Eble JN, Sauter G., Epstein JI, Sesterhenn IA - iarc

More documents

Recommendations

Info

Multiple leiomyomas of the skin, 18 Multiple renal tumours, 20 MYBL2, 108, 226 MYCL1, 226 MYCN, 226 Myf4, 277 MyoD1, 139, 276, 277 Myointimoma, 293-297 Myxofibrosarcoma, 293, 297 Myxoid chondrosarcoma, 37 Myxoma, 57 N N-acetyltransferase 2, 13 Nelson syndrome, 252 Neonatal jaundice, 223 Nephroblastic tumours, 10 Nephroblastoma, 12, 48-56, 87, 213, 218, 247, 263, 279 Nephroblastomatosis, 53, 54 Nephrogenic adenoma, 78, 99, 133, 156, 172 Nephrogenic metaplasia, 99 Nephrogenic rests, 10, 53 Nested variant of urothelial carcinoma, 99, 138 Neuroblastoma, 10, 39, 52, 84, 160, 213, 214, 247, 279 Neuroendocrine carcinoma, 10, 82, 135, 136, 248 Neuroendocrine tumours, 10, 16, 90, 153, 160, 172, 207 Neurofibroma, 145, 153, 258, 274, 293- 297 Neurofibromatosis, 51 Neurofibromatosis type 1, 145 Neuron specific enolase, 51, 66, 84, 138, 207, 273 NF2, 296 Nodular mesothelial hyperplasia, 270 Non-invasive papillary urothelial carcinoma, high grade, 90, 117 Non-invasive papillary urothelial carcinoma, low grade, 90, 104, 116 Non-invasive papillary urothelial neoplasm of low malignant potential, 90 Non-invasive urothelial neoplasia, 123 Non-invasive urothelial tumours, 110 Non-keratinizing squamous metaplasia, 114 NonO (p54NRB), 37 Normal urothelium, 112 Normocytic anaemia, 13 NRC-1, 25 NSE, 84, 274 NTRK3, 60 Nuclear grooves, 41, 258 O Obesity, 9, 13, 95, 164 Omphalocele, 52 Oncocyte, 42 Oncocytic tumour, 18, 21 Oncocytic variant, prostate carcinoma, 177 Oncocytoma, 10, 15, 39, 42, 43, 65, 66 Oncocytomatosis, 43 Oncocytosis, 43 Orchioblastoma, 238 ORTI, 62 Osseous metaplasia, 26, 44, 142 Ossifying renal tumour of infancy, 62 Ossifying renal tumour of infants, 10 Osteosarcoma, 63, 90, 102, 103, 142, 144, 153, 178, 209, 211, 247, 293, 297 Overweight, 12 P p14ARF, 121, 123 p15, 103, 107, 108, 121, 228 p16, 21, 107, 121, 130 p27, 17, 109, 122, 186, 187, 197 p63, 117, 118, 123, 174 Paget disease, 172, 281, 282, 285, 290, 291 PAP, See Prostatic acid phosphatase Papillary adenoma, 10, 41 Papillary carcinoma, 28, 281, 284, 287 Papillary necrosis, 151 Papillary renal adenomas, 41 Papillary renal cell carcinoma, 10, 15, 18, 27-29 Papillary serous carcinoma of the ovary, 100 Papillary urothelial neoplasm of low malignant potential, 104, 115, 116 Paraganglioma, 85, 90, 99, 136-138, 160, 213, 218, 263 Paraneoplastic endocrine syndromes, 13 Paratesticular liposarcoma, 275, 276 Paratesticular rhabdomyosarcoma, 275, 277 Parity, 13 Penile melanosis, 292 Perilobar nephrogenic rest, 53 Peripheral neuroectodermal tumour, 52 Peripheral neuroepithelioma, 247 Peritumoural fibrous pseudocapsule, 49, 53, 54 