BNF for Children 2011-2012

BNFC 2011–2012 9.6.7 Multivitamin preparations 487Neokay c (Neoceuticals) ACapsules, brown, phytomenadione 1 mg in an oilybasis, net price 12-cap pack = £3.95; 100-cap pack =£34.00Note The contents of one capsule should be administered bycutting the narrow tubular tip off and squeezing the liquidcontents into the mouth; if the baby spits out the dose or issick within three hours of administration a replacement doseshould be givenDoseNeonatal prophylaxis of vitamin-K deficiency bleedingsee notes aboveColloidal formulationKonakion c MM (Roche) AInjection, phytomenadione 10 mg/mL in a mixedmicelles vehicle. Net price 1-mL amp = 38pExcipients include glycocholic acid 54.6 mg/amp, lecithinCautions reduce dose in liver impairment (glycocholic acid maydisplace bilirubin); reports of anaphylactoid reactionsAdministration Konakion c MM may be administered by slowintravenous injection or by intravenous infusion in glucose 5%;not for intramuscular injectionKonakion c MM Paediatric (Roche) TAInjection, phytomenadione 10 mg/mL in a mixedmicelles vehicle, net price 0.2-mL amp = 95pExcipients include glycocholic acid 10.9 mg/amp, lecithinCautions parenteral administration in premature infants bodyweightless than 2.5 kg (increased risk of kernicterus)Administration Konakion c MM Paediatric may be administeredby mouth or by intramuscular injection or by intravenousinjection. For intravenous injection, may be diluted with Glucose5% if necessary9.6.7 MultivitaminpreparationsMultivitamin supplements are used in children withvitamin deficiencies and also in malabsorption conditionssuch as cystic fibrosis or liver disease. To avoidpotential toxicity, the content of all vitamin preparations,particularly vitamin A, should be considered whenused together with other supplements. Supplementationis not required if nutrient enriched feeds are used;consult a dietician for further advice.MULTIVITAMIN PREPARATIONSCautions see individual vitamins; vitamin A concentrationof preparations variesContra-indications see individual vitaminsSide-effects see individual vitaminsLicensed use Dalivit c not licensed for use inchildren under 6 weeksIndication and doseSee under preparations belowVitaminsCapsules, ascorbic acid 15 mg, nicotinamide 7.5 mg,riboflavin 500 micrograms, thiamine hydrochloride1 mg, vitamin A 2500 units, vitamin D 300 units, netprice 28-cap pack = £1.50DosePrevention of deficiency. By mouthChild 1–12 years 1 capsule dailyChild 12–18 years 2 capsules dailyCystic fibrosis: prevention of deficiency. By mouthChild 1–18 years 2–3 capsules dailyAbidec c (Chefaro UK)Drops, vitamins A, B group, C, and D. Net price 25 mL(with dropper) = £2.20Note Contains 1333 units of vitamin A (as palmitate) per 0.6 mLdoseExcipients include arachis (peanut) oil and sucroseDosePrevention of deficiency. By mouthPreterm neonate 0.6 mL dailyNeonate 0.3 mL dailyChild 1 month–1 year 0.3 mL dailyChild 1–18 years 0.6 mL dailyCystic fibrosis: prevention of deficiency. By mouthChild 1 month–1 year 0.6 mL dailyChild 1–18 years 1.2 mL dailyDalivit c (LPC)Oral drops, vitamins A, B group, C, and D, net price25 mL = £2.98, 50 mL = £4.85Note Contains 5000 units of vitamin A (as palmitate) per 0.6 mLdoseExcipients include sucroseDosePrevention of deficiency. By mouthNeonate (including preterm) 0.3 mL dailyChild 1 month–1 year 0.3 mL dailyChild 1–18 years 0.6 mL dailyCystic fibrosis: prevention of deficiency. By mouthChild 1 month–1 year 0.6 mL dailyChild 1–18 years 1 mL dailyVitamin and mineral supplements andadjuncts to synthetic dietsForceval c (Alliance)Capsules, brown/red, vitamins (ascorbic acid 60 mg,biotin 100 micrograms, cyanocobalamin 3 micrograms,folic acid 400 micrograms, nicotinamide18 mg, pantothenic acid 4 mg, pyridoxine 2 mg, riboflavin1.6 mg, thiamine 1.2 mg, vitamin A 2500 units,vitamin D 2400 units, vitamin E 10 mg, minerals andtrace elements (calcium 100 mg, chromium200 micrograms, copper 2 mg, iodine 140 micrograms,iron 12 mg, magnesium 30 mg, manganese3 mg, molybdenum 250 micrograms, phosphorus77 mg, potassium 4 mg, selenium 50 micrograms, zinc15 mg), net price 15-cap pack = £2.83, 30-cap pack =£5.19, 90-cap pack = £12.53. Label: 25DoseVitamin and mineral deficiency and as adjunct insynthetic dietsChild 12–18 years 1 capsule daily one hour after a mealJunior capsules, brown, vitamins (ascorbic acid25 mg, biotin 50 micrograms, cyanocobalamin9 Nutrition and blood