HealtH</strong> <strong>etHics</strong><br />

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