BNF for Children 2011-2012

72 1.9.4 Pancreatin BNFC 2011–20121 Gastro-intestinal systemChild 1–18 years 2–6 capsules with meals, swallowedwhole or sprinkled on foodCapsules ‘125’, pancreatin (pork), providing minimumof: protease 160 units, lipase 2950 units, amylase3300 units, net price 300-cap pack = £9.72. Counselling,see doseDose. By mouthNeonate contents of 1–2 capsules in each feed (or mixwith feed and give by spoon)Tablets, e/c, pancreatin (pork), providing minimumof: protease 110 units, lipase 1900 units, amylase1700 units, net price 300-tab pack = £4.51. Label: 5,25, counselling, see doseDose. By mouthChild 2–18 years 5–15 tablets before mealsTablets forte, e/c, pancreatin (pork), providing minimumof: protease 330 units, lipase 5600 units, amylase5000 units, net price 300-tab pack = £13.74. Label: 5,25, counselling, see doseDose. By mouthChild 2–18 years 6–10 tablets before mealsPowder, pancreatin (pork), providing minimum of:protease 1400 units, lipase 25 000 units, amylase30 000 units/g, net price 300 g = £24.28. Counselling,see doseDose. By mouthNeonate 250–500 mg with each feedChild 1 month–18 years 0.5–2 g with meals, washeddown or mixed with milk or waterNutrizym 22 c (Merck Serono) ACapsules, red/yellow, enclosing e/c minitablets ofpancreatin (pork), providing minimum of: protease1100 units, lipase 22 000 units, amylase 19 800 units,net price 100-cap pack = £33.33. Counselling, seeabove and under doseDose. By mouthChild 15–18 years 1–2 capsules with meals and 1capsule with snacks, swallowed whole or contents takenwith water or mixed with soft food (then swallowedimmediately without chewing), see notes abovePancrease HL c (Janssen) ACapsules, enclosing light brown e/c minitablets ofpancreatin (pork), providing minimum of: protease1250 units, lipase 25 000 units, amylase 22 500 units.Net price 100 = £31.70. Counselling, see above andunder doseDose. By mouthChild 15–18 years 1–2 capsules during each meal and 1capsule with snacks swallowed whole or contents mixedwith slightly acidic liquid or soft food (then swallowedimmediately without chewing), see notes aboveHigher-strength preparationsSee warning aboveCounselling It is important to ensure adequate hydration at alltimes in children receiving higher-strength pancreatin preparations.Creon c 25 000 (Abbott Healthcare) ACapsules, orange/clear, enclosing brown-colourede/c pellets of pancreatin (pork), providing: protease(total) 1000 units, lipase 25 000 units, amylase18 000 units, net price 100-cap pack = £28.25. Counselling,see above and under doseDose. By mouthChild 2–18 years initially 1 capsule with meals eithertaken whole or contents mixed with fluid or soft food(then swallowed immediately without chewing), seenotes aboveCreon c 40 000 (Abbott Healthcare) ACapsules, brown/clear, enclosing brown-colourede/c granules of pancreatin (pork), providing: protease(total) 1600 units, lipase 40 000 units, amylase25 000 units, net price 100-cap pack = £60.00. Counselling,see above and under doseDose. By mouthChild 2–18 years initially 1–2 capsules with meals eithertaken whole or contents mixed with fluid or soft food(then swallowed immediately without chewing), seenotes above