Het volume van chirurgische ingrepen en de impact ervan op ... - KCE

116 Volume Outcome KCE reports 113
5.6.3.3 Patient and tumour characteristics
The two main histological types are small cell lung cancer and non-small cell lung cancer
(NSCLCa). 108 In accordance with the histological groups defined by the International
Agency for Research on Cancer (IARC) these two types are defined by the following
ICD-O-3 codes: 125
• small cell lung carcinoma: 8041-8045, 8246
• non-small cell lung cancer (NSCLCa) comprises the following groups:
o squamous cell carcinoma: 8050-8078, 8083-8084
o adenocarcinoma: 8140, 8211, 8230-8231, 8250-8260, 8323, 8480-
8490, 8550-8551, 8570-8574, 8576
o large cell carcinoma (include giant cell, clear cell and large cell
undifferentiated carcinoma): 8010-8012, 8014-8031, 8035 and
8310.
A description of TNM classification and TNM stages for lung cancer were described by
Lababede et al. 238
As shown in Table 5.65, mean age of patients was 64.5 years (median is 66 years) and
77% of them were men. The predominant histological type of tumour was non-small cell
lung (88.7%). Out of 902 operated patients with available stage information, more than
half (56%) had stage 0 or 1 lung cancer.
Table 5.65: Lung cancer surgery: Patient and tumour characteristics
Number %
Age (years)
Mean/median 64.5/66.0
Std 10.1
Total 1206
Sex
Male 931 77.2
Female 275 22.8
Total 1206
Tumour histology
Small cell lung carcinoma 23 2.2
Non-small cell lung cancer 934 88.6
Other 97 9.2
Total 1 054
Tumour stage
I 505 56.0
II 185 20.5
III 185 20.5
IV 27 3.0
Total 902