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Het volume van chirurgische ingrepen en de impact ervan op ... - KCE

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200 Volume Outcome <strong>KCE</strong> reports 113<br />

7.2.7.3 Comparative analysis of literature and Belgian data<br />

DEFINITION OF VOLUME<br />

As shown in Table 7.23, Belgian hospitals had a mean annual elective TKR <strong>volume</strong> of 97<br />

in 2004; median is 78; 75 th Perc<strong>en</strong>tile is 120. Table 7.24 shows that Belgian orth<strong>op</strong>aedic<br />

surgeons performed on average 23 elective TKR in 2004; median is 12; 75 th Perc<strong>en</strong>tile is<br />

30 TKR per year. These summary measures are very similar to those for elective total<br />

hip replacem<strong>en</strong>t (see page 49). Wh<strong>en</strong> we compare the highest <strong>volume</strong> hospitals for<br />

elective THR (Figure 5.1) with those for elective TKR (Figure 6.2), the same hospital<br />

IDs turn up on the horizontal axis. This means that Belgian hospitals with a high annual<br />

<strong>volume</strong> of THR, oft<strong>en</strong> also have a high <strong>volume</strong> of elective TKR.<br />

In the selected primary studies and the systematic review, we did not find any<br />

information on the annual TKR <strong>volume</strong> of hospitals or surgeons in other countries.<br />

OUTCOME<br />

Again we have to acknowledge the fact that the Belgian MCD do not capture clinically<br />

rele<strong>van</strong>t outcome measures such as loss of <strong>de</strong>p<strong>en</strong>d<strong>en</strong>ce, loss of mobility or residual<br />

pain.<br />

Table 7.34: Total knee arthr<strong>op</strong>lasty: complication rate: comparison of<br />

Volume-Outcome <strong>KCE</strong> study with sci<strong>en</strong>tific literature<br />

IN-HOSPITAL<br />

<strong>KCE</strong> study Hervey Coyte Kre<strong>de</strong>r Katz<br />

COMPLICATIONS Volume outcome 2003 1999 2003 2004<br />

Complications during in<strong>de</strong>x admission<br />

Death 0.15% 0.21% 0.4%<br />

Deep v<strong>en</strong>ous thrombosis 0.41% 0.48%<br />

Pulmonary embolism 0.46% 0.37%<br />

Deep wound infection 0.06% 0.25%<br />

Complications within 90 days from in<strong>de</strong>x admission<br />

Death 0.5% 0.6%<br />

Deep v<strong>en</strong>ous thrombosis 0.42%<br />

Pulmonary embolism 0.63% 0.8%<br />

Deep wound infection 0.31% 0.4%<br />

AMI 0.20% 0.8%<br />

Pneumonia 0.56% 1.4%<br />

Complications within 1 year (or more) after in<strong>de</strong>x admission<br />

Revision within 1 year 0.98% 0.8%<br />

Revisions within 500 days (1.36<br />

0.2% (*)<br />

year)<br />

1.6% (*)<br />

(*) Coyte et al used two methods to estimate the revision rate: based on a group of pati<strong>en</strong>ts with<br />

the longest time to revision and based on a group with the shortest time.<br />

In-hospital outcome after total knee replacem<strong>en</strong>t<br />

In-hospital outcome in the <strong>KCE</strong> study was first compared with the study by Hervey on<br />

1997 data. 328 See Table 7.34. Hervey’s complication rates were very similar to the ones<br />

that were found in the MCD data except for <strong>de</strong>ep wound infection. This differ<strong>en</strong>ce can<br />

probably be explained by the use of differ<strong>en</strong>t co<strong>de</strong>s. Hervey et al. id<strong>en</strong>tified the<br />

infections by means of ICD-9-CM co<strong>de</strong>s 998.59 “Post<strong>op</strong>erative wound infection” and<br />

686.9 “Post<strong>op</strong>erative wound infection knee (skin)” while we used 996.66 “Infection and<br />

inflammatory reaction due to internal joint prosthesis”. The latter co<strong>de</strong> was an<br />

exclusion criterion in the Hervey study. Kre<strong>de</strong>r et al. reported an in-hospital mortality<br />

of 0.4%, but this is perhaps related to the fact that it concerns ol<strong>de</strong>r data i.e. TKR<br />

performed betwe<strong>en</strong> 1993 and 1996. 329

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