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Using ChemFinder - CambridgeSoft

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Administrator<br />

If you want to Then click<br />

Require that any<br />

reaction center present<br />

in the query overlap with<br />

reaction centers in the<br />

target. This preference<br />

applies only to reaction<br />

searching.<br />

Prohibit generic<br />

structures from hitting<br />

any other structures in a<br />

query.<br />

Require full-word text<br />

matching. If you do not<br />

check this box, the query<br />

will hit any matching<br />

text fragment.<br />

Require that the<br />

stereochemistry of the<br />

target structure match<br />

that of the query<br />

structure.<br />

Reaction query<br />

must hit reaction<br />

center.<br />

Generics hit only<br />

generics.<br />

Text: match full<br />

word only<br />

Match<br />

stereochemistry<br />

and click How to set<br />

how the<br />

stereochemistry is<br />

matched.<br />

The Stereochemical Search Preferences dialog<br />

box appears.<br />

4. Set the Tetrahedral stereo center hits:<br />

If you want a<br />

tetrahedral<br />

stereocenter in the<br />

query to<br />

Then<br />

match the target exactly. in Tetrahedral stereo<br />

center hits, click<br />

Same.<br />

match same or opposite<br />

configuration at the<br />

center of the target.<br />

in Tetrahedral stereo<br />

center hits, click<br />

Either.<br />

match any target. in Tetrahedral stereo<br />

center hits, click<br />

Any.<br />

match a relative<br />

relationship between<br />

centers<br />

click Thick bonds<br />

represent relative<br />

stereochemistry.<br />

When “Thick bonds represent relative<br />

stereochemistry” box is unchecked (default), thick<br />

bonds are interchangeable with hash/wedge bonds.<br />

When the box is checked, and “Tetrahedral stereo<br />

124•Chapter 8: Customizing <strong>ChemFinder</strong> <strong>CambridgeSoft</strong><br />

Setting Preferences

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