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Program - Brookhaven National Laboratory

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are currently used in some hadrontherapy facilities around the world. However, as carbon nuclei penetrate<br />

the human tissues, they may undergo inelastic nuclear reactions leading to the production of secondary<br />

fragments. Such fragments generate a spatial dose distribution, inside and outside the tumor region,<br />

different from that of the primary beam and their different linear energy transfer results in a different<br />

biological effectiveness for the same delivered dose. All these effects arising from the carbon fragmentation<br />

have to be correctly evaluated when planning a tumor treatment. In treatment planning systems the<br />

only way to overcome the shortcomings of analytical calculations is the use of reliable Monte Carlo codes.<br />

However, the physical models used in the Monte Carlo codes need to be tuned and validated by experimental<br />

fragmentation data. Since a limited set of experimental fragmentation cross sections is available and in<br />

particular, to our knowledge, no double differential fragmentation cross sections at intermediate energies<br />

are present in literature, a systematic of high quality double differential cross section measurements is<br />

mandatory. In order to provide an extensive set of fragmentation data to benchmark the Monte Carlo<br />

codes for their use in hadrontherapy, we have studied the fragmentation of a 12 C beam at 62 AMeV<br />

on a thin Carbon target at the INFN - Laboratori Nazionali del Sud (LNS) in Catania. The double<br />

differential cross sections and the angular distributions of the secondary fragments have been measured<br />

over a wide angular range at intermediate energy. The availability of double differential fragmentation<br />

cross sections at intermediate energy is of particular interest in order to accurately predict the fluences<br />

of the secondary fragments and their angular distributions within the human tissues. Indeed, although<br />

therapeutic carbon beams have energies of the order of hundreds MeV/u, the carbon ions lose their energy<br />

passing through the patient’s body so that the inelastic nuclear reactions may occur at energies much lower<br />

than the incident ones. Our measurements offer, therefore, a unique opportunity to test the performances<br />

of the nuclear reaction models implemented in the Monte Carlo codes for their use in hadrontherapy. In<br />

this contribution, together with the experimental results, we will also discuss the comparison between the<br />

measured fragmentation cross sections and the Geant4 [2] Monte Carlo predictions. In particular, two<br />

Geant4 nuclear reaction models, the Binary Light Ions Cascade and the Quantum Molecular Dynamic,<br />

have been compared and validated. Our results represent the first comparison of the Geant4 nuclear<br />

reaction models performed so far by using experimental data obtained with a thin target at intermediate<br />

energies. This work was supported by the Ion Beam Applications (IBA) company and by the European<br />

Space Agency (ESA) - tender AO6041.<br />

[1] U. Amaldi and G. Kraft, Rep. Prog. Phys. 68 (2005), 18611882. [2] Geant4 Collaboration, S. Agostinelli<br />

et al., Nucl. Instr. Meth. 506 (2003) 250-303.<br />

PB 5 5:00 PM<br />

Measurement of Isomeric Yield Ratio for nat Sm(γ,xn) 143m,g Sm Reaction with<br />

Bremsstrahlung Energies<br />

Sung-Chul Yang<br />

Department of Physics, Kyungpook <strong>National</strong> University, Daegu 702-701, Republic of Korea & Nuclear<br />

Data Center, Korea Atomic Energy Research Institute, Daejeon 305-353, Republic of Korea<br />

Kwang Soo Kim, Kyung-Sook Kim, Manwoo Lee, Guinyun Kim<br />

Department of Physics, Kyungpook <strong>National</strong> University, Daegu 702-701, Republic of Korea<br />

Hyeong Il Kim, Young-Ouk Lee<br />

Nuclear Data Center, Korea Atomic Energy Research Institute, Daejeon 305-353, Republic of Korea<br />

Eunae Kim<br />

Division of Advanced Nuclear Engineering, Pohang University of Science and Technology, Pohang<br />

790-784, Republic of Korea<br />

225

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