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Microscopic examination (patients A,C &D,fig. 3). All tumors were well vascularized and
highly cellular, with nuclear polymorphism, several mitoses and irregular amounts of
cytoplasm. Immunohistochemistry was positive for GFAP, EMA, NSE, S-100, LEU-?,
LCA, vimentin and 0i1antitrypsin, and negative for several other labels. In patient C some
cells were arranged in ribbons, and rosettes and microcystic spaces were found. In patient
D typical tubuli and some necrosis were present. Electronmicroscopy of this tumor showed
a uniform population of cells, with well developed rough endoplasmatic reticulum and Golgicomplex.
Desmosomal structures and interdigitating villi were seen frequently.
A
B
c
Figure 3,
Histopathology, hematoxylin and eosin stain. A, patient A (obj 25X), B, patient B (obj 25X). C,
patient D (obj 40X).
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