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KCE Reports 113 Volume Outcome 101
5.5.3.2 Linkage with data from IMA and BCR
The Minimal Clinical Data (MCD) data were linked with the Common Sickness Funds
Agency (IMA) database and the Belgian Cancer Registry (BCR) database. Table 5.51
shows that 98.1% of 9 633 MCD stays could be linked with IMA data and 87.4% with
BCR data (on the basis of ICD-10 codes C50 and D05). Information on tumour stage
could be retrieved for 79.3% of 9 633 MCD stays.
Table 5.51: Breast cancer surgery: Percentage of linkage of MCD data with
data from IMA and BCR
Number %
Number of stays in MCD selection 9 633
Linkage with IMA 9 450 98.10
Linkage with BCR 8 416 87.37
Linkage with BCR and data about stage 7 643 79.34
Results of linkage: 8 416 patients with breast cancer surgery could be linked
with Belgian Cancer Registry data. For 7 643 of these patients, the BCR
contained information on the stage of the tumour.
5.5.3.3 Patient and tumour characteristics
Tumour location is defined according to ICD-10 code:
• C50 for malignant neoplasm of breast
• D05 for carcinoma in situ of breast.
Tumour histology is not used as a variable for risk adjustment and is therefore not
analyzed in this section. Instead, however, several authors used the tumour
differentiation (also known as grade) for risk adjustment: 221-223
• Grade I : well differentiated
• Grade II : moderately differentiated
• Grade III : poorly differentiated
• Grade IV : undifferentiated
• Unknown differentiation.
For a detailed description of TNM classification and TNM stages for breast cancer, we
224, 225
refer to KCE report 63.
Table 5.52 shows that the mean age of the 9 633 patients selected in the MCD was 60.1
years. Median age is 60.0 years. Carcinoma in situ represents only 8.5% of all patients
operated for breast cancer. Grade II and III are the most represented (34% and 32%,
respectively). 41% of the operated patients have grade 1 breast cancer. Stage 2 disease
comes second with 37.8%.