Eble JN, Sauter G., Epstein JI, Sesterhenn IA - iarc

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Dr Kyu Rae KIM Department of Pathology University of Ulsan College of Medicine Asan Medical Center 388-1 Pungnap-dong, Songpa-gu 138-736 Seoul KOREA Tel. +82 2 3010 4514 Fax. +82 2 472 7898 krkim@amc.seoul.kr Dr Howard S. LEVIN Department of Pathology Cleveland Clinic Foundation 9500 Euclid Avenue Cleveland, OH 44195-5038 USA Tel. +1 216 444 2843 Fax. +1 216 445 6967 levinh@ccf.org Dr L. Jeffrey MEDEIROS Division of Pathology & Laboratory Med. M.D. Anderson Cancer Center 1515, Holcombe Boulevard Box 0072 Houston, TX 77030 USA Tel. +1 713 794 5446 Fax. +1 713 745 0736 jmedeiro@mdanderson.org Dr Hartmut P.H. NEUMANN Dpt. of Nephrology and Hypertension Albert-Ludwigs-University Hugstetter Strasse 55 D-79106 Freiburg GERMANY Tel. +49 761 270 3578 / 3401 Fax. +49 761 270 3778 neumann@mm41.ukl.uni-freiburg.de Dr Maija KIURU Department of Medical Genetics Biomedicum Helsinki / University of Helsinki P.O. Box 63 (Haartmaninkatu 8) FIN-00014 Helsinki FINLAND Tel. +358-9-19125379 Fax. +358-9-19125105 E-mail maija.kiuru@helsinki.fi Dr W. Marston LINEHAN Urologic Oncology Branch NCI Center for Cancer Research National Institutes of Health Building 10, Room 2B47 Bethesda, MD 20892 USA Tel. +1 301 496 6353 Fax. +1 301 402 0922 Dr Maria J. MERINO Department of Surgical Pathology Building 10, Room 2N212 National Cancer Institute 9000, Rockville Pike Bethesda, MD 20892 USA Tel. +1 301 496 2441 Fax. +1 301 480 9488 mjmerino@mail.nih.gov Dr Manuel NISTAL Department of Morphology Universidad Autonoma de Madrid c/ Arzobispo Morcillo s/n 28029 Madrid SPAIN Tel. +34 91 727 7300 / 397 5323 Fax. +34 91 397 5353 Dr Paul KLEIHUES Department of Pathology University Hospital CH-8091 Zurich SWITZERLAND Tel. +41 1 255 3516 Fax. +41 1 255 4551 paul.kleihues@usz.ch Dr Leendert H.J. LOOIJENGA* Dept. of Pathology, Rm. Be 430b Erasmus University Med. Center Josephine Nefkens Inst. / Univ. Hosp. Rotterdam Laboratory for Experimental Patho-Oncology P.O. Box 2040 3000 CA Rotterdam THE NETHERLANDS Tel. +31 10 408 8329 / Fax. +31 10 408 8365 looijenga@leph.azr.nl Dr Helen MICHAEL Department of Pathology Indiana University School of Medicine Wishard Memorial Hospital 1001 West 10th Street Indianapolis, IN 46202 USA Tel. +1 317 630 7208 Fax. +1 317 630 7913 hmichael@iupui.edu Dr Lucien NOCHOMOVITZ Department of Pathology North Shore University Hospital 300 Community Drive Manhasset NY 11030 USA Tel. +1 516 562-3249 Fax. +1 516 562-4591 lnochomo@nshs.edu Dr Margaret A. KNOWLES Cancer Research UK Clinical Centre St James’ University Hospital Beckett Street Leeds, LS9 7TF UNITED KINGDOM Tel. +44 113 206 4913 Fax. +44 113 242 9886 margaret.knowles@cancer.org.uk Dr Antonio LOPEZ-BELTRAN* Unit of Anatomical Pathology Cordoba University Medical School Avenida Menendez Pidal s/n 14004 Cordoba SPAIN