PCT/2001/12 : PCT Gazette, Weekly Issue No. 12, 2001 - WIPO

12/2001
22 Mar/mar 2001 PCT Gazette - Section I - Gazette du PCT 4757
COMPOSES D’ETHER 3-PYRROLIDI-
NYLOXY-3’-PYRIDYLE UTILISES
COMME REGULATEURS DE LA
TRANSMISSION SYNAPTIQUE CHI-
MIQUE
(71) ABBOTT LABORATORIES [US/US];
Dept. 377/AP6D-2, 100 Abbott Park Road,
Abbott Park, IL 60064-6050 (US).
(72) LIN, Nan-Horng; 432 West Sycamore
Street, Vernon Hills, IL 60061 (US). LI,
Yihong; 14066 Honeytree Drive, Camel, IN
46032 (US). DRIZIN, Irene; 16764 West
Cherrywood Lane, Wadsworth, IL 60083
(US). KINCAID, John, F.; 1710 West Hillcrest
Drive, Newbury Park, CA 91320 (US).
BASHA, Anwer; 41 Heron Road, Lake Forest,
IL 60045 (US). DONG, Liming; 11559
Westview Parkway, San Diego, CA 92126
(US). HAKEEM, Ahmed, A.; 7771 North
Nordica, Niles, IL 60714 (US).
(74) WARD, Michael, J. et al. / etc.; Dept.
377/AP6D-2, 100 Abbott Park Road, Abbott
Park, IL 60064-6050 (US).
(81) CA JP MX.
(84) EP (AT BE CH CY DE DK ES FI FR GB GR
IE IT LU MC NL PT SE).
(51) 7 C07D 405/14, 417/14, A61K 31/50, A61P
11/08
(11) WO 01/19818
(21) PCT/EP00/08900
(13) A1
(22) 12 Sep/sep 2000 (12.09.2000)
(25) en (26) en
(30) 99118235.3 14 Sep/sep 1999
(14.09.1999)
EP
(43) 22 Mar/mar 2001 (22.03.2001)
(54) PHTHALAZINONE DERIVATIVES AS
PD3/4 INHIBITORS
DERIVES DE PHTHALAZINONE UTI-
LISES COMME INHIBITEURS DE
PD3/4
(71) BYK GULDEN LOMBERG CHEMIS-
CHE FABRIK GMBH [DE/DE];
Patentabteilung, Byk-Gulden-Strasse 2,
78467 Konstanz (DE).
(for all designated States except / pour tous
les États désignés sauf US)
(72) ULRICH, Wolf-Rüdiger; Hebelstrasse 3,
78464 Konstanz (DE). THIBAUT, Ulrich;
Egger Wiese 14, 78464 Konstanz (DE).
HATZELMANN, Armin; Alter Wall 3,
78467 Konstanz (DE). BUNDSCHUH,
Daniela; Rheingutstrasse 17, 78462 Konstanz
(DE). BOSS, Hildegard; Flurweg 3a,
78464 Konstanz (DE). KLEY, Hans-Peter;
Im Weinberg 3b, 78476 Allensbach (DE).
(for all designated States except / pour tous
les États désignés sauf CA US)
(72, 75) STERK, Jan, Geert [NL/NL]; Stadhouderslaan
38, NL-3583 JJ Utrecht (NL).
(74) BYK GULDEN LOMBERG CHEMIS-
CHE FABRIK GMBH; Patentabteilung,
Byk-Gulden-Strasse 2, 78467 Konstanz
(DE).
(81) AE AL AU BA BG BR CA CN CZ EE GE
HR HU ID IL IN JP KR LT LV MK MX NO
NZ PL RO SG SI SK TR UA US VN YU ZA
ZW.
(84) EA (AM AZ BY KG KZ MD RU TJ TM); EP
(ATBECHCYDEDKESFIFRGBGRIE
IT LU MC NL PT SE).
(51) 7 C07D 409/04, A61K 31/44, A61P 19/00,
29/00
(11) WO 01/19819 (13) A2
(21) PCT/CA00/01058
(22) 13 Sep/sep 2000 (13.09.2000)
(25) en (26) en
(30) 60/153,903 14 Sep/sep 1999 US
(14.09.1999)
(43) 22 Mar/mar 2001 (22.03.2001)
(54) CARBOXYLIC ACIDS AND ACYL-
SULFONAMIDES, COMPOSITIONS
CONTAINING SUCH COMPOUNDS
AND METHODS OF TREATMENT
ACIDES CARBOXYLIQUES ET ACYL-
SULFONAMIDES, COMPOSITIONS
CONTENANT DE TELS COMPOSES
ET METHODES DE TRAITEMENT
(71) MERCK FROSST CANADA & CO.
[CA/CA]; 16711 Trans-Canada Highway,
Kirkland, Québec H9H 3L1 (CA).
(for all designated States except / pour tous
les États désignés sauf US)
(71, 72) LACOMBE, Patrick [CA/CA]; 16711
Trans-Canada Highway, Kirkland, Québec
H9H 3L1 (CA). LABELLE, Marc [CA/CA];
16711 Trans-Canada Highway, Kirkland,
Québec H9H 3L1 (CA). RUEL, Rejean
[CA/CA]; 16711 Trans-Canada Highway,
Kirkland, Québec H9H 3L1 (CA).
(74) MURPHY, Kevin, P. et al. / etc.; Swabey
Ogilvy Renault, Suite 1600, 1981 McGill
College Avenue, Montreal, Québec H3A 2Y3
(CA).