Perlman syndrome, 51 Pesticides, 12 Peutz-Jeghers syndrome, 253-255 Peyrone disease, 298 Phaeochromocytoma, 10, 15, 17, 85, 136, 153, 214 Phenacetin, 13, 94, 151 Phosphatidyl inositol-3-kinase (PI3K), 61 PI3/Akt, 186 PIN, See Prostatic intraepithelial neoplasia Placental alkaline phosphatase, 100, 229-238, 243, 245, 247, 249, 255, 256, 260, 261 Placental site trophoblastic tumour, 218, 243 PLAP, See Placental alkaline phosphatase Plasmacytoid carcinoma, 135 Plasmacytoid variant, urothelial carcinoma, 101 Plasmacytoma, 10, 86, 90, 101, 102, 147, 153, 157, 264, 265 Platelet-derived growth factor beta, 17 Pleuropulmonary blastoma, 76 PNET, 58, 59, 83, 84, 245-248, 279 Pneumothorax, 15, 20 Polycyclic aromatic hydrocarbons, 13 Polycythemia, 44, 48 Polyembryoma, 221, 247, 248, 250 Polyvesicular vitelline, 240, 242 Post-atrophic hyperplasia, prostate, 173, 175 Postoperative spindle cell nodule/tumour, 140, 145 Posttransplant lymphoproliferative disease, 147 PRCC, 15, 27, 28, 37 PRCC-TFE3 renal carcinomas, 37 Priapism, 298, 299 Primitive neuroectodermal tumour, 10, 83, 245, 246 Prolactin, 14 Promontory sign, 296 Subject index 357
Promoter methylation, 21 Prostate specific antigen, 154, 159, 161, 163-169, 172, 174, 177-179, 188- 190, 192, 194, 198, 199, 201-208, 212-214, 278 Prostate specific membrane antigen, 167, 172 Prostatic acid phosphatase, 81, 167, 172, 177, 178, 201, 204, 205, 208, 214 Prostatic intraepithelial neoplasia, 160, 174, 180, 186-188, 193-198 Protein degredation, 17 PSA, See Prostate specific antigen Psammoma bodies, 37, 41, 44, 45, 100, 252 Pseudoglandular spaces, 98 Pseudohermaphroditism, 51 Pseudohyperparathyroidism, 13 Pseudohyperplastic prostate cancer, 175 Pseudosarcomatous stromal reaction, 97 PTEN, 25, 32, 107, 185, 187 Pulmonary cysts, 20, 21 PUNLMP, 110, 113, 115-117, 122 Purkinje cells, 16 Pushing margin, 23 pVHL, 15, 16, 17 Pyogenic granuloma, 141 R Ras, 61, 122 RASSF1A, 25 RB1, 107 Rbx1, 17 RCC17, 37 Reactive atypia, 112 Reinke crystals, 251, 252 Renal adenomatosis, 41 Renal angiosarcoma, 64 Renal carcinoid tumour, 81 Renal carcinoma, 30, 52 Renal cell cancer, 12-31, 38, 39, 65, 299 Renal cell carcinoma, 14-34, 39, 41, 43, 65, 68, 75, 212, 279, 299 Renal Cell Carcinoma Marker antigen, 37 Renal cell carcinoma, unclassified, 10, 43 Renal failure, 67, 85, 147 Renal medullary carcinoma, 10, 35 Renal oncocytoma, 20, 42 Renal osteosarcoma, 63 Renin, 13, 48, 67, 72, 73 Renomedullary interstitial cell tumour, 10, 74 Retained placenta, 223 Rete adenomas, 256 Rete testis carcinoma, 266 Retina, 15, 16 Retinal anlage tumour, 272 Retinoblastoma, 107, 109, 122 Retrograde metastasis, 23 Rhabdoid cells, 79 Rhabdoid tumour, 10, 52, 58, 59, 160, 213 