Tel. +34 957 218993 Fax. +34 957 218229 em1lobea@uco.es Dr Markku MIETTINEN Department of Soft Tissue Pathology Armed Forces Institute of Pathology 6825, 16th Street, N.W. Washington, DC 20306-6000 USA Tel. +1 202 782 2793 Fax. +1 202 782 9182 miettinen@afip.osd.mil Dr Esther OLIVA Pathology, Warren 2/Rm 251 A Massachusetts General Hospital 55 Fruit Street Boston, MA 02114 USA Tel. +1 617 724 8272 Fax. +1 617 726 7474 eoliva@partners.org Dr Gyula KOVACS* Laboratory of Molecular Oncology Department of Urology University of Heidelberg Im Neuenheimer feld 325 D 69120 Heidelberg GERMANY Tel. +49 6221 566519 Fax. +49 6221 564634 gyula.kovacs@urz.uni-heidelberg.de Dr J. Carlos MANIVEL Dept. of Laboratory Medicine & Pathology University of Minnesota, Medical School 420 Delaware St. S.E. MMC 76 Minneapolis, MN 55455 USA Tel. +1 612 273 5848 Fax. +1 612 273 1142 maniv001@umn.edu Dr Holger MOCH* Institute for Pathology University of Basel Schönbeinstrasse, 40 CH 4003 Basel SWITZERLAND Tel. +41 61 265 2890 Fax. +41 61 265 31 94 hmoch@uhbs.ch Dr Tim D. OLIVER Department of Medical Oncology Saint Bartholomew’s Hospital 1st Fl. KGV Building, West Smithfield London, EC1A 7BE UNITED KINGDOM Tel. +44 20 7601 8522 Fax. +44 20 7796 0432 c.l.crickmore@gmul.ac.uk Dr Marc LADANYI Department of Pathology Room S-801 Memorial Sloan-Kettering Cancer Center 1275, York Avenue New York, NY 10021 USA Tel. +1 212 639 6369 Fax. +1 212 717 3515 ladanyim@mskcc.org Dr Guido MARTIGNONI* Dipartimento di Patologia Sezione Anatomia Patologica Universita di Verona, Policlinico G.B. Rossi P.LE L.A. Scuro 10 37134 Verona ITALY Tel. +39 045 8074846 Fax. +39 045 8027136 guidomart@yahoo.com Dr Henrik MØLLER Thames’ Cancer Registry Guy’s, King’s, & St Thomas’ School of Med. King’s College London 1st Floor, Capital House 42 Weston Street London SE1 3QD UNITED KINGDOM Tel. +44 20 7378 7688 / Fax. +44 20 73789510 henrik.moller@kcl.ac.uk Dr J. Wolter OOSTERHUIS Department of Pathology, Room Be 200a Erasmus Medical Center Josephine Nefkens Institute PO Box 1738 3000 DR Rotterdam THE NETHERLANDS Tel. +31 10 40 88449 Fax. +31 10 40 88450 j.w.oosterhuis@erasmusmc.nl Dr Virpi LAUNONEN Department of Medical Genetics Biomedicum Helsinki / University of Helsinki P.O. Box 63 (Haartmaninkatu 8) FIN-00014 Helsinki FINLAND Tel. +358-9-1911 Fax. +358-9-19125105 virpi.launonen@helsinki.fi Dr Alexander MARX Department of Pathology University of Wuerzburg Josef-Schneider-Strasse 2 97080 Wuerzburg GERMANY Tel. +49 931 201 3776 Fax. +49 931 201 3440 / 3505 path062@mail.uni-wuerzburg.de Dr Rodolfo MONTIRONI* Institute of Pathological Anatomy & Histopathology University of Ancona School of Med. I-60020 Torrette, Ancona ITALY Tel. +39 071 5964830 Fax. +39 071 889985 r.montironi@popcsi.unian.it Dr Attilio ORAZI Department of Pathology Indiana University School of Medicine Riley Hospital, IU Medical Center 702 Barhhill Drive