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Everything Herbal - Main Page - PS-Survival.com

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Specific Vitamins, Herbs, Medications<br />

drugs used for Parkinson;s disease, due to the risk of increased problems with movement. The German Commission<br />

E monograph warns against the use of Kava during pregnancy and nursing. Safety in young children and those with<br />

severe liver or kidney disease has not been established.<br />

Transitioning from Medications<br />

If you're taking Xanax or other drugs in the benzodiazepine family, switching to Kava will be very difficult. You must<br />

seek a doctor's supervision, because withdrawal symptoms can be severe and even life-threatening. Additionally, if<br />

you are taking Xanax on an "as needed" basis to stop acute panic attacks, Kava cannot be expected to have the same<br />

rapidity of action. It is easier to make the switch from milder Antianxiety drugs, such as BuSpar, and antidepressants.<br />

Nonetheless, a doctor's supervision is still strongly advised.<br />

Interactions You Should Know About<br />

If you are taking Medications for insomnia or anxiety such as benzodiazepines; do not take Kava in addition to them.<br />

Antipsychotic drugs: Kava might increase the risk of a particular side effect consisting of sudden abnormal<br />

movements, called a dystonic reaction. Levodopa for Parkinson's disease: Kava might reduce its effectiveness.<br />

For the Benzodiazepine Family of Drugs the following Applies:<br />

·Kava - Possible Dangerous Interaction<br />

·Other Sedative Herbs - Possible Increased Action of Drug<br />

·Melatonin - May Be Helpful for Discontinuing Benzodiazepine Sleeping Pills<br />

This family of medications is used to treat anxiety and insomnia.<br />

Benzodiazepine drugs include<br />

alprazolam (Xanax)<br />

chlordiazepoxide hydrochloride (Libritabs, Librium, Lipoxide, Mitran, Reposans-10)<br />

clonazepam (Klonopin)<br />

clorazepate dipotassium (Gen-Xene, Tranxene-T, Tranxene-SD)<br />

diazepam (Diastat, Valium, Valrelease)<br />

estazolam (ProSom)<br />

flurazepam hydrochloride (Dalmane, Durapam)<br />

halazepam (Paxipam)<br />

lorazepam (Ativan)<br />

oxazepam (Serax)<br />

quazepam (Doral)<br />

temazepam (Restoril)<br />

triazolam (Halcion)<br />

and others<br />

Kava<br />

Possible Dangerous Interaction One report suggests that the <strong>com</strong>bination of kava and benzodiazepine drugs can lead<br />

to excessive sedation.1<br />

Other Sedative Herbs<br />

Possible Increased Action of Drug It may not be wise to <strong>com</strong>bine benzodiazepines with any herb that produces a<br />

sedative effect, such as ashwagandha, calendula, catnip, hops, lady's slipper, lemon balm, passionflower, sassafras,<br />

skullcap, valerian, or yerba mansa, due to the possibility that the sedative effects may be amplified.2–5<br />

Melatonin<br />

May Be Helpful for Discontinuing Benzodiazepine Sleeping Pills Many people who take conventional sleeping pills<br />

(most of which are in the benzodiazepine family) find it difficult to quit. If you try to stop taking your medication, you<br />

may experience severe insomnia or interrupted sleep. A double-blind placebo-controlled study of 34 individuals who<br />

regularly used such medications found that melatonin at a dose of 2 mg nightly (controlled-release formulation) could<br />

help them discontinue the use of the drugs.6<br />

Warning: It can be dangerous to stop using benzodiazepines if you have taken them for a while. Consult your<br />

physician before trying melatonin to help you stop taking them.<br />

-----------------------------------------------------<br />

References<br />

1. Almeida JC and Grimsley EW. Coma from the health food stores: Interaction between kava and alprazolam. Ann<br />

Intern Med 125(11): 940–941, 1996.<br />

2. Brinker F. Herb contraindications and drug interactions, 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998: 32,<br />

33, 49, 84, 110, 134.<br />

3. Speroni E, et al. Sedative effects of crude extract of Passiflora incarnata after oral administration. Phytother Res 10:<br />

S92–94, 1996.<br />

4. Speroni E, Minghetti A. Neuropharmacological activity of extracts from Passiflora incarnata. Planta Med 54:<br />

http://www.herbnet.<strong>com</strong>/ask%20the%20herbalist/asktheherbalist_questions%20on%20specifics.htm (13 of 46) [5/17/2004 9:08:17 AM]

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