trans

INDEX 477
Mosquito vectors, 26
MSPL, 79
Mucins:
RNA post-transcriptional regulation, 79
see also Surface mucins
Multidrug-resistance (MDR), 402
see also P-glycoprotein
Muscle cells, Ascaris, 362–4
arm, 363–4
membrane potential, 365–6
muscle bag, 363
spindle, 362–3
Na -dependent glucose transporter (SGLT), 300
Na /K -ATPase:
cestodes, 301
nematodes, 332
trematodes, 306
NAD-specific aldehyde/alcohol dehydrogenase,
130
NADH:rhodoquinone oxidoreductase, 347
NADH dehydrogenase, 161, 163
Nanophyetus salmincola, 458
Napthalophos, 367
Necator americanus, 455
genome, 23
Nematodes, 311–37, 438
alimentary tract, 311, 328–9
defecation, 334–5
digestive processes, 329–30
drug targeting, 335
intestinal protein vaccine targets, 335–6
amino acid catabolism, 183
anhydrobiotic survival, 321
trehalose metabolism, 323
aqueporins, 322, 326
bombesin-like neuropeptides, 320–1
chemotherapy:
filarial disease, 457–8
intestinal worms, 455–7
cuticle, 297, 311, 312–28
biochemistry/molecular biology, 314–16
developmental biology, 316
epicuticle, 312–13, 314
functions, 317–28
hypodermis, 314, 315
structure, 312–14
drug metabolism:
absorption, 326–7
P-glycoproteins, 333–4
energy metabolism, 324
environmental challenges, 311, 312
excretion, 323–6, 333
H , 324–5
organic acids, 324, 325, 327, 333
expressed sequence tag (EST) datasets, 9
filarial reference strains, 13
genomics, 4, 5, 20, 22–5
karyotyping, 7
mitochondrial, 25
hydrostatic skeleton, 317, 321
immune evasion, 327–8
inorganic ion transport, 318–21, 332–3
internal surfaces, 328–36
anatomy, 328–9
biochemistry/molecular biology, 329
functions, 329–36
movement, 317, 321
neurotransmitters, 366–84
nutrient absorption, 318, 330
osmoregulation, 321–3, 330–2, 336–7
proteinase inhibitors, 179
proteolytic enzymes, 178–9
pseudocoelom internal pressure, 317,
318, 321
purine/pyrimidine metabolism, 206–7,
222
RNA trans-splicing, 30, 31, 33
biological function, 37
sex chromosomes, 24–5
somatic chromosome diminution, 23
species/stage-dependent adaptations,
311–12
transcription, 47, 48
polycistronic, 49
protein coding genes, 49, 59
spliced leader (SL) RNA genes, 59
tubular system, 311, 328, 336–7
NEO, 418
Neurotransmitters, 359–93
nematodes, 366–84
platyhelminths, 384–92
New permeation pathway, 157, 160, 201
nhr-23, 316
Nifurtimox, 414, 422, 432, 446, 447
resistance, 423
Nippostrongylus brasiliensis:
amino acid catabolism, 183
digestive processes, 329
energy metabolism, 352, 353
excretion, 326
pyrimidine metabolism, 222