Room 0969 Indianapolis, IN 46202 USA Tel. +1 317 274 7250 Fax. +1 317 274 0149 aorazi@iupui.edu Dr Ivo LEUSCHNER Department of Pathology University of Kiel Michaelsstrasse 11 D-24105 Kiel GERMANY Tel. +49 431 597 3444 Fax. +49 431 597 3486 ileuschner@path.uni-kiel.de Dr David G. MCLEOD Urology Services, Ward 56 (CPDR) Walter Reed Army Medical Center 6900 Georgia Avenue, N.W. Washington, DC 20307-5001 USA Tel. +1 202 782 6408 Fax. +1 202 782 2310 david.mcleod@na.amedd.army.mil Dr F. Kash MOSTOFI Department of Genitourinary Pathology Armed Forces Institute of Pathology 14th and Alaska Avenue, NW Washington, DC 20306-6000 USA (deceased) Dr Chin-Chen PAN Department of Pathology Veterans General Hospital-Taipei No. 201, Sec. 2 Shih-Pai Road 11217 Taipei TAIWAN R.O.C. Tel. +886 2 28757449 ext. 213 Fax. +886 2 28757056 ccpan@vghtpe.gov.tw Contributors 301
Dr Ricardo PANIAGUA Department of Cell Biology and Genetics University of Alcala 28871 Alcala de Henares, Madrid SPAIN Tel. +34 1 885 47 51 Fax. + 34 91 885 47 99 ricardo.paniagua@uah.es dep402@uah.es Dr Victor E. REUTER Department of Pathology Memorial Sloan Kettering Cancer Center 1275, York Avenue New York, NY 10021 USA Tel. +1 212 639 8225 Fax. +1 212 717 3203 reuterv@mskcc.org Dr Bernd J. SCHMITZ-DRAGER Department of Urology Euromed-Clinic Europa-Allee 1 D-90763 Fürth GERMANY Tel. +49 911 971 4531 Fax. +49 911 971 4532 bsd@euromed.de Dr Stephan STÖRKEL Institute of Pathology University of Witten / Herdecke Helios-Klinikum Wuppertal Heusnerstrasse, 40 42283 Wuppertal GERMANY Tel. +49 202 896 2850 Fax. +49 202 896 2739 sstoerkel@wuppertal.helios-kliniken.de Dr David M. PARHAM Department of Pathology Arkansas Children’s Hospital 800, Marshall Street Little Rock, AR 72202-3591 USA Tel. +1 501 320 1307 Fax. +1 501 320 3912 parhamdavidm@uams.edu Dr Jae Y. RO Department of Pathology Asan Medical Center Ulsan University School of Medicine #3881 Pungnap-dong, Songpa-gu 138-736 Seoul KOREA Tel. +82 2 3010 4550 Fax. +82 2 472 7898 jaero@www.amc.seoul.kr Dr Mark Philip SCHOENBERG Brady Urological Institute Johns Hopkins Hospital 600 N Wolfe St. Marburg 150 Baltimore, MD 21287-2101 USA Tel. +1 410 955 1039 Fax. +1 410 955 0833 mschoenberg@jhmi.edu Dr Aleksander TALERMAN Department of Pathology Thomas Jefferson University Hospital Main Building 132 South 10th Street, Room 285Q Philadelphia, PA 19107-5244 USA Tel. +1 215 955 2433 Fax. +1 215 923 1969 Dr D. Max PARKIN Unit of Descriptive Epidemiology Intl. Agency for Research on Cancer (IARC) World Health Organization (WHO) 150, Cours Albert Thomas 69008 Lyon FRANCE Tel. +33 4 72 73 84 82 Fax. +33 4 72 73 86 50 parkin@iarc.fr Professor Mark A. RUBIN* Department of Urologic Pathology Brigham and Women’s Hospital Harvard Medical School 75 Francis Street Boston, MA 02115 USA Tel. +1 617 525 6747 Fax. +1 617 278 6950 marubin@partners.org Dr Isabell A. SESTERHENN* Department