Rhabdoid tumour of the kidney (RTK), 58 Rhabdomyosarcoma, 102, 139, 145, 153, 160, 178, 209-211, 236, 248, 270, 274-277, 293, 296, 297 RNASEL, 184, 186 RTK, 58, 59 S S. haematobium, 124, 125, 130 S100 protein, 27, 47, 57, 66, 84, 137, 145, 146, 206, 247, 252, 254, 256- 259, 271, 273, 295 Sarcomatoid carcinoma, 64, 102, 108, 140, 142, 144, 153, 155, 157, 160, 178, 179, 236, 287, 288 Sarcomatoid change, 23, 43 Sarcomatoid variant, urothelial carcinoma, 102 Schiller-Duval bodies, 240 Schistosoma haematobium, 94, 124, 125, 130 Schistosoma japonicum, 124 Schistosoma mansoni, 124 Schistosomiasis, 124-127, 130, 142, 147, 205 Schwannoma, 56, 75, 153, 274, 293, 294, 295, 297 Sclerosing adenosis, 173 Sclerosing Sertoli cell tumour, 218, 253, 255 Sebaceous carcinoma, 281, 288 Seminoma, 160, 221-240, 244-249, 255, 256, 260 Seminoma with syncytiotrophoblastic cells, 218, 233 Serotonin, 138, 207 Serous carcinoma, 218 Serous tumour of borderline malignancy, 218 Sertoli cell tumour, 218, 232, 238, 253- 256, 258, 266 Sertoli cell tumour, lipid rich variant, 218 Serum alkaline phosphatase, 13 Sickle cell trait, 35 Signet-ring variant, 195 Simpson-Golabi-Behmel syndrome, 51 SIOP, 48, 49, 52 Skene glands, 90, 155 SMAD4, 225 Small cell carcinoma, 90, 135, 136, 153, 160, 207, 208, 281, 288 Small cell neuroendocrine carcinoma, 207 Small cell neuroendocrine variant, PIN, 196 Smooth muscle actin, 66, 69, 102, 144, 206, 257, 258, 259, 295, 296 Soft tissue alveolar soft part sarcoma, 37 Solitary fibrous tumour, 10, 75, 144, 160, 209, 211, 215, 258 Sotos syndrome, 51 Soya bean agglutinins, 40 Spermatocytic seminoma, 218, 221, 223-225, 229, 234-237 Spermatocytic seminoma with sarcoma, 218, 236, 237 Spermatogenesis, 230 Spermatogenic arrest, 231 Spermatogonia, 223, 230, 231 Spindle cell rhabdomyosarcoma, 275, 277 Squamous cell carcinoma, 90, 124-127, 153-156, 160, 205, 281-290 Squamous cell papilloma, 90, 127 SRD5A2, 164 SSX family gene, 80 Steroid 5-alpha reductase type II, 164 Stromal proliferations of uncertain malignant potential of the prostate, 209 Stromal sarcoma, 160, 209 Stromal tumour of uncertain malignant potential, 160, 209 STUMP, 209, 210 Sturge-Weber syndrome, 71, 146 Sustentacular cells, 85, 136, 137 Synaptophysin, 81, 82, 84, 85, 137, 138, 196, 207, 247, 273 Syncytiotrophoblastic cells, 103, 238, 243, 244, 249 358 Subject index
Page 1 and 2:
World Health Organization Classific
Page 3 and 4:
This volume was produced in collabo
Page 5 and 6:
Contents 1 Tumours of the kidney 9
Page 7 and 8:
CHAPTER 1 Tumours of the Kidney Can
Page 9 and 10:
TNM classification of renal cell ca
Page 11 and 12:
one quarter of kidney cancers in bo
Page 13 and 14:
Familial renal cell carcinoma M.J.