(81) AE AG AL AM AT AU AZ BA BB BG BR
BY BZ CA CH CN CR CU CZ DE DK DM
DZ EE ES FI GB GD GE GH GM HR HU ID
IL IN IS JP KE KG KR KZ LC LK LR LS LT
LU LV MA MD MG MK MN MW MX MZ
NO NZ PL PT RO RU SD SE SG SI SK SL
TJ TM TR TT TZ UA UG US UZ VN YU ZA
ZW.
(84) AP (GH GM KE LS MW MZ SD SL SZ TZ
UG ZW); EA (AM AZ BY KG KZ MD RU
TJ TM); EP (AT BE CH CY DE DK ES FI FR
GB GR IE IT LU MC NL PT SE); OA (BF BJ
CF CG CI CM GA GN GW ML MR NE SN
TD TG).
(51) 7 C07D 413/04, A01N 43/84 // (C07D
413/04, 265:00, 231:00)
(11) WO 01/19820
(21) PCT/EP00/08639
(13) A1
(22) 5 Sep/sep 2000 (05.09.2000)
(25) de (26) de
(30) 199 43 499.9 10 Sep/sep 1999
(10.09.1999)
DE
(43) 22 Mar/mar 2001 (22.03.2001)
(54) SUBSTITUTED
ZOXAZINONES
PYRAZOL-3-YLBEN-
PYRAZOL-3-YLBENZOXAZINONES
SUBSTITUEES
(71) BASF AKTIENGESELLSCHAFT
[DE/DE]; 67056 Ludwigshafen (DE).
(for all designated States except / pour tous
les États désignés sauf US)
(72, 75) ZAGAR, Cyrill [DE/DE]; Georg-Herwegh-Str.
31, 67061 Ludwigshafen (DE).
MENKE, Olaf [DE/DE]; Lerchenweg 3,
67317 Altleiningen (DE). HAMPRECHT,
Gerhard [DE/DE]; Rote-Turm-Str. 28,
69469 Weinheim (DE). PUHL, Michael
[DE/DE]; Bürstädter Str. 95, 68623 Lampertheim
(DE). REINHARD, Robert
[DE/DE]; Pranckhstrasse 41, 67061 Ludwigshafen
(DE). SAGASSER, Ingo
[DE/DE]; Schlesienstr. 13, 67125
Dannstadt-Schauernheim (DE). WEST-
PHALEN, Karl-Otto [DE/DE]; Zum
Pfauenturm 17, 67346 Speyer (DE). OT-
TEN, Martina [DE/DE]; Gunterstr. 28,
67069 Ludwigshafen (DE). WALTER, Helmut
[DE/DE]; Grünstadter Str. 82, 67283
Obrigheim (DE).
(74) BASF AKTIENGESELLSCHAFT; 67056
Ludwigshafen (DE).
(81) AE AG AL AM AT AU AZ BA BB BG BR
BY BZ CA CH CN CR CU CZ DE DK DM
DZ EE ES FI GB GD GE GH GM HR HU
ID IL IN IS JP KE KG KP KR KZ LC LK
LR LS LT LU LV MA MD MG MK MN MW
MX MZ NO NZ PL PT RO RU SD SE SG SI
SK SL TJ TM TR TT TZ UA UG US UZ VN
YU ZA ZW.
(84) AP (GH GM KE LS MW MZ SD SL SZ TZ
UG ZW); EA (AM AZ BY KG KZ MD RU
TJ TM); EP (AT BE CH CY DE DK ES FI FR
GB GR IE IT LU MC NL PT SE); OA (BF BJ
CF CG CI CM GA GN GW ML MR NE SN
TD TG).
Published / Publiée :(c)
(51) 7 C07D 413/12, 261/20, 413/14, 471/04,
409/14, 333/56, 409/12, 498/04, A61K
31/42, 31/38, 31/47, 31/44, C07D 213/61,
C07C 251/48 // (C07D 413/12, 261:00,
211:00) (C07D 413/12, 333:00, 261:00)
(11) WO 01/19821 (13) A1
(21) PCT/US00/24961
(22) 13 Sep/sep 2000 (13.09.2000)
(25) en (26) en
(30) 09/395,937 14 Sep/sep 1999 US
(14.09.1999)
(43) 22 Mar/mar 2001 (22.03.2001)
(54) BENZISOXAZOLYL-, PYRIDOISOX-
AZOLYL- AND BENZTHIENYL-PHE-
NOXY DERIVATIVES USEFUL AS D4
ANTAGONISTS
DERIVES BENZISOXAZOLYLE, PY-
RIDOISOXAZOLYLE- ET BENZTHIE-
NYLE DU PROPYLE A SUBSTITU-
TION PHENOXY, ANTAGONISTES DU
D4
(63) US 09/395,937 (CON)
14 Sep/sep 1999 (14.09.1999)
(71) AVENTIS PHARMACEUTICALS INC.
[US/US]; Route 202-206, P.O. Box 6800,
Bridgewater, NJ 08876-0800 (US).
(for all designated States except / pour tous
les États désignés sauf US)
(72, 75) SHUTSKE, Gregory, M. [US/US]; 3
Dark Hollow Road, Pittstown, NJ 08867
(US). HENDRIX, James, A. [US/US]; 4 Aspen
Drive, Hillsborough, NJ 08876 (US). JU-
RCAK, John, G. [US/US]; 2431 13th Street,
Bethlehem, PA 18017 (US). FREED, Brian,
S. [US/US]; 47 Puddingstone Way, Phillipsburg,
NJ 08865 (US). HRIB, Nicholas,
J. [US/US]; 2402 Jamestown Common,