of Genitourinary Pathology Armed Forces Institute of Pathology 14th and Alaska Avenue, NW Rm. 2088 Washington, DC 20306-6000 USA Tel. +1 202 782 2756 Fax. +1 202 782 3056 Sesterhe@afip.osd.mil TYREE@afip.osd.mil Dr Pheroze TAMBOLI Department of Pathology M.D. Anderson Cancer Center 1515, Holcombe Boulevard Box 0085 Houston, TX 77030 USA Tel. +1 713 794 5445 Fax. +1 713 745 3740 ptamboli@mdanderson.org Dr M. Constance PARKINSON* UCL Hospitals Trust & Institute of Urology University College London Rockefeller Building University Street London, WC1E 6JJ UNITED KINGDOM Tel. +44 20 7679 6033 Fax. +44 20 7387 3674 rmkdhmp@ucl.ac.uk Dr H. Gil RUSHTON Department of Urology Children’s National Medical Center 111, Michigan Avenue N.W. Ste 500-3W Washington, DC 20010-2916 USA Tel. +1 202 884 5550 / 5042 Fax. +1 202 884 4739 hrushton@cnmc.org Dr David SIDRANSKY Dept. of Otolaryngology, Head & Neck Surgery, Oncology, Pathology, Urology & Cellular & Molecular Med. The Johns Hopkins University School of Medicine 818 Ross Research Bldg, 720 Rutland Avenue Baltimore, MD 21205-2196 USA Tel. +1 410 502 5153 / Fax. +1 410 614 1411 dsidrans@jhmi.edu Dr Puay H. TAN Department of Pathology Singapore General Hospital 1, Hospital Drive, Outram Road 169608 Singapore SINGAPORE Tel. +65 6321 4900 Fax. +65 6222 6826 gpttph@sgh.com.sg Dr Christian P. Pavlovich Assistant Professor of Urology Director, Urologic Oncology Johns Hopkins Bayview Medical Center Brady Urological Institute, A-345 4940 Eastern Avenue Baltimore, MD 21224 USA Tel. +1 410-550-3506 / Fax. +1 410-550-3341 cpavlov2@jhmi.edu Dr Wael A. SAKR* Department of Pathology Harper Hospital 3990, John R. Street Detroit, MI 48201 USA Tel. +1 313 745 2525 Fax. +1 313 745 9299 wsakr@dmc.org Dr Ronald SIMON Institut für Pathologie Universität Basel Schönbeinstrasse 40 4003 Basel SWITZERLAND Tel. +41 61 265 3152 Fax. +41 61 265 2966 ronald_simon_de@yahoo.de Dr Bernard TÊTU Service de Pathologie CHUQ, L’Hôtel-Dieu de Québec 11, Côte du Palais Québec, G1R 2J6 CANADA Tel. +1 418 691-5233 Fax. +1 418 691 5226 bernard.tetu@crhdq.ulaval.ca Dr Elizabeth J. PERLMAN Department of Pathology Children’s Memorial Hospital 2373 Lincoln N. A 203 Chicago, IL 60614 USA Tel. +1 773 880 4306 Fax. +1 773 880 3858 eperlman@childrensmemorial.org Dr Hemamali SAMARATUNGA Dept. of Pathology Sullivan Nicolaides Pathology 134, Whitmore Street Taringa, QLD 4068 AUSTRALIA Tel. +61 07 33778666 Fax. +61 07 33783089 / 33778724 hemamali@medihesa.com hema_samaratunga@snp.com.au Dr Leslie H. SOBIN Dept. of Hepatic & Gastrointestinal Pathology Armed Forces Institute of Pathology 14th Street and Alaska Avenue Washington, DC 20306 USA Tel. +1 202 782 2880 Fax. +1 202 782 9020 sobin@afip.osd.mil Dr Kaori TOGASHI Dept. of Nuclear Medicine & Diagnostic Imaging Graduate School of Medicine Kyoto University 54 Shogoin Kawahara-cho Kyoto 606-8507 JAPAN Tel. +81 75 751 3760 