Page 15 and 16:
Table 1.02 Genotype - phenotype cor
Page 17 and 18:
A B Fig. 1.11 A Multiple cutaneous
Page 19 and 20:
A B Fig. 1.14 Birt-Hogg-Dubé syndr
Page 21 and 22:
Clear cell renal cell carcinoma D.J
Page 23 and 24:
Fig. 1.20 Clear cell renal cell car
Page 25 and 26:
Papillary renal cell carcinoma B. D
Page 27 and 28:
A B Fig. 1.29 Papillary renal cell
Page 29 and 30:
Fig. 1.33 Chromophobe RCC with sarc
Page 31 and 32:
Carcinoma of the collecting ducts o
Page 33 and 34:
Renal medullary carcinoma C.J. Davi
Page 35 and 36:
Renal carcinomas associated with Xp
Page 37 and 38:
Renal cell carcinoma associated wit
Page 39 and 40:
Papillary adenoma of the kidney J.N
Page 41 and 42:
of this tumour. Microscopic extensi
Page 43 and 44:
A B Fig. 1.59 Metanephric adenoma.
Page 45 and 46:
esults in intratumoral aneurysms. O
Page 47 and 48:
peritumoural fibrous pseudocapsule.
Page 49 and 50:
increases in prevalence to approxim
Page 51 and 52:
Nephrogenic rests and nephroblastom
Page 53 and 54:
Cystic partially differentiated nep
Page 55 and 56:
A B Fig. 1.80 Clear cell sarcoma of
Page 57 and 58:
A B Fig. 1.85 Rhabdoid tumour of th
Page 59 and 60:
transcription factor is fused to th
Page 61 and 62:
Leiomyosarcoma S.M. Bonsib Definiti
Page 63 and 64:
Angiomyolipoma G. Martignoni M.B. A
Page 65 and 66:
melanocytic and smooth muscle marke
Page 67 and 68:
Multinucleated and enlarged ganglio
Page 69 and 70:
Haemangioma P. Tamboli Definition H
Page 71 and 72:
Fig. 1.107 Juxtaglomerular cell tum
Page 73 and 74:
Intrarenal schwannoma I. Alvarado-C
Page 75 and 76:
Mixed epithelial and stromal tumour
Page 77 and 78:
Synovial sarcoma of the kidney J.Y.
Page 79 and 80:
Renal carcinoid tumour L.R. Bégin
Page 81 and 82:
Primitive neuroectodermal tumour (E
Page 83 and 84:
Paraganglioma / Phaeochromocytoma P
Page 85 and 86:
Leukaemia A. Orazi Interstitial inf
Page 87 and 88:
WHO histological classification of
Page 89 and 90:
TNM classification of carcinomas of
Page 91 and 92:
The risk of bladder cancer goes dow
Page 93 and 94:
Tumour spread and staging Urinary b
Page 95 and 96:
feature in such patients undergoing
Page 97 and 98:
A Fig. 2.12 Infiltrative urothelial
Page 99 and 100:
A Fig. 2.15 A Infiltrating urotheli
Page 101 and 102:
A B Fig. 2.19 A Infiltrative urothe
Page 103 and 104:
Fig. 2.23 Infiltrative urothelial c
Page 105 and 106:
ing systems have been proposed on t
Page 107 and 108:
Non-invasive urothelial tumours G.
Page 109 and 110:
chronically inflamed urothelium and
Page 111 and 112:
Inverted papilloma G. Sauter Defini
Page 113 and 114:
muscle invasive disease, but there
Page 115 and 116:
Fig. 2.42 Non-invasive urothelial n
Page 117 and 118:
A Fig. 2.45 Non-invasive urothelial
Page 119 and 120:
for DBCCR1 silencing {984,2476}. Th
Page 121 and 122:
Squamous cell carcinoma D.J. Grigno
Page 123 and 124:
Fig. 2.51 Squamous cell carcinoma.
