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Het volume van chirurgische ingrepen en de impact ervan op ... - KCE

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<strong>KCE</strong> Reports 113 Volume Outcome 211<br />

Table 7.44: Hip fracture surgery: Differ<strong>en</strong>ces in case-mix and outcomes by<br />

<strong>volume</strong> category of surgeon<br />

Tertile based on <strong>volume</strong><br />

≤8 > 8 and > 17<br />

≤17<br />

All<br />

Number surgeons 234 225 216 675<br />

Number stays 960 2874 6100 9934<br />

Male % 27.3 24.6 25.2 25.3<br />

Age<br />

Mean 77.8 78.8 79.5 79.2<br />

Std 13.4 12.5 11.7 12.1<br />

Charlson in<strong>de</strong>x score<br />

Mean 1.1 1.2 1.3 1.2<br />

Std 1.6 1.6 1.7 1.7<br />

Charlson ≥ 3 % 15.7 17.2 18.6 17.9<br />

Severity in<strong>de</strong>x<br />

(APR-DRG)<br />

1 % 23.6 23.1 21.8 22.3<br />

2 % 38.3 36.7 39.3 38.5<br />

3 % 30.7 32.6 31.7 31.9<br />

4 % 7.3 7.6 7.2 7.3<br />

In-hospital mortality % 6.8 6.0 6.7 6.5<br />

RELATION<br />

MORTALITY<br />

BETWEEN SURGEON VOLUME AND IN-HOSPITAL<br />

The effects from the logistic regression are pres<strong>en</strong>ted in Table 7.45 for in-hospital<br />

mortality. Without adjustm<strong>en</strong>t for case mix, an increase of 10% of the surgeon had no<br />

significant effect on the in-hospital mortality as the effect was -0.05% (-1.33%, +1.23%).<br />

After adjustm<strong>en</strong>t, the effect is increased but is still not significant at -0.68% (-2.05%,<br />

0.69%). The odds for mortality are doubled in case of male pati<strong>en</strong>t, they are slightly<br />

higher wh<strong>en</strong> age increased by 1 year and they are more than doubled by an increase of<br />

1 category in the Charlson in<strong>de</strong>x score.<br />

Table 7.45: Hip fracture surgery: Correlation-corrected logistic regression<br />

(GEE) estimates of <strong>de</strong>terminants of in-hospital mortality (surgeon <strong>volume</strong>)<br />

Mo<strong>de</strong>l without adjustm<strong>en</strong>t for case mix Effect 1 95% CI<br />

Surgeon <strong>volume</strong> (increase of 10%) -0.05 -1.33 1.23<br />

Mo<strong>de</strong>l with adjustm<strong>en</strong>t for case mix Effect1 95% CI<br />

Surgeon <strong>volume</strong> (increase of 10%) -0.68 -2.05 0.69<br />

Odds Ratio 95% CI<br />

Sex (male vs. female) 1.98 1.65 2.36<br />

Age (increase of 1 year) 1.06 1.05 1.07<br />

Charlson score (increase of 1 category) 2.13 1.98 2.29<br />

1 Effect of 10% increase in <strong>volume</strong> of surgeon on the odds of in-hospital mortality<br />

7.3.7 Discussion<br />

7.3.7.1 External validation of the <strong>de</strong>finition of the procedure<br />

According to the Dutch gui<strong>de</strong>lines on oste<strong>op</strong>orosis from 2002, there would have be<strong>en</strong><br />

15 290 pati<strong>en</strong>ts above 55 years for hip fracture hospitalized in the Netherlands in<br />

1999. 339 Consi<strong>de</strong>ring the number of persons of more than 55 years, if the same<br />

incid<strong>en</strong>ce was observed in Belgium, there would be 12 120 hospitalizations of pati<strong>en</strong>ts<br />

of more than 55 years, which is of course inferior to the 15 230 pati<strong>en</strong>ts hospitalized<br />

for hip fracture id<strong>en</strong>tified by the data extraction, all ages inclu<strong>de</strong>d.

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