BNF for Children 2011-2012

BNFC 2011–2012 11.4.2 Other anti-inflammatory preparations 523Optilast c (Meda) AEye drops, azelastine hydrochloride 0.05%. Net price8 mL = £6.40Excipients include benzalkonium chloride, disodium edetateEMEDASTINESide-effects transient burning or stinging; blurredvision, local oedema, keratitis, irritation, dry eye,lacrimation, corneal infiltrates (discontinue) andstaining; photophobia; headache, and rhinitis occasionallyreportedIndication and doseSeasonal allergic conjunctivitisChild 3–18 years apply twice dailyEmadine c (Alcon) AEye drops, emedastine 0.05% (as difumarate), netprice 5 mL = £7.31Excipients include benzalkonium chlorideAlomide c (Alcon) AOphthalmic solution (= eye drops), lodoxamide 0.1%(as trometamol). Net price 10 mL = £5.21Excipients include benzalkonium chloride, disodium edetateNote Lodoxamide 0.1% eye drops can be sold to the publicfor treatment of allergic conjunctivitis in children over 4yearsNEDOCROMIL SODIUMSide-effects transient burning and stinging; distinctivetaste reportedIndication and doseSeasonal and perennial allergic conjunctivitisChild 6–18 years apply twice daily increased ifnecessary to 4 times daily; max. 12 weeks treatmentfor seasonal allergic conjunctivitisVernal keratoconjunctivitisChild 6–18 years apply 4 times dailyEPINASTINE HYDROCHLORIDESide-effects burning; less commonly dry mouth, tastedisturbance; nasal irritation, rhinitis; headache, blepharoptosis,conjunctival oedema and hyperaemia,dry eye, local irritation, photophobia, visual disturbance;pruritusIndication and doseSeasonal allergic conjunctivitisChild 12–18 years apply twice daily; max. durationof treatment 8 weeksRelestat c (Allergan) AEye drops, epinastine hydrochloride 500 micrograms/mL,net price 5 mL = £9.90Excipients include benzalkonium chloride, disodium edetateKETOTIFENSide-effects transient burning or stinging, punctatecorneal epithelial erosion; less commonly dry eye,subconjunctival haemmorhage, photophobia; headache,drowsiness, skin reactions, and dry mouth alsoreportedIndication and doseSeasonal allergic conjunctivitisChild 3–18 years apply twice dailyZaditen c (Novartis) AEye drops, ketotifen (as fumarate) 250 micrograms/mL, net price 5 mL = £7.80Excipients include benzalkonium chlorideLODOXAMIDESide-effects burning, stinging, itching, blurred vision,tear production disturbance, and ocular discomfort;less commonly, flushing, nasal dryness, dizziness,drowsiness, headache, blepharitis, and keratitisIndication and doseAllergic conjunctivitisChild 4–18 years apply 4 times dailyNote Improvement of symptoms may sometimes requiretreatment for up to 4 weeksRapitil c (Sanofi-Aventis) AEye drops, nedocromil sodium 2%. Net price 5 mL =£4.92Excipients include benzalkonium chloride, disodium edetateOLOPATADINESide-effects local irritation; less commonly keratitis,dry eye, local oedema, photophobia; headache, asthenia,dizziness; dry nose also reportedIndication and doseSeasonal allergic conjunctivitisChild 3–18 years apply twice daily; max. durationof treatment 4 monthsOpatanol c (Alcon) AEye drops, olopatadine (as hydrochloride) 1 mg/mL,net price 5 mL = £3.91Excipients include benzalkonium chlorideSODIUM CROMOGLICATE(Sodium cromoglycate)Side-effects transient burning and stingingIndication and doseAllergic conjunctivitis, vernal keratoconjunctivitisApply eye drops 4 times dailySodium Cromoglicate (Non-proprietary) AEye drops, sodium cromoglicate 2%. Net price13.5 mL = £1.79Brands include Hay-Crom c Aqueous, Opticrom c Aqueous,Vividrin cNote Sodium cromoglicate 2% eye drops can be sold to thepublic (in max. pack size of 10 mL) for treatment of acuteseasonal and perennial allergic conjunctivitisSingle useCatacrom c (Moorfields)Eye drops, sodium cromoglicate 2%, net price 30 x0.3 mL = £8.9911 Eye