BNF for Children 2011-2012

BNFC 2011–2012 6.1.2 Antidiabetic drugs 357Injection devicesAutopen c (Owen Mumford)Injection device; Autopen c 24 (for use with Sanofi-Aventis3-mL insulin cartridges), allowing 1-unit dosage adjustment,max. 21 units (single-unit version) or 2 unit dosage adjustment,max. 42 units (2 unit version), net price (both) =£15.73; Autopen c Classic (for use with Lilly and Wockhardt3-mL insulin cartridges), allowing 1-unit dosage adjustment,max. 21 units (single-unit version) or 2 unit dosage adjustment,max. 42 units (2-unit version), net price (all) = £15.97ClikSTAR c (Sanofi-Aventis)Injection device, for use with Lantus c , Apidra c , andInsuman c 3-mL insulin cartridges; allowing 1-unit doseadjustment, max. 80 units, net price = £25.00HumaPen c Luxura (Lilly)Injection device, for use with Humulin c and Humalog c 3-mL cartridges; allowing 1-unit dosage adjustment, max.60 units, net price = £26.36HumaPen c Luxura HD (Lilly)Injection device, for use with Humulin c and Humalog c 3-mL cartridges; allowing 0.5-unit dosage adjustment, max.30 units, net price = £26.36NovoPen c (Novo Nordisk)Injection device; for use with Penfill c insulin cartridges;NovoPen c Junior (for 3-mL cartridges), allowing 0.5-unitdosage adjustment, max. 35 units, net price = £24.79;NovoPen c 3 Demi (for 3-mL cartridges), allowing 0.5-unitdosage adjustment, max. 35 units, net price = £25.21;NovoPen c 4 (for 3-mL cartridges), allowing 1-unit dosageadjustment, max. 60 units, net price = £26.56OptiClik c (Sanofi-Aventis)Injection device, for use with Lantus OptiClik c or ApidraOptiClik c insulin cartridges, allowing 1-unit dosage adjustment,max. 80 units, net price = £20.13OptiPen c Pro 1 (Sanofi-Aventis)Injection device, for use with Insuman c insulin cartridges;allowing 1-unit dosage adjustment, max. 60 units, net price =£22.00LancetsLancets—sterile, single use (Drug Tariff)BD Micro-Fine c + 100 = £3.16, 200 = £6.13; CareSens c 100= £2.95; Cleanlet Fine c 100 = £3.19, 200 = £6.13; Fastclix c204 = £9.20; 1 Finepoint c 100 = £3.54; 1 FreeStyle c 200 =£7.02; 1 Microlet c (formerly Ascenscia Microlet c ) 100 =£3.76, 200 = £7.17; 1 Milward Steri-Let c , 23 gauge, 100 =£3.00, 200 = £5.70, 28 gauge, 100 = £3.00, 200 = £5.70;1 Monolet c 100 = £3.28, 200 = £6.24; Monolet c Extra 100 =£3.28; MPD Ultra Thin c , 100 = £3.30, 200 = £6.50;Multiclix c 204 = £9.27; One Touch Comfort c 200 = £7.22;1 One Touch UltraSoft c 100 = £3.61; 2 Softclix c 200 = £7.40;2 Softclix XL c 50 = £1.85; Thin Lancets, 200 = £7.16; 1 UniletComforTouch c 100 = £3.60, 200 = £6.83; Unilet Eco c 100 =£2.94, 200 = £5.49; 1 Unilet General Purpose Superlite c 100= £3.67, 200 = £6.96; Unistik 3 Comfort c , 28-gauge, 100 =£6.24, 200 = £12.20; Unistik 3 Extra c , 21-gauge, 100 = £6.24,200 = £12.20; Unistik 3 Normal c , 23-gauge, 100 = £6.24,200 = £12.20; Universal c , 200 = £6.37; Vitrex Soft c , 23-gauge, 100 = £3.00, 200 = £5.70; Vitrex Gentle c 28-gauge,100 = £3.19, 200 = £6.13; WaveSense Ultra-Thin c 28-gauge,200 = £6.90, 33-gauge, 200 = £6.90Compatible finger-pricking devices (unless indicated otherwise,see footnotes), all D: B-D Optimus c , Glucolet c , Monojector c ,Penlet II c , Soft Touch c1. D Autolet c and D Autolet Impression c are alsocompatible finger-pricking devices2. Use D Softclix c finger-pricking deviceNeedlesHypodermic Needle, Sterile single use (Drug Tariff)For use with reusable glass syringe, sizes 0.5 mm (25G),0.45 mm (26G), 0.4 mm (27G). Net price 100-needle pack =£2.74Brands include Microlance c , Monoject cNeedles for Prefilled and Reusable Pen Injectors (DrugTariff)Screw on, needle length 6.1 mm or less, net price 100-needlepack = £12.53; 6.2–9.9 mm, 100-needle pack = £8.89; 10 mmor more, 100-needle pack = £8.89Brands include BD Micro-Fine c +, Comfort Point c , NovoFine c ,Novofine Autocover c , NovoTwist c , Unifine c PentipsSnap on, needle length 6.1 mm or less, net price 100-needlepack = £12.02; 6.2–9.9 mm, 100-needle pack = £8.52; 10 mmor more, 100-needle pack = £8.52Brands include Penfine cSyringesHypodermic Syringe (Drug Tariff)Calibrated glass with Luer taper conical fitting, for use withU100 insulin. Net price 0.5 mL and 1 mL = £9.22Brands include Abcare cPre-Set U100 Insulin Syringe (Drug Tariff)Calibrated glass with Luer taper conical fitting, supplied withdosage chart and strong box, for blind patients. Net price1 mL = £21.99U100 Insulin Syringe with Needle (Drug Tariff)Disposable with fixed or separate needle for single use orsingle patient-use, colour coded orange. Needle length 8 mm,diameters 0.33 mm (29G), 0.3 mm (30G), net price 10 (withneedle), 0.3 mL = £1.38, 0.5 mL = £1.33; needle length12 mm, diameters 0.45 mm (26G), 0.4 mm (27G), 0.36 mm(28G), 0.33 mm (29G), net price 10 (with needle), 0.3 mL =£1.45; 0.5 mL = £1.43; 1 mL = £1.44Brands include BD Micro-Fine c +, Clinipak c , Insupak c , Monojectc Ultra, Omnikan c , Plastipak cAccessoriesNeedle Clipping (Chopping) Device (Drug Tariff)Consisting of a clipper to remove needle from its hub andcontainer from which cut-off needles cannot be retrieved;designed to hold 1200 needles, not suitable for use withlancets. Net price = £1.35Brands include BD Safe-Clip cSharpsguard (Drug Tariff)Net price 1-litre sharpsbin = 85p6.1.2 Antidiabetic drugs6.1.2.1 Sulfonylureas6.1.2.2 Biguanides6.1.2.3 Other antidiabetic drugsOral antidiabetic drugs are used for the treatment oftype 2 diabetes mellitus. They should be prescribed onlyif the child fails to respond adequately to restriction ofenergy and carbohydrate intake and an increase inphysical activity. They should be used to augment theeffect of diet and exercise, and not to replace them.In children, type 2 diabetes does not usually occur untiladolescence and information on the use of oral antidiabeticdrugs in children is limited. Treatment with oralantidiabetic drugs should be initiated under specialistsupervision only; the initial dose should be at the lower6 Endocrine system