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New Zealand Autism Spectrum Disorder Guideline - Ministry of Health

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Generic name Trade name NZ prescribing information Recommended dose range Adverse effects Important interactions<br />

Other drugs<br />

Clonidine<br />

Catapres<br />

Dixarit<br />

Tablet: 25mcg (Dixarit); 150mcg<br />

(Catapres)<br />

Transdermal systems: 100mcg,<br />

200mcg and 300mcg per day<br />

Retail pharmacy<br />

Fully subsidised<br />

2 to 5 micrograms/kg/day<br />

Start with once daily dose. Twice<br />

daily as dose increased<br />

• Sedation<br />

• Hypotension (Monitor blood<br />

pressure)<br />

• Depression<br />

• Withdrawal hypertension (taper<br />

over 6 days)<br />

Previous concerns about<br />

interaction with Methylphenidate<br />

have not been proven.<br />

• Precocious puberty – rare<br />

Benztropine<br />

Benztrop<br />

Tablet: 2mg (Benztrop)<br />

0.02 to 0.03 mg/kg/dose • Sedation<br />

Used to treat EPSE.<br />

Cogentin<br />

Also injection (Cogentin)<br />

• Headache<br />

Retail pharmacy<br />

• Nausea<br />

Fully subsidised<br />

• Confusion<br />

Trimeprazine Vallergan Oral liquid: 30mg/5ml<br />

<strong>New</strong> <strong>Zealand</strong> <strong>Autism</strong> <strong>Spectrum</strong> <strong>Disorder</strong> <strong>Guideline</strong> 305<br />

Promethazine<br />

Melatonin<br />

Appendices<br />

Phenergan<br />

Avomine<br />

Allersoothe<br />

Retail pharmacy<br />

Partial subsidy<br />

Oral liquid: 5mg/5ml<br />

Tablet: 10mg; 25mg<br />

Retail pharmacy<br />

Part subsidy on liquid<br />

Fully subsidised tablet formulations<br />

Not funded in <strong>New</strong> <strong>Zealand</strong>. A<br />

range <strong>of</strong> formulations is available<br />

from retail pharmacies.<br />

NOTE: Information is correct at time <strong>of</strong> writing. Brands available and subsidy status are under constant review. Prescribers should check current information on the<br />

PHARMAC (www.pharmac.govt.nz) and MEDSAFE (www.medsafe.govt.nz) websites.<br />

Appendices

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