Page 125 and 126:
Adenocarcinoma A.G. Ayala P. Tambol
Page 127 and 128:
A B Fig. 2.61 A Adenocarcinoma in s
Page 129 and 130:
A B Fig. 2.65 Intramural urachal ca
Page 131 and 132:
Müllerian origin is postulated for
Page 133 and 134:
A Fig. 2.69 Small cell carcinoma. A
Page 135 and 136:
Carcinoid L. Cheng Definition Carci
Page 137 and 138:
Leiomyosarcoma J. Cheville Definiti
Page 139 and 140:
Osteosarcoma L. Guillou Definition
Page 141 and 142:
Leiomyoma J. Cheville Definition A
Page 143 and 144:
Haemangioma L. Cheng Definition Hae
Page 145 and 146:
Metastatic tumours and secondary ex
Page 147 and 148:
Tumours of the renal pelvis and ure
Page 149 and 150:
nodular, ulcerative or infiltrative
Page 151 and 152:
Tumours of the urethra F. Hofstädt
Page 153 and 154:
usually show enteric, colloid or si
Page 155 and 156:
CHAPTER 3X Tumours of of the the Pr
Page 157 and 158:
TNM classification of carcinomas of
Page 159 and 160:
contrast, mortality among migrants
Page 161 and 162:
Fig. 3.06 Transrectal ultrasound of
Page 163 and 164:
PSA-related diagnostic strategies.
Page 165 and 166:
A B C Fig. 3.10 A,B Section of pros
Page 167 and 168:
pale-clear, similar to benign gland
Page 169 and 170:
A B Fig. 3.20 A, B Adenocarcinoma w
Page 171 and 172:
prostate adenocarcinomas exhibit AR
Page 173 and 174:
A Fig. 3.27 A, B Foamy gland adenoc
Page 175 and 176:
A B Fig. 3.32 A Sarcomatoid carcino
Page 177 and 178:
A B Fig. 3.37 A Gleason score 1+1=2
Page 179 and 180:
A B Fig. 3.43 A Prostate cancer Gle
Page 181 and 182:
Fig. 3.48 Heat map-nature. From S.M
Page 183 and 184:
Fig. 3.51 Prostate cancer. Major su
Page 185 and 186:
many stage T1b cancers. Stage T2 Mo
Page 187 and 188:
Fig. 3.58 Patterns of seminal vesic
Page 189 and 190:
Prostatic intraepithelial neoplasia
Page 191 and 192:
A B Fig. 3.63 A Micropapillary high
Page 193 and 194:
A B Fig. 3.68 A Ductal carcinoma in
Page 195 and 196:
Ductal adenocarcinoma X.J. Yang L.
Page 197 and 198:
Papillary pattern can be seen in bo
Page 199 and 200:
A B Fig. 3.74 A Inflammation withou
Page 201 and 202:
Squamous neoplasms T.H. Van der Kwa
Page 203 and 204:
Neuroendocrine tumours P.A. di Sant
Page 205 and 206:
Mesenchymal tumours J. Cheville F.
Page 207 and 208:
Fig. 3.89 Sarcoma of the prostate.
Page 209 and 210:
Miscellaneous tumours P.H. Tan L. C
Page 211 and 212:
A Fig. 3.96 A Adenocarcinoma of the
Page 213 and 214:
Page 215 and 216:
Introduction F.K. Mostofi I.A. Sest
Page 217 and 218:
wartime birth cohorts illustrate th
Page 219 and 220:
Similar tumours as those of group 1
Page 221 and 222:
crucial for the development of this
Page 223 and 224:
A B Fig. 4.09 Spermatocytic seminom
Page 225 and 226:
A B Fig. 4.14 Intratubular germ cel
Page 227 and 228:
A B Fig. 4.19 Seminoma. A Typical s
Page 229 and 230:
Fig. 4.24 Seminoma. Vascular invasi
Page 231 and 232:
Fig. 4.28 Spermatocytic seminoma wi
Page 233 and 234:
A B Fig. 4.33 Embryonal carcinoma.
Page 235 and 236:
A B Fig. 4.38 Yolk sac tumour. A En
Page 237 and 238:
have cytoplasmic lacunae that conta
Page 239 and 240:
A Fig. 4.46 Teratoma. A Longitudina
Page 241 and 242:
A B Fig. 4.51 A Cut surface of derm
Page 243 and 244:
Fig. 4.54 Mixed germ cell tumour. L
Page 245 and 246:
Sex cord / gonadal stromal tumours
Page 247 and 248:
A B C Fig. 4.67 Malignant Leydig ce
Page 249 and 250:
A Fig. 4.73 A Sertoli cell tumour.
