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Het volume van chirurgische ingrepen en de impact ervan op ... - KCE

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<strong>KCE</strong> Reports 113 Volume Outcome 215<br />

b. Evaluation of surgeon <strong>volume</strong> can be performed at short term: in-hospital<br />

mortality, 30-day or 90-day mortality, keeping in mind that evaluating<br />

outcome beyond hospital discharge has the additional ad<strong>van</strong>tage of being<br />

unaffected by differ<strong>en</strong>ces in practice discharges across hospitals. Especially<br />

for low-risk surgical procedures, evaluation of c<strong>en</strong>tre <strong>volume</strong> can require<br />

several years of follow up, because the effect of c<strong>en</strong>tre <strong>volume</strong> is a<br />

mixture of the effect of the surgeon <strong>volume</strong> (the experi<strong>en</strong>ce) and the<br />

effect of organisational aspects of the c<strong>en</strong>tres (such as process indicators,<br />

compliance to gui<strong>de</strong>lines, organization of care), which play a role on a<br />

longer timeframe than surgery skills. To analyze outcomes beyond<br />

hospitalisation, it is necessary to link MCD-MFD data to IMA data. One<br />

shortcoming of these data is that the exact dates (of hospital admission<br />

and of <strong>de</strong>ath) are not available, h<strong>en</strong>ce r<strong>en</strong>ding impossible to evaluate<br />

outcomes at precise time points.<br />

3. It is important to distinguish betwe<strong>en</strong> the effect of the surgeon<br />

<strong>volume</strong> (experi<strong>en</strong>ce) and the effect of the hospital <strong>volume</strong><br />

(organisation of care in the broad s<strong>en</strong>se). The relative importance of<br />

surgeon or hospital <strong>volume</strong> is difficult to distinguish for infrequ<strong>en</strong>t<br />

interv<strong>en</strong>tions where surgeon <strong>volume</strong> equals hospital <strong>volume</strong>. In addition, this<br />

relative importance seems to vary according to the procedure. Two<br />

extremes are carotid <strong>en</strong>darterectomy and lung cancer surgery. CEA, for<br />

example, is technically <strong>de</strong>manding and any failure in surgical practice is<br />

pot<strong>en</strong>tially catastr<strong>op</strong>hic. Other hospital-based services, on the other hand,<br />

are relatively less important i.e. most pati<strong>en</strong>ts un<strong>de</strong>rgoing CEA do not<br />

require int<strong>en</strong>sive post<strong>op</strong>erative managem<strong>en</strong>t. In the case of lung cancer<br />

surgery, in contrast, pati<strong>en</strong>ts rarely die because of direct technical<br />

complications of the procedure itself. Since these pati<strong>en</strong>ts more oft<strong>en</strong> die<br />

from cardiac ev<strong>en</strong>ts, pneumonia and respiratory failure, hospital-based<br />

services are very important. These services inclu<strong>de</strong>, for example, int<strong>en</strong>sive<br />

care, pain managem<strong>en</strong>t, respiratory care and nursing care.<br />

4. Robust information on case mix is important. Pati<strong>en</strong>t characteristics and<br />

disease severity should be available. Risk adjustm<strong>en</strong>t is an important issue in<br />

<strong>volume</strong> outcome research because pati<strong>en</strong>ts with severe co morbidity may be<br />

unequally distributed betwe<strong>en</strong> provi<strong>de</strong>rs of low and high <strong>volume</strong>.<br />

a. MCD data provi<strong>de</strong> information on pati<strong>en</strong>t <strong>de</strong>mographics and co<br />

morbidities. A useful tool is the Charlson score, which has be<strong>en</strong> validated<br />

to predict 1-year mortality. It is a sum of some pre<strong>de</strong>fined weights<br />

attributed to 17 specific conditions. The Charlson score can be computed<br />

based on MCD data, but inherits their limitations i.e. it <strong>de</strong>p<strong>en</strong>ds of the<br />

quality and complet<strong>en</strong>ess of coding of co morbidities in each hospital. The<br />

other drawback of MCD data, the impossibility to differ<strong>en</strong>tiate co<br />

morbidities from complications, has be<strong>en</strong> resolved in MCD since 2008.<br />

b. The other part of the case mix adjustm<strong>en</strong>t, information on disease<br />

severity, is not available in MCD data but can be retrieved in existing<br />

registries, which typically record <strong>de</strong>tailed clinical information.<br />

• With respect to cancer, the Belgian Cancer Registry has <strong>de</strong>tailed<br />

information on tumour characteristics, and the linkage in our study<br />

betwe<strong>en</strong> MCD and BCR data for five conditions was successful. Stage was<br />

still missing in a high pr<strong>op</strong>ortion of cases (on data of 2004), but efforts are<br />

curr<strong>en</strong>tly ma<strong>de</strong> to <strong>en</strong>hance complet<strong>en</strong>ess of stage coding. In future, the<br />

availability of an updated and complete register in combination with the<br />

pati<strong>en</strong>t’s personal id<strong>en</strong>tification number will <strong>en</strong>able complete follow-up of<br />

cancer pati<strong>en</strong>ts in Belgium.

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