BNF for Children 2011-2012

BNFC 2011–2012 13.10.2 Antifungal preparations 589Indication and doseFungal nail infectionsApply to infected nails 1–2 times weekly after filingand cleansing; allow to dry (approx. 3 minutes);treat finger nails for 6 months, toe nails for 9–12months (review at intervals of 3 months); avoid nailvarnish or artificial nails during treatmentLoceryl c (Galderma) ANail lacquer, amorolfine (as hydrochloride) 5%, netprice 5-mL pack (with nail files, spatulas, and cleansingswabs) = £18.17. Label: 10, patient informationleafletExcipients none as listed in section 13.1.3BENZOIC ACIDLicensed use licensed for use in children (age rangenot specified by manufacturer)Indication and doseRingworm (tinea) but see notes above; dose underpreparationWith salicylic acidFor prescribing information on salicylic acid, seep. 571Benzoic Acid Ointment, Compound, BP(Whitfield’s ointment)Ointment, benzoic acid 6%, salicylic acid 3%, inemulsifying ointmentExcipients include cetostearyl alcoholDoseChild 1 month–18 years apply twice dailyCLOTRIMAZOLECautions see notes abovePregnancy minimal absorption from skin; not knownto be harmfulSide-effects see notes aboveLicensed use licensed for use in children (age rangenot specified by manufacturer)Indication and doseFungal skin infectionsApply 2–3 times dailyVaginal candidiasis section 7.2.2Otitis externa section 12.1.1Clotrimazole (Non-proprietary)Cream, clotrimazole 1%, net price 20 g = £1.52Canesten c (Bayer Consumer Care)Cream, clotrimazole 1%, net price 20 g = £2.14, 50 g =£3.50Excipients include benzyl alcohol, cetostearyl alcohol, polysorbate 60Solution, clotrimazole 1% in macrogol 400 (polyethyleneglycol 400), net price 20 mL = £2.43. Forhairy areasExcipients none as listed in section 13.1.3Spray, clotrimazole 1%, in 30% isopropyl alcohol, netprice 40-mL atomiser = £4.99. Label: 15. For large orhairy areasExcipients include propylene glycolECONAZOLE NITRATECautions see notes abovePregnancy minimal absorption from skin; not knownto be harmfulSide-effects see notes aboveLicensed use Pevaryl c , no age range specified bymanufacturerIndication and doseFungal skin infectionsApply twice dailyFungal nail infectionsApply once daily under occlusive dressingVaginal candidiasis section 7.2.2Pevaryl c (Janssen)Cream, econazole nitrate 1%, net price 30 g = £2.65Excipients include butylated hydroxyanisole, fragranceKETOCONAZOLECautions see notes above; do not use within 2 weeksof a potent topical corticosteroid for seborrhoeicdermatitis—risk of skin sensitisationSide-effects see notes aboveIndication and doseTinea pedisApply twice dailyOther fungal infectionsApply 1–2 times dailySystemic or resistant fungal infections section5.2.2Vulval candidiasis section 7.2.2Nizoral c (Janssen) A1Cream, ketoconazole 2%, net price 30 g = £3.40Excipients include cetyl alcohol, polysorbates, propylene glycol, stearylalcoholNote A 15-g tube is available for sale to the public for thetreatment of tinea pedis, tinea cruris, and candidal intertrigoShampoo—section 13.91. D except for seborrhoeic dermatitis and pityriasisversicolor and endorsed ‘SLS’MICONAZOLE NITRATECautions see notes aboveSide-effects see notes aboveLicensed use Licensed for use in children (age rangenot specified by manufacturer)Indication and doseFungal skin infectionsNeonate apply twice daily continuing for 10 daysafter lesions have healedChild 1 month–18 years apply twice daily continuingfor 10 days after lesions have healedFungal nail infectionsApply 1–2 times daily13 Skin