BNF for Children 2011-2012

BNFC 2011–2012 1.1.1 Antacids and simeticone 37Indication and doseDyspepsia for dose see preparationsHyperphosphataemia section 9.5.2.2Co-magaldroxCo-magaldrox is a mixture of aluminium hydroxide andmagnesium hydroxide; the proportions are expressed in theform x/y where x and y are the strengths in milligrams per unitdose of magnesium hydroxide and aluminium hydroxiderespectivelyMaalox c (Sanofi-Aventis)Suspension, sugar-free, co-magaldrox 195/220(magnesium hydroxide 195 mg, dried aluminiumhydroxide 220 mg/5 mL (low Na + )). Net price 500 mL= £2.79Dose. By mouthChild 14–18 years 10–20 mL 20–60 minutes after mealsand at bedtime, or when requiredMucogel c (Chemidex)Suspension, sugar-free, co-magaldrox 195/220(magnesium hydroxide 195 mg, dried aluminiumhydroxide 220 mg/5 mL (low Na + )). Net price 500 mL= £1.71Dose. By mouthChild 12–18 years 10–20 mL 3 times daily, 20–60 minutesafter meals and at bedtime, or when requiredMAGNESIUM TRISILICATECautions heart failure, hypertension; metabolic orrespiratory alkalosis, hypermagnesaemia; interactions:Appendix 1 (antacids)Contra-indications severe renal failure; hypophosphataemiaHepatic impairment see notes aboveRenal impairment see notes above; magnesium trisilicatemixture has a high sodium contentSide-effects see notes above; silica-based renalstones reported on long-term treatmentIndication and doseDyspepsia for dose see under preparationMagnesium Trisilicate Mixture, BP(Magnesium Trisilicate Oral Suspension)Oral suspension, 5% each of magnesium trisilicate,light magnesium carbonate, and sodium bicarbonatein a suitable vehicle with a peppermint flavour. Containsabout 6 mmol Na + /10 mLDose. By mouthChild 5–12 years 5–10 mL with water 3 times daily or asrequiredChild 12–18 years 10–20 mL with water 3 times daily oras requiredAluminium-magnesium complexesHYDROTALCITEAluminium magnesium carbonate hydroxidehydrateCautions see notes above; interactions: Appendix 1(antacids)Hepatic impairment see notes aboveRenal impairment see notes aboveSide-effects see notes aboveIndication and doseDyspepsia for dose see under preparationWith simeticoneAltacite Plus csee belowAntacid preparations containingsimeticoneAltacite Plus c (Peckforton)Suspension, sugar-free, co-simalcite 125/500 (simeticone125 mg, hydrotalcite 500 mg)/5 mL (low Na + ).Net price 500 mL = £2.79Dose. By mouthChild 8–12 years 5 mL 4 times daily (between meals andat bedtime) when requiredChild 12–18 years 10 mL 4 times daily (between mealsand at bedtime) when requiredAsilone c (Thornton & Ross)Suspension, sugar-free, dried aluminium hydroxide420 mg, simeticone 135 mg, light magnesium oxide70 mg/5 mL (low Na + ). Net price 500 mL = £1.95Dose. By mouthChild 12–18 years 5–10 mL after meals and at bedtimeor when required up to 4 times dailyMaalox Plus c (Sanofi-Aventis)Suspension, sugar-free, dried aluminium hydroxide220 mg, simeticone 25 mg, magnesium hydroxide195 mg/5 mL (low Na + ). Net price 500 mL = £2.79Dose. By mouthChild 2–5 years 5 mL 3 times dailyChild 5–12 years 5–10 mL 3–4 times dailyChild 12–18 years 5–10 mL 4 times daily (after mealsand at bedtime) or when requiredSimeticone aloneSIMETICONEActivated dimeticoneIndication and doseColic or wind pain for dose see under individualpreparations1 Gastro-intestinal system