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9 22 39 41 51 121140144 22q· 4p+ 22q+
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5.D22$1 @ ® 0 - 0
6.022$193 @0@®.00® 0 - 0
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cos40D2" 0 - 0
cos58B12*
•
0 0
cos 50811* 000
cos 76A4* 0 - 00
7. co, 2985' (022S72) - 0 -
S. co, 103012'(022S56) - 0 -
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14. D22$105 e> 0
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LOH 0: noLOH ('): not Informative no circle: no data
0, present on marker - : not present on marker
Figure 2.
Schematic representation of deletions of chromosome 22q. The localization of the different
markers on 22q with their most likely order are indicated (see methods). Markers with asterisks
(*) were used for FISH and all the others for Southern blot analysis (figure I). For meningioma
J2 we investigated hoth hybrid cell lines segregating the 22q- and the 4p+ derivative
chromosomes respectively and cultured tumor 32 cells using FISH and Southern blotting.
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