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94 APPENDICES Physio<strong>the</strong>rapy <strong>KCE</strong> reports vol. B<br />
In <strong>the</strong> more recent Cochrane systematic review, exercise <strong>the</strong>rapy appears to be slightly effective at decreasing pain and<br />
improving function in adults with CLBP, particularly in healthcare populations. Evidence was found of effectiveness in<br />
chronic populations relative to comparisons at all follow-up periods; pooled mean improvement was 7.3 points (95% CI,<br />
3.7 to 10.9) for pain (out of 100), 2.5 points (1.0 to 3.9) for function (out of 100) at earliest follow-up. In studies<br />
investigating patients (i.e. presenting for health care providers) mean improvement was 13.3 (5.5 to 21.1) for pain, 6.9 (2.2<br />
to 11.7) for function, representing significantly greater improvement over studies where participants included those<br />
recruited from a general population (e.g. with advertisements) (Hayden 2005a et 2006).<br />
Limitations of this results may be. The Cochrane review largely reflects limitations of <strong>the</strong> literature, including low quality<br />
studies with heterogeneous outcome measures, inconsistent and poor reporting, and possibility of publication bias (Hayden<br />
2005a et 2006). The ICSI guideline 2005 insists too on <strong>the</strong> point that studies of <strong>the</strong> Cochrane SR 2006 and of <strong>the</strong><br />
NHSCRD HTA report 2000 were limited by inconsistent and poor reporting, publication bias and <strong>the</strong> use of<br />
heterogeneous outcome measures and concludes that exercise <strong>the</strong>rapy provide at best only modest clinical benefits (at<br />
decreasing pain and improving function in adults with chronic low back pain).<br />
There is conflicting evidence for exercise <strong>the</strong>rapy and return to work.<br />
The Philadelphia méta-analysis show no difference on <strong>the</strong> return to work after 1 month (méta-analyse de 3 RCTs de<br />
qualité bonne à moyenne). The CBO 2003 concludes that <strong>the</strong>re is no difference on return to work versus o<strong>the</strong>r<br />
physio<strong>the</strong>rapy treatment. COST B13 2004 concludes that exercise <strong>the</strong>rapy is more effective than GP care on <strong>the</strong> return to<br />
work in at least <strong>the</strong> mid-term (3-6 months) (RCTs de bonne qualité).<br />
The metaanalysis of Kool concluded that <strong>the</strong> qualitative and <strong>the</strong> quantitative analysis showed strong evidence (multiple<br />
relevant, high quality RCTs) that exercises reduces sick days during <strong>the</strong> first follow-up year, <strong>the</strong> effect size was 0.24 (95%<br />
CI 0.36, -0.11). In a subgroup of studies on <strong>the</strong> treatment of severly disabled patients (>90 sick days under usual care) <strong>the</strong><br />
effect size is -0.30 (-0.42, -0.17). The effect size of <strong>the</strong> number of patients receiving a disability allowance was small and not<br />
significant (Kool 2004).<br />
The HTA report of NHS centre for reviews and dissemination (NHS CRD 2000) based on <strong>the</strong> Cochrane systematic<br />
review of van Tulder 2000 conclude that <strong>the</strong>re is strong evidence that exercise <strong>the</strong>rapy may help chronic low back pain<br />
patients return to normal daily activities and work.<br />
Comparison exercise <strong>the</strong>rapy versus o<strong>the</strong>r treatments.<br />
L exercice <strong>the</strong>rapy a la même efficacité que les différentes combinaisons de physiothérapie : ANAES 2000 (17 RCTs de<br />
qualité faible à bonne), CBO 2003 (2 SR de bonne qualité), COST B13 2004 (RCTs de bonne qualité). Level A<br />
L exercice <strong>the</strong>rapy est plus efficace que les GP care habituels (prescription médicamenteuse) : CBO 2003 (SR Van Tulder<br />
1999), COST B13 2004 (RCTs de bonne qualité), que le <strong>the</strong>rmalisme et les exercices à domicile ANAES 2000 (17 RCTs de<br />
qualité faible à bonne).<br />
There is conflicting evidence regarding <strong>the</strong> effectiveness of exercise (outpatient) as compared with intensive multi<br />
disciplinary programmes COST B13 2004 (RCTs de bonne qualité avec résultats contradictoires).<br />
Type d exercices<br />
There is no evidence for an exercise type. As many varied exercise types led to comparable positive effects improvements<br />
it may be hypo<strong>the</strong>sized that reduction of pain an improvement of function is obtained through general and aspecific physical<br />
reconditioning which should be <strong>the</strong> main goal of such programs.<br />
Il n y a pas de forme spécifique d exercice plus efficace qu une autre CBO 2003 (2 SR de bonne qualité Van Tulder 1999,<br />
Hilde 1998). Muscle reconditioning/streng<strong>the</strong>ning exercises is no more effective than o<strong>the</strong>r types of exercise COST B13<br />
2004 (RCTs de bonne qualité). For aerobic exercises versus o<strong>the</strong>r types of exercise, flexion exercises versus o<strong>the</strong>rs types<br />
of exercise, flexion versus extension exercises, <strong>the</strong>re is limited (small number of studies) or conflicting evidence : COST<br />
B13 2004, ANAES 2000.<br />
The Hayden s systematic review (including some poor quality studies) found that individually designed programs including<br />
stretching or streng<strong>the</strong>ning, and is delivered with supervision may improve pain and function.(Hayden 2005 b).<br />
The Liddle s systematic review (including only good or middle quality studies) search to identify what treatment<br />
characteristics are essentials to achieve and maintain successful results. Exercise quality was subsequently assessed<br />
according <strong>the</strong> predominant exercise used. Despite <strong>the</strong> variety offered, exercise has a positive effect on CLBP patients, and<br />
results are largely maintained at follow-up. Streng<strong>the</strong>ning is a common component of exercise programmes, however, <strong>the</strong><br />
role of exercise co-interventions must not be overlooked (Liddle 2004).<br />
According to COST B13 2004, <strong>the</strong>re is moderate evidence that individually supervised exercise <strong>the</strong>rapy is not more<br />
effective than supervised groups exercises (one low quality RCT N=190 and one high quality RCT N=148).<br />
Duration of <strong>the</strong> exercise <strong>the</strong>rapy<br />
Le rapport HTA du Centre for Clinical Effectiveness (Jackson 2002) se base sur la Cochrane systematic review (van Tulder<br />
2002) et 8 RCTs de bonne qualité méthodologique. It conclude that 1) A 3-month program of gym workouts was shown<br />
to reduce pain and improve spinal and muscle flexibility significantly more than a home exercise program ; 2) A 3-month<br />
program of muscle reconditioning using training devices was equally effective as physio<strong>the</strong>rapy or aerobics in reducing pain