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Het volume van chirurgische ingrepen en de impact ervan op ... - KCE

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<strong>KCE</strong> Reports 113 Volume Outcome 177<br />

Table 7.11: Total hip arthr<strong>op</strong>lasty: Differ<strong>en</strong>ces in case-mix and outcomes by<br />

<strong>volume</strong> category of hospital<br />

Tertile based on <strong>volume</strong><br />

≤60 THR > 60 and > 110 THR<br />

≤110 THR<br />

All<br />

Number hospitals 39 38 38 115<br />

Number stays 1327 3248 7281 11856<br />

Male % 42.0 38.0 39.5 39.4<br />

Age<br />

Mean 69.0 68.2 67.1 67.6<br />

Std 11.1 11.3 11.8 11.6<br />

Charlson in<strong>de</strong>x score<br />

Mean 0.6 0.4 0.4 0.4<br />

Std 1.1 1.0 0.9 1.0<br />

Charlson ≥ 3 % 6.8 4.2 3.3 3.9<br />

Principal diagnosis<br />

715 Osteoarthrosis % 86.7 92.3 92.4 91.7<br />

733 Other disor<strong>de</strong>rs of bone & cartilage % 8.4 6.3 6.3 6.6<br />

Other principal diagnosis % 4.8 1.4 1.3 1.7<br />

Severity in<strong>de</strong>x (APR-DRG) for stays with<br />

principal diagnosis 715<br />

1151 2997 6725 10873<br />

1 % 42.9 51.1 52.9 51.3<br />

2 % 42.7 40.8 41.2 41.2<br />

3 % 13.5 7.3 5.3 6.7<br />

4 % 0.9 0.8 0.7 0.7<br />

Complication rate (any) within 90 days % 4.1 4.1 2.9 3.3<br />

Revision rate at 18 months % 1.9 2.3 1.7 1.8<br />

RELATION BETWEEN HOSPITAL VOLUME AND 90-DAY COMPLICATION<br />

(ANY) RATE<br />

The effects from the logistic regression, with the 90-day complication rate as <strong>de</strong>p<strong>en</strong>d<strong>en</strong>t<br />

variable, are pres<strong>en</strong>ted in Table 7.12. Without taking case-mix into account, an increase<br />

of <strong>volume</strong> of 10% is associated with a statistically significant change in the odds of a<br />

complication of -2.62% 95% CI (-4.30%, -0.94%). After adjustm<strong>en</strong>t for the case-mix, the<br />

change is reduced to -1.63% 95% CI (-3.43%, 0.17%) and is not statistically significant<br />

anymore. On the basis of these results, we therefore conclu<strong>de</strong> that, taking case-mix into<br />

account, there is no association betwe<strong>en</strong> the hospital <strong>volume</strong> of THR and the 90-day<br />

complication rate.<br />

Table 7.12: Total hip arthr<strong>op</strong>lasty: Correlation-corrected logistic regression<br />

(GEE) estimates of <strong>de</strong>terminants of 90-day complication<br />

Mo<strong>de</strong>l without adjustm<strong>en</strong>t for case mix Effect 1 95% CI<br />

Hospital <strong>volume</strong> (increase of 10%) -2.62 -4.30 -0.94<br />

Mo<strong>de</strong>l with adjustm<strong>en</strong>t for case mix Effect 1 95% CI<br />

Hospital <strong>volume</strong> (increase of 10%) -1.63 -3.43 0.17<br />

Odds Ratio 95% CI<br />

Sex (male vs. female) 1.05 0.84 1.32<br />

Age (increase of 1 year) 1.02 1.01 1.03<br />

Charlson score (increase of 1 category) 1.48 1.30 1.69<br />

715 vs. other PDX 0.70 0.35 1.39<br />

733 vs. other PDX 1.14 0.57 2.29<br />

1 Effect of 10% increase in <strong>volume</strong> of hospital on the odds of complication within 90 days

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