Fax. +81 75 771 9709 ktogashi@kuhp.kyoto-u.ac.jp Dr Paola PISANI Unit of Descriptive Epidemiology Office 519 Intl. Agency for Research on Cancer (IARC) World Health Organization (WHO) 150, Cours Albert Thomas 69008 Lyon FRANCE Tel. +33 4 72 73 85 22 Fax. +33 4 72 73 86 50 pisani@iarc.fr Dr Guido SAUTER* Institute for Pathology University of Basel Schönbeinstrasse 40 4003 Basel SWITZERLAND Tel. +41 61 265 2889 / 2525 Fax. +41 61 265 2966 Guido.Sauter@unibas.ch Dr Poul H. B. SORENSEN Depts. of Pathology and Pediatrics, BC Research Institute for Children's & Women's Health 950 West 28th Avenue, Room 3082 Vancouver (BC) V5Z 4H4 CANADA Tel. +1 604 875 2936 Fax. +1 604 875 3417 psor@interchange.ubc.ca Dr Lawrence TRUE Department of Pathology University of Washington Medical Center 1959, NE Pacific Street Seattle, WA 98195 USA Tel. +1 206 598 6400 / +1 206 548 4027 Fax. +1 206 598 4928 / 3803 ltrue@u.washington.edu Dr Andrew A. RENSHAW Baptist Hospital Department of Pathology 8900 N. Kendall Drive Miami, FL 33176 USA Tel. +1 305 5966525 Fax. +1 305 598 5986 AndrewR@bhssf.org Dr Paul F. SCHELLHAMMER Department of Urology Eastern Virginia Graduate School of Medicine 6333 Center Drive Elizabeth Building #1 Norfolk, VA 23502 USA Tel. +1 757 457 5175 / 5170 Fax. +1 757 627 3211 schellpf@evms.edu Dr John R. SRIGLEY* Laboratory Medicine The Credit Valley Hospital 2200, Eglinton Avenue, West Mississauga (Ontario) CANADA Tel. +1 905 813 2696 Fax. +1 905 813 4132 jsrigley@cvh.on.ca Dr Jerzy E. TYCZYNSKI Unit of Descriptive Epidemiology Office 518 Intl. Agency for Research on Cancer (IARC) World Health Organization (WHO) 150, Cours Albert Thomas 69008 Lyon FRANCE Tel. +33 4 72 73 84 97 Fax. +33 4 72 73 86 50 tyczynski@iarc.fr 302 Source of charts and photographs
Page 1 and 2:
World Health Organization Classific
Page 3 and 4:
This volume was produced in collabo
Page 5 and 6:
Contents 1 Tumours of the kidney 9
Page 7 and 8:
CHAPTER 1 Tumours of the Kidney Can
Page 9 and 10:
TNM classification of renal cell ca
Page 11 and 12:
one quarter of kidney cancers in bo
Page 13 and 14:
Familial renal cell carcinoma M.J.
Page 15 and 16:
Table 1.02 Genotype - phenotype cor
Page 17 and 18:
A B Fig. 1.11 A Multiple cutaneous
Page 19 and 20:
A B Fig. 1.14 Birt-Hogg-Dubé syndr
Page 21 and 22:
Clear cell renal cell carcinoma D.J
Page 23 and 24:
Fig. 1.20 Clear cell renal cell car
Page 25 and 26:
Papillary renal cell carcinoma B. D
Page 27 and 28:
A B Fig. 1.29 Papillary renal cell
Page 29 and 30:
Fig. 1.33 Chromophobe RCC with sarc
Page 31 and 32:
Carcinoma of the collecting ducts o
Page 33 and 34:
Renal medullary carcinoma C.J. Davi
Page 35 and 36:
Renal carcinomas associated with Xp
Page 37 and 38:
Renal cell carcinoma associated wit
Page 39 and 40:
Papillary adenoma of the kidney J.N
Page 41 and 42:
of this tumour. Microscopic extensi
Page 43 and 44:
A B Fig. 1.59 Metanephric adenoma.
