Using ChemFinder - CambridgeSoft

the hit portion of each molecule is highlighted in
red. If a search doesn’t find any hits, you are
returned to query mode.
Types of Structural Searches
There are five structural search types that can be
selected in the Preferences dialog box:
• Exact Substructure.
• Exact Full Structure.
• Identity.
• Similar Full Structure.
• Similar Substructure.
Substructure searches can be performed on single or
multiple fragments.
Substructure Searching
Substructure searching, the default searching type,
finds structures that contain the query and any
additional attachments at the open positions. Results
have the substructure highlighted in red. Using
ChemDraw Pro, you can attach different features,
such as atom lists and variable bond types, to a query
to perform a narrower or broader search.
For more information about what query features you
may use and how these features affect a search, see
“Appendix A: Structural Query Features” on page 1.
An example of substructure searching of
Cyclopentane:
This substructure query
NOTE: In searching substructures, ChemFinder
finds the substructure query regardless of its
orientation or drawing presentation in the targeted
molecules. Bonds shown in bold above are actually
highlighted in red in ChemFinder.
For more examples of substructure searching, see
“More Search Examples” on page 97.
Fragment Searching
You can draw more than one structure or structure
fragment in your substructure search query. You can
choose whether to permit fragments to overlap in the
target structure Search Preferences dialog box. For
more information, see “Chapter 8: Customizing
ChemFinder.”.
For example, if you perform the following
substructure query with “Query fragments can
overlap in target” selected:
ChemFinder 8 Chapter 5: Searching • 89
Structure Searching
HO
O
will hit
O
and other molecules
O