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Het volume van chirurgische ingrepen en de impact ervan op ... - KCE

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186 Volume Outcome <strong>KCE</strong> reports 113<br />

Key points on <strong>volume</strong> outcome association for elective total hip<br />

replacem<strong>en</strong>t/arthr<strong>op</strong>lasty (THR)<br />

• A total of 11 856 pati<strong>en</strong>ts were hospitalized in 2004 for a total hip<br />

arthr<strong>op</strong>lasty. Partial arthr<strong>op</strong>lasties, revisions of hip replacem<strong>en</strong>t, bilateral<br />

procedures and procedures for trauma were not inclu<strong>de</strong>d in this selection.<br />

• These interv<strong>en</strong>tions were performed in 115 c<strong>en</strong>tres by 522 surgeons. Annual<br />

mean number of THR was approximately 100 per c<strong>en</strong>tre, and 23 per<br />

surgeon. These <strong>volume</strong>s are much higher than US data (44% of c<strong>en</strong>tres less<br />

than 11 elective THR).<br />

• In-hospital mortality is virtually inexist<strong>en</strong>t after elective THR, and in-hospital<br />

complications are also very rare (or un<strong>de</strong>r reported in the MCD). Following<br />

outcomes were analysed: complications requiring a hospitalisation within 90<br />

days of interv<strong>en</strong>tion (3.3% of all pati<strong>en</strong>ts), and revision of the prosthesis at 18<br />

months (1.8% of all pati<strong>en</strong>ts). Logistic and Cox regression mo<strong>de</strong>ls were fitted<br />

to assess the association betwe<strong>en</strong> these outcomes and hospital or surgeon<br />

<strong>volume</strong>. Factors inclu<strong>de</strong>d in the mo<strong>de</strong>ls were: age, sex, Charlson score and<br />

principal diagnosis (ostheoarthrosis, other disor<strong>de</strong>rs of bone or cartilage, or<br />

other).<br />

• The literature review did not succeed in id<strong>en</strong>tifying good quality systematic<br />

reviews that studied revision rate and 90-day complication rate after THR.<br />

• Complication rate at 90 days was 4.1% for hospitals with less than 110<br />

THR/year, and 2.9 % for other c<strong>en</strong>tres. Results from logistic regression<br />

without adjustm<strong>en</strong>t for case mix showed a statistically significant effect of<br />

hospital <strong>volume</strong> on the probability of complication rate (increase of 10% of<br />

<strong>volume</strong> associated with <strong>de</strong>crease of 2.6% in odds of <strong>de</strong>ath). After adjustm<strong>en</strong>t<br />

for case mix, this effect was reduced (1.6% <strong>de</strong>crease) and was only bor<strong>de</strong>rline<br />

statistically significant.<br />

• The association betwe<strong>en</strong> surgeon <strong>volume</strong> and likelihood of complication at<br />

90 days was more robust: 5.0% for surgeons with ≤ 6 THR/year, 4.5% for<br />

surgeons betwe<strong>en</strong> 6 and 20 THR/yr, and 3.0% for surgeons with more than<br />

20 THR/year. This association remained statistically significant after<br />

adjustm<strong>en</strong>t for case mix.<br />

• Revision rates at 18 months were lowest in high <strong>volume</strong> c<strong>en</strong>tres (1.7% in<br />

c<strong>en</strong>tres with more than 110 THR/year), highest (2.9%) in medium <strong>volume</strong><br />

c<strong>en</strong>tres (betwe<strong>en</strong> 60 and 110 THR) and 1.9% in low <strong>volume</strong> c<strong>en</strong>tres (less<br />

than 60 THR/year). Increases in <strong>volume</strong> were thus not consist<strong>en</strong>tly<br />

associated with <strong>de</strong>creases in revision rate.<br />

• A small <strong>de</strong>crease was observed in revision rates at 18 months from small or<br />

medium <strong>volume</strong> surgeons (≤ 20 THR/year, 2.0%) in comparison with high<br />

<strong>volume</strong> surgeons (> 20 THR/year, 1.8%), but effects are too small to draw<br />

conclusions.<br />

• Unfortunately, the MCD do not provi<strong>de</strong> information on the outcomes of<br />

greatest interest to pati<strong>en</strong>ts such as loss of in<strong>de</strong>p<strong>en</strong>d<strong>en</strong>ce, loss of mobility or<br />

residual pain.<br />

• POSSUM (Physiological and Operative Severity Score for <strong>en</strong>Umeration of<br />

Mortality and morbidity) would be better for risk adjustm<strong>en</strong>t in orth<strong>op</strong>aedic<br />

surgery than the applied Charlson score. However, these clinical parameters<br />

are not <strong>en</strong>co<strong>de</strong>d in the MCD.

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