BNF for Children 2011-2012

58 1.6.1 Bulk-forming laxatives BNFC 2011–20121 Gastro-intestinal systemIndication and doseSee under preparationsCounselling Preparations that swell in contact with liquidshould always be carefully swallowed with water and shouldnot be taken immediately before going to bedFibrelief c (Manx)Granules, sugar- and gluten-free, ispaghula husk3.5 g/sachet (natural or orange flavour), net price 10sachets = £1.23, 30 sachets = £2.07. Label: 13, counselling,see aboveExcipients include aspartame (section 9.4.1)DoseConstipation. By mouthChild 12–18 years 1–6 sachets daily in water in 1–3divided doses, preferably after mealsFybogel c (Reckitt Benckiser)Granules, buff, effervescent, sugar- and gluten-free,ispaghula husk 3.5 g/sachet (low Na + ), net price 30sachets (plain, lemon, or orange flavour) = £1.84.Label: 13, counselling, see aboveExcipients include aspartame 16 mg/sachet (see section 9.4.1)DoseConstipation. By mouthChild 6–12 years ½–1 level 5-mL spoonful in watertwice daily, preferably after mealsChild 12–18 years 1 sachet (or 2 level 5-mL spoonfuls)in water twice daily, preferably after mealsIsogel c (Potters)Granules, brown, sugar- and gluten-free, ispaghulahusk 90%. Net price 200 g = £2.67. Label: 13, counselling,see aboveDoseConstipation. By mouthChild 6–12 years 1 level 5-mL spoonful in water once ortwice daily, preferably at mealtimesChild 12–18 years 2 level 5-mL spoonfuls in water onceor twice daily, preferably at mealtimesNote May be difficult to obtainIspagel Orange c (LPC)Granules, beige, effervescent, sugar- and gluten-free,ispaghula husk 3.5 g/sachet, net price 30 sachets =£2.10. Label: 13, counselling, see aboveExcipients include aspartame (section 9.4.1)DoseConstipation. By mouthChild 6–12 years ½–1 level 5-mL spoonful in watertwice daily, preferably after mealsChild 12–18 years 1 sachet (or 2 level 5-mL spoonfuls)in water 1–3 times daily, preferably after mealsRegulan c (Procter & Gamble)Powder, beige, sugar- and gluten-free, ispaghula husk3.4 g/5.85-g sachet (orange or lemon/lime flavour).Net price 30 sachets = £2.44. Label: 13, counselling,see aboveExcipients include aspartame (section 9.4.1)DoseConstipation. By mouthChild 6–12 years ½–1 level 5-mL spoonful in water 1–3times daily, preferably after mealsChild 12–18 years 1 sachet in 150 mL water 1–3 timesdaily, preferably after mealsMETHYLCELLULOSECautions see under Ispaghula HuskContra-indications see under Ispaghula Husk; alsoinfective bowel diseaseSide-effects see under Ispaghula HuskLicensed use no age limit specified by manufacturerIndication and doseSee under preparation belowCounselling Preparations that swell in contact with liquidshould always be carefully swallowed with water and shouldnot be taken immediately before going to bedCelevac c (Amdipharm)Tablets, pink, scored, methylcellulose ‘450’ 500 mg,net price 112-tab pack = £3.22. Counselling, see aboveand doseDoseConstipation, diarrhoea (see notes above). By mouthChild 7–12 years 2 tablets twice dailyChild 12–18 years 3–6 tablets twice dailyAdministration In constipation the dose should be takenwith at least 300 mL liquid. In diarrhoea, ileostomy, andcolostomy control, avoid liquid intake for 30 minutes beforeand after doseExtemporaneous formulations available seeExtemporaneous Preparations, p. 6STERCULIACautions see under Ispaghula HuskContra-indications see under Ispaghula HuskSide-effects see under Ispaghula HuskIndication and doseConstipation for dose see under preparationCounselling Preparations that swell in contact with liquidshould always be carefully swallowed with water and shouldnot be taken immediately before going to bedNormacol c (Norgine)Granules, coated, gluten-free, sterculia 62%. Netprice 500 g = £5.94; 60 7-g sachets = £4.99.Label: 25, 27, counselling, see aboveDose. By mouthChild 6–12 years ½–1 heaped 5-mL spoonful or thecontents of ½–1 sachet, washed down without chewingwith plenty of liquid once or twice daily after mealsChild 12–18 years 1–2 heaped 5-mL spoonfuls or thecontents of 1–2 sachets, washed down without chewingwith plenty of liquid once or twice daily after mealsAdministration May be mixed with soft food (e.g. yoghurt)before swallowing, followed by plenty of liquid.Normacol Plus c (Norgine)Granules, brown, coated, gluten-free, sterculia 62%,frangula (standardised) 8%. Net price 500 g = £6.34;60 7 g sachets = £5.34. Label: 25, 27, Counselling,see aboveDose. By mouthChild 6–12 years ½-1 heaped 5-mL spoonful or thecontents of ½-1 sachet, washed down without chewingwith plenty of liquid, once or twice daily after mealsChild 12–18 years 1–2 heaped 5-mL spoonfuls or thecontents of 1–2 sachets, washed down without chewingwith plenty of liquid, once or twice daily after meals