Guidelines for ATC classification and DDD assignment - WHOCC

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particularly methicillin susceptible S. aureus, might occur.
J01DE Fourth-generation cephalosporins
The fourth generation cephalosporins have activity against grampositive
cocci and a broad array of gram-negative bacteria, including P.
aeruginosa and many of the Enterobacteriaceae with inducible
chromosomal �-lactamases.
J01DF Monobactams
Arginin and lysine salts of aztreonam are classified in J01DF01; thus
aztreonam for inhalation is classified together with systemic
formulations.
J01DH Carbapenems
Combinations with enzyme inhibitors are classified at separate
5th levels, using the 50-series.
J01DI Other cephalosporins
J01E SULFONAMIDES AND TRIMETHOPRIM
This group comprises systemic sulfonamide and trimethoprim
preparations. Combinations of sulfonamide and trimethoprim are
classified in J01EE. Preparations containing two or more sulfonamides
are classified within the different 4th levels, using the 5th level code 20.
In such combinations, the half-life of the most long-acting sulfonamide
determines the classification. Sulfonamides in combinations with other
antibacterials (excl. trimethoprim) are classified in J01R. Dapsone is
classified in J04 - Antimycobacterials. See also A07A - Intestinal
antiinfectives.
Preparations, which in addition contain a urine acidifier, such as vitamin
C, calcium- or ammonium chloride, are classified at the plain 5th levels.
The DDDs for the sulfonamides are related to the duration of effect,
i.e. usually the long-acting sulfonamides will have lower DDDs
than the short-acting.