Page 45 and 46:
esults in intratumoral aneurysms. O
Page 47 and 48:
peritumoural fibrous pseudocapsule.
Page 49 and 50:
increases in prevalence to approxim
Page 51 and 52:
Nephrogenic rests and nephroblastom
Page 53 and 54:
Cystic partially differentiated nep
Page 55 and 56:
A B Fig. 1.80 Clear cell sarcoma of
Page 57 and 58:
A B Fig. 1.85 Rhabdoid tumour of th
Page 59 and 60:
transcription factor is fused to th
Page 61 and 62:
Leiomyosarcoma S.M. Bonsib Definiti
Page 63 and 64:
Angiomyolipoma G. Martignoni M.B. A
Page 65 and 66:
melanocytic and smooth muscle marke
Page 67 and 68:
Multinucleated and enlarged ganglio
Page 69 and 70:
Haemangioma P. Tamboli Definition H
Page 71 and 72:
Fig. 1.107 Juxtaglomerular cell tum
Page 73 and 74:
Intrarenal schwannoma I. Alvarado-C
Page 75 and 76:
Mixed epithelial and stromal tumour
Page 77 and 78:
Synovial sarcoma of the kidney J.Y.
Page 79 and 80:
Renal carcinoid tumour L.R. Bégin
Page 81 and 82:
Primitive neuroectodermal tumour (E
Page 83 and 84:
Paraganglioma / Phaeochromocytoma P
Page 85 and 86:
Leukaemia A. Orazi Interstitial inf
Page 87 and 88:
WHO histological classification of
Page 89 and 90:
TNM classification of carcinomas of
Page 91 and 92:
The risk of bladder cancer goes dow
Page 93 and 94:
Tumour spread and staging Urinary b
Page 95 and 96:
feature in such patients undergoing
Page 97 and 98:
A Fig. 2.12 Infiltrative urothelial
Page 99 and 100:
A Fig. 2.15 A Infiltrating urotheli
Page 101 and 102:
A B Fig. 2.19 A Infiltrative urothe
Page 103 and 104:
Fig. 2.23 Infiltrative urothelial c
Page 105 and 106:
ing systems have been proposed on t
Page 107 and 108:
Non-invasive urothelial tumours G.
Page 109 and 110:
chronically inflamed urothelium and
Page 111 and 112:
Inverted papilloma G. Sauter Defini
Page 113 and 114:
muscle invasive disease, but there
Page 115 and 116:
Fig. 2.42 Non-invasive urothelial n
Page 117 and 118:
A Fig. 2.45 Non-invasive urothelial
Page 119 and 120:
for DBCCR1 silencing {984,2476}. Th
Page 121 and 122:
Squamous cell carcinoma D.J. Grigno
Page 123 and 124:
Fig. 2.51 Squamous cell carcinoma.