Page 251 and 252:
ICD-O codes Granulosa cell tumour 8
Page 253 and 254:
ICD-O code 8592/1 Clinical features
Page 255 and 256:
A B Fig. 4.83 Germ cell-sex cord/go
Page 257 and 258:
A Fig. 4.85 A, B Brenner tumour of
Page 259 and 260:
typical grade III follicular morpho
Page 261 and 262:
testicular parenchyma and tumour te
Page 263 and 264:
A B the surgical scar and adjacent
Page 265 and 266:
Immunoprofile Ordóñez and associa
Page 267 and 268:
often have a grey-white cut surface
Page 269 and 270:
Fig. 4.111 Angiomyofibroblastoma-li
Page 271 and 272:
A B Fig. 4.119 Embryonal rhabdomyos
Page 273 and 274:
Table 4.05 Secondary tumours of the
Page 275 and 276:
Page 277 and 278:
A Fig. 5.04 A, B Squamous cell carc
Page 279 and 280:
deformed by an exophytic mass. In s
Page 281 and 282:
A B C Fig. 5.12 A Warty (condylomat
Page 283 and 284:
A Fig. 5.20 Bowenoid papulosis. A,
Page 285 and 286:
three had been circumcized by 9 yea
Page 287 and 288:
Mesenchymal tumours J.F. Fetsch M.
Page 289 and 290:
Fig. 5.31 Neurofibroma of the penis
Page 291 and 292:
oectodermal tumour/Ewing sarcoma [p
Page 293 and 294:
Secondary tumours of the penis C.J.
Page 295 and 296:
Dr John N. EBLE* Dept. of Pathology
Page 297 and 298:
Dr Ricardo PANIAGUA Department of C
Page 299 and 300:
Source of charts and photographs 1.
Page 301 and 302: References 1. Anon. (1955). Case re
Page 303 and 304: 115. Ariel I, Sughayer M, Fellig Y,
Page 305 and 306: 246. Birt AR, Hogg GR, Dube WJ (197
Page 307 and 308: 374. Cardone G, Malventi M, Roffi M
Page 309 and 310: 502. Corti B, Carella R, Gabusi E,
Page 311 and 312: 633. Donhuijsen K, Schmidt U, Richt
Page 313 and 314: 768. Fischer J, Palmedo G, von Knob
Page 315 and 316: 900. Goedert JJ, Cote TR, Virgo P,
Page 317 and 318: 1028. Hartmann A, Dietmaier W, Hofs
Page 319 and 320: 1162. Iezzoni JC, Fechner RE, Wong
Page 321 and 322: 1293. Keetch DW, Catalona WJ (1995)
Page 323 and 324: 1424. Ladanyi M, Lui MY, Antonescu
Page 325 and 326: 1548. Lopez-Beltran A, Croghan GA,
Page 327 and 328: 1681. McLaughlin JK, Silverman DT,
Page 329 and 330: 1816. Moudouni SM, En-Nia I, Rioux-
Page 331 and 332: 1945. Ohori M, Wheeler TM, Kattan M
Page 333 and 334: 2070. Phillips G, Kumari-Subaiya S,
Page 335 and 336: 2199. Riou G, Barrois M, Prost S, T
Page 337 and 338: 2327. Schmidt L, Junker K, Weirich
Page 339 and 340: 2450. Smith G, Elton RA, Beynon LL,
Page 341 and 342: 2572. Tamboli P, Mohsin SK, Hailema
Page 343 and 344: 2693. van Echten J, Timmer A, van d
Page 345 and 346: 2816. Wick MR, Berg LC, Hertz MI (1
Page 347 and 348: 2937. Zhuang Z, Park WS, Pack S, Sc
Page 349 and 350: CCNB, 226 CCND1, 105, 108 CCND2, 22
Page 351: J Juvenile type granulosa cell tumo
show all

Eble JN, Sauter G., Epstein JI, Sesterhenn IA - iarc

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?