BNF for Children 2011-2012

522 11.4.2 Other anti-inflammatory preparations BNFC 2011–201211 EyeSingle useMinims c Dexamethasone (Bausch & Lomb) AEye drops, dexamethasone sodium phosphate 0.1%.Net price 20 0.5 mL = £9.38Excipients include disodium edetateWith antibacterialsMaxitrol c (Alcon) AUEye drops, dexamethasone 0.1%, hypromellose 0.5%,neomycin 0.35% (as sulphate), polymyxin B sulphate6000 units/mL. Net price 5 mL = £1.68Excipients include benzalkonium chloride, polysorbate 20Eye ointment, dexamethasone 0.1%, neomycin0.35% (as sulphate), polymyxin B sulphate6000 units/g. Net price 3.5 g = £1.44Excipients include hydroxybenzoates (parabens), wool fatSofradex c (Sanofi-Aventis) AUDrops (for ear or eye), see section 12.1.1FLUOROMETHOLONECautions see notes aboveSide-effects see notes aboveLicensed use not licensed for use in children under 2yearsIndication and doseLocal treatment of inflammation (short-term)Apply 2–4 times daily (initially every hour for 24–48 hours then reduce frequency)FML c (Allergan) AOphthalmic suspension (= eye drops), fluorometholone0.1%, polyvinyl alcohol (Liquifilm c ) 1.4%.Net price 5 mL = £1.71; 10 mL = £2.95Excipients include benzalkonium chloride, disodium edetate, polysorbate80HYDROCORTISONE ACETATECautions see notes aboveSide-effects see notes aboveIndication and doseLocal treatment of inflammation (short-term)Apply eye drops 4 times daily; apply eye ointmenttwice daily or at nightHydrocortisone (Non-proprietary) AEye drops, hydrocortisone acetate 1%. Net price10 mL = £3.21Eye ointment, hydrocortisone acetate 0.5%, net price3 g = £2.88; 1%, 3 g = £6.71PREDNISOLONECautions see notes aboveSide-effects see notes aboveIndication and doseLocal treatment of inflammation (short-term)Apply every 1–2 hours until controlled then reducefrequencyPred Forte c (Allergan) AEye drops, prednisolone acetate 1%. Net price 5 mL =£1.52; 10 mL = £3.05Excipients include benzalkonium chloride, disodium edetate, polysorbate80Predsol c (UCB Pharma) ADrops (for ear or eye), prednisolone sodium phosphate0.5%. Net price 10 mL = £1.92Excipients include benzalkonium chloride, disodium edetateSingle useMinims c Prednisolone Sodium Phosphate (Bausch& Lomb) AEye drops, prednisolone sodium phosphate 0.5%. Netprice 20 0.5 mL = £10.08Excipients include disodium edetateWith neomycinPredsol-N c (UCB Pharma) AUDrops (for ear or eye), see section 12.1.111.4.2 Other anti-inflammatorypreparationsEye drops containing antihistamines, such as antazoline(with xylometazoline as Otrivine-Antistin c ),azelastine, epinastine, ketotifen, and olopatadine,can be used for allergic conjunctivitis.Sodium cromoglicate and nedocromil sodium eyedrops may be useful for vernal keratoconjunctivitisand other allergic forms of conjunctivitis.Lodoxamide eye drops are used for allergic conjunctivalconditions including seasonal allergic conjunctivitis.Emedastine eye drops are licensed for seasonal allergicconjunctivitis.ANTAZOLINE SULPHATEIndication and doseAllergic conjunctivitisSee preparation belowOtrivine-Antistin c (Novartis Consumer Health)Eye drops, antazoline sulphate 0.5%, xylometazolinehydrochloride 0.05%. Net price 10 mL = £2.35Excipients include benzalkonium chloride, disodium edetateDoseChild 12–18 years apply 2–3 times daily (max. duration7 days)Note Xylometazoline is a sympathomimetic; it should beused with caution in patients susceptible to angle-closureglaucoma; absorption of antazoline and xylometazoline mayresult in systemic side-effects and the possibility of interactionwith other drugs, see Appendix 1 (antihistamines andsympathomimetics)AZELASTINE HYDROCHLORIDESide-effects mild transient irritation; bitter tastereportedIndication and doseAllergic conjunctivitis, seasonal allergic conjunctivitisChild 4–18 years apply twice daily, increased ifnecessary to 4 times dailyPerennial conjunctivitisChild 12–18 years apply twice daily, increased ifnecessary to 4 times daily; max. duration oftreatment 6 weeks