Page 125 and 126:
Adenocarcinoma A.G. Ayala P. Tambol
Page 127 and 128:
A B Fig. 2.61 A Adenocarcinoma in s
Page 129 and 130:
A B Fig. 2.65 Intramural urachal ca
Page 131 and 132:
Müllerian origin is postulated for
Page 133 and 134:
A Fig. 2.69 Small cell carcinoma. A
Page 135 and 136:
Carcinoid L. Cheng Definition Carci
Page 137 and 138:
Leiomyosarcoma J. Cheville Definiti
Page 139 and 140:
Osteosarcoma L. Guillou Definition
Page 141 and 142:
Leiomyoma J. Cheville Definition A
Page 143 and 144:
Haemangioma L. Cheng Definition Hae
Page 145 and 146:
Metastatic tumours and secondary ex
Page 147 and 148:
Tumours of the renal pelvis and ure
Page 149 and 150:
nodular, ulcerative or infiltrative
Page 151 and 152:
Tumours of the urethra F. Hofstädt
Page 153 and 154:
usually show enteric, colloid or si
Page 155 and 156:
CHAPTER 3X Tumours of of the the Pr
Page 157 and 158:
TNM classification of carcinomas of
Page 159 and 160:
contrast, mortality among migrants
Page 161 and 162:
Fig. 3.06 Transrectal ultrasound of
Page 163 and 164:
PSA-related diagnostic strategies.
Page 165 and 166:
A B C Fig. 3.10 A,B Section of pros
Page 167 and 168:
pale-clear, similar to benign gland
Page 169 and 170:
A B Fig. 3.20 A, B Adenocarcinoma w
Page 171 and 172:
prostate adenocarcinomas exhibit AR
Page 173 and 174:
A Fig. 3.27 A, B Foamy gland adenoc
Page 175 and 176:
A B Fig. 3.32 A Sarcomatoid carcino
Page 177 and 178:
A B Fig. 3.37 A Gleason score 1+1=2
Page 179 and 180:
A B Fig. 3.43 A Prostate cancer Gle
Page 181 and 182:
Fig. 3.48 Heat map-nature. From S.M
Page 183 and 184:
Fig. 3.51 Prostate cancer. Major su
Page 185 and 186:
many stage T1b cancers. Stage T2 Mo
Page 187 and 188:
Fig. 3.58 Patterns of seminal vesic
Page 189 and 190:
Prostatic intraepithelial neoplasia
Page 191 and 192:
A B Fig. 3.63 A Micropapillary high
Page 193 and 194:
A B Fig. 3.68 A Ductal carcinoma in
Page 195 and 196:
Ductal adenocarcinoma X.J. Yang L.
Page 197 and 198:
Papillary pattern can be seen in bo
Page 199 and 200:
A B Fig. 3.74 A Inflammation withou
Page 201 and 202:
Squamous neoplasms T.H. Van der Kwa
Page 203 and 204:
Neuroendocrine tumours P.A. di Sant
Page 205 and 206:
Mesenchymal tumours J. Cheville F.
Page 207 and 208:
Fig. 3.89 Sarcoma of the prostate.
Page 209 and 210:
Miscellaneous tumours P.H. Tan L. C
Page 211 and 212:
A Fig. 3.96 A Adenocarcinoma of the
Page 213 and 214:
WHO histological classification of
Page 215 and 216:
Introduction F.K. Mostofi I.A. Sest
Page 217 and 218:
wartime birth cohorts illustrate th
Page 219 and 220:
Similar tumours as those of group 1
Page 221 and 222:
crucial for the development of this
Page 223 and 224:
A B Fig. 4.09 Spermatocytic seminom
Page 225 and 226:
A B Fig. 4.14 Intratubular germ cel
Page 227 and 228:
A B Fig. 4.19 Seminoma. A Typical s
Page 229 and 230:
Fig. 4.24 Seminoma. Vascular invasi
Page 231 and 232:
Fig. 4.28 Spermatocytic seminoma wi
Page 233 and 234:
A B Fig. 4.33 Embryonal carcinoma.
Page 235 and 236:
A B Fig. 4.38 Yolk sac tumour. A En
Page 237 and 238:
have cytoplasmic lacunae that conta
Page 239 and 240:
A Fig. 4.46 Teratoma. A Longitudina
Page 241 and 242:
A B Fig. 4.51 A Cut surface of derm
Page 243 and 244:
Fig. 4.54 Mixed germ cell tumour. L
Page 245 and 246: Sex cord / gonadal stromal tumours
Page 247 and 248: A B C Fig. 4.67 Malignant Leydig ce
Page 249 and 250: A Fig. 4.73 A Sertoli cell tumour.
