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Guidelines for ATC classification and DDD assignment - WHOCC

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The <strong>DDD</strong>s are mainly based on prophylaxis of allograft transplant<br />

rejection.<br />

The <strong>DDD</strong> <strong>for</strong> muromonab-CD3 is based on combination therapy in<br />

acute allograft rejection.<br />

The <strong>DDD</strong> <strong>for</strong> efalizumab is based on the treatment of plaque psoriasis.<br />

The <strong>DDD</strong>s <strong>for</strong> etanercept, infliximab, leflunomide, anakinra <strong>and</strong><br />

adalimumab are based on the treatment of rheumatoid arthritis.<br />

The <strong>DDD</strong> <strong>for</strong> certolizumab pegol is based on the treatment of Crohn’s<br />

Disease.<br />

The <strong>DDD</strong> <strong>for</strong> thalidomide is based on the treatment of erythema<br />

nodosum leprosum.<br />

The <strong>DDD</strong> <strong>for</strong> lenalidomide is based on the treatment of<br />

myelodysplastic syndromes.<br />

L04AA Selective immunosuppressants<br />

Antilymphocyte immunoglobulin from horse serum is classified in<br />

L04AA03.<br />

Antithymocyte immunoglobulin from rabbit serum is classified in<br />

L04AA04.<br />

L04AB Tumor necrosis factor alpha (TNF-�) inhibitors<br />

L04AC Interleukin inhibitors<br />

L04AD Calcineurin inhibitors<br />

L04AX Other immunosuppressants<br />

Methotrexate in oral <strong>for</strong>mulations is classified here, other routes of<br />

administration, see L01BA.<br />

191

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