My PhD dissertation - Institut Fresnel

3.3.6 Relevance of the Data Assessed and Influence of the Steric Strains on Alkane
V
Cleavage 36
4 A Novel Access to Atropisomeric Biphenylbisphosphines 39
4.1 Preparation of Enantiomerically Pure 6,6’-Dibromobiphenyl-2,2’-diol and Derivatives
Thereof 40
4.1.1 Racemic 6,6’-Dibromobiphenyl-2,2’-diol 41
4.1.2 Racemate Resolution of 6,6’-Dibromobiphenyl-2,2’-diol 42
4.1.3 Derivatization of 6,6’-Dibromobiphenyl-2,2’-diol 43
4.2 Preparation of Enantiomerically Pure 6,6’-Dibromobiphenyl-2,2’-dicarboxylic Acid and
Derivatives Thereof 45
4.2.1 Racemic 6,6’-Dibromobiphenyl-2,2’-dicarboxylic Acid 45
4.2.2 Racemate Resolution of 6,6’-Dibromobiphenyl-2,2’-dicarboxylic Acid 46
4.2.3 Derivatization of 6,6’-Dibromobiphenyl-2,2’-dicarboxylic Acid 47
4.3 Preparation of Biphenylbisphosphines 49
4.4 Dynamic 1 H-NMR Study of Some Biphenyl Substrates 53
4.4.1 The Use of Variable-Temperature NMR to Study Intramolecular Mobility 54
4.4.2 Coalescence Study of 2,2’-Dilithio-6,6’-bis(methoxymethoxy) biphenyl 57
4.4.3 Coalescence Study of 2,2’-Dilithio-6,6’-bis(methoxymethyl)biphenyl 60
5 Conclusions and Outlook 65