Page 251 and 252: ICD-O codes Granulosa cell tumour 8
Page 253 and 254: ICD-O code 8592/1 Clinical features
Page 255 and 256: A B Fig. 4.83 Germ cell-sex cord/go
Page 257 and 258: A Fig. 4.85 A, B Brenner tumour of
Page 259 and 260: typical grade III follicular morpho
Page 261 and 262: testicular parenchyma and tumour te
Page 263 and 264: A B the surgical scar and adjacent
Page 265 and 266: Immunoprofile Ordóñez and associa
Page 267 and 268: often have a grey-white cut surface
Page 269 and 270: Fig. 4.111 Angiomyofibroblastoma-li
Page 271 and 272: A B Fig. 4.119 Embryonal rhabdomyos
Page 273 and 274: Table 4.05 Secondary tumours of the
Page 275 and 276: WHO histological classification of
Page 277 and 278: A Fig. 5.04 A, B Squamous cell carc
Page 279 and 280: deformed by an exophytic mass. In s
Page 281 and 282: A B C Fig. 5.12 A Warty (condylomat
Page 283 and 284: A Fig. 5.20 Bowenoid papulosis. A,
Page 285 and 286: three had been circumcized by 9 yea
Page 287 and 288: Mesenchymal tumours J.F. Fetsch M.
Page 289 and 290: Fig. 5.31 Neurofibroma of the penis
Page 291 and 292: oectodermal tumour/Ewing sarcoma [p
Page 293 and 294: Secondary tumours of the penis C.J.
Page 295: Dr John N. EBLE* Dept. of Pathology
Page 299 and 300: Source of charts and photographs 1.
Page 301 and 302: References 1. Anon. (1955). Case re
Page 303 and 304: 115. Ariel I, Sughayer M, Fellig Y,
Page 305 and 306: 246. Birt AR, Hogg GR, Dube WJ (197
Page 307 and 308: 374. Cardone G, Malventi M, Roffi M
Page 309 and 310: 502. Corti B, Carella R, Gabusi E,
Page 311 and 312: 633. Donhuijsen K, Schmidt U, Richt
Page 313 and 314: 768. Fischer J, Palmedo G, von Knob
Page 315 and 316: 900. Goedert JJ, Cote TR, Virgo P,
Page 317 and 318: 1028. Hartmann A, Dietmaier W, Hofs
Page 319 and 320: 1162. Iezzoni JC, Fechner RE, Wong
Page 321 and 322: 1293. Keetch DW, Catalona WJ (1995)
Page 323 and 324: 1424. Ladanyi M, Lui MY, Antonescu
Page 325 and 326: 1548. Lopez-Beltran A, Croghan GA,
Page 327 and 328: 1681. McLaughlin JK, Silverman DT,
Page 329 and 330: 1816. Moudouni SM, En-Nia I, Rioux-
Page 331 and 332: 1945. Ohori M, Wheeler TM, Kattan M
Page 333 and 334: 2070. Phillips G, Kumari-Subaiya S,
Page 335 and 336: 2199. Riou G, Barrois M, Prost S, T
Page 337 and 338: 2327. Schmidt L, Junker K, Weirich
Page 339 and 340: 2450. Smith G, Elton RA, Beynon LL,
Page 341 and 342: 2572. Tamboli P, Mohsin SK, Hailema
Page 343 and 344: 2693. van Echten J, Timmer A, van d
Page 345 and 346: 2816. Wick MR, Berg LC, Hertz MI (1
Page 347 and 348:
2937. Zhuang Z, Park WS, Pack S, Sc
Page 349 and 350:
CCNB, 226 CCND1, 105, 108 CCND2, 22
Page 351 and 352:
J Juvenile type granulosa cell tumo
Page 353 and 354:
Promoter methylation, 21 Prostate s
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