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Het volume van chirurgische ingrepen en de impact ervan op ... - KCE

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72 Volume Outcome <strong>KCE</strong> reports 113<br />

Because of lack of reliable short term mortality data, analyses on <strong>volume</strong> outcome<br />

relationship are limited to 2-year mortality. This implies that additional outcome<br />

measures such as post<strong>op</strong>erative bleeding rate and infection rate, which are listed in<br />

Table 2.1 (page 16), are not analyzed in this report.<br />

5.3.6 Volume outcome relationship<br />

5.3.6.1 Analysis by hospital<br />

MORTALITY RATE, BY HOSPITAL<br />

Figure 5.12 pres<strong>en</strong>ts the funnel plot of the number of pancreatectomies per c<strong>en</strong>tre and<br />

the 2-year mortality (observed, i.e. without risk adjustm<strong>en</strong>t). The size of the point is<br />

pr<strong>op</strong>ortional to the number of hospitals with the same <strong>volume</strong> and the same outcome.<br />

The horizontal line repres<strong>en</strong>ts the overall 2-year mortality i.e. 53.2%. One low <strong>volume</strong><br />

c<strong>en</strong>tre is just above the 95% limits of variability, and one medium <strong>volume</strong> c<strong>en</strong>tre has<br />

better performance. None of the hospitals are outliers above the 99.8% limits of<br />

variability, but one medium <strong>volume</strong> hospital shows better outcome (low limits of 95%<br />

variability).<br />

Figure 5.12: Pancreatic cancer surgery: Funnel plot of 2-year mortality rate,<br />

by hospital<br />

DESCRIPTION OF DIFFERENCES IN CHARACTERISTICS ACCORDING TO<br />

THE VOLUME CATEGORY OF THE HOSPITAL<br />

Because the majority of c<strong>en</strong>tres were below the international cut off of 11<br />

interv<strong>en</strong>tions/year, 3 <strong>volume</strong> categories were <strong>de</strong>fined below this cut off and two above.<br />

Table 5.26 shows that 2-year mortality is 65% in very low-<strong>volume</strong> hospitals (1-2<br />

procedures/yr) and less than 50%. in hospitals with at least 6 procedures per annum.<br />

Pati<strong>en</strong>ts who are treated in hospitals with less than 6 interv<strong>en</strong>tions per year are 67<br />

years old while pati<strong>en</strong>ts treated in bigger hospitals are from 63 to 34 years old. The<br />

perc<strong>en</strong>tage of pati<strong>en</strong>ts with Charlson score ≥ 3 is 21% in very low-<strong>volume</strong> hospitals,<br />

compared to 5.6% in the largest hospitals (>20/year). The highest <strong>volume</strong> hospitals<br />

(>20/yr) have <strong>op</strong>erated 25% of pati<strong>en</strong>ts with malignant ne<strong>op</strong>lasm of extrahepatic bile<br />

ducts or ampulla of Vater (which have a better survival rate as se<strong>en</strong> in Table 5.25).

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