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in vitro PHARMACOLOGY 2011 CATALOG - Cerep

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161<br />

HDACs ❚<br />

sirtu<strong>in</strong> 3<br />

Source<br />

Substrate<br />

Measured product<br />

Detection method<br />

human recomb<strong>in</strong>ant (E. coli)<br />

fluoro-lys<strong>in</strong>e sirtu<strong>in</strong> 2 deacetylase substrate<br />

(20 µM)<br />

fluoro-lys<strong>in</strong>e<br />

fluorimetry<br />

<br />

<br />

<br />

<br />

<br />

<br />

<br />

<strong>Cerep</strong><br />

services<br />

Ref. 2583<br />

Q 3 weeks<br />

Reference<br />

niac<strong>in</strong>amide (IC 50 : 31 µM)<br />

Michan, S. and S<strong>in</strong>clair, D. (2007) Biochem. J., 404: 1-13.<br />

<br />

<br />

Receptors<br />

<br />

<br />

<br />

<br />

<br />

Ion<br />

channels<br />

<br />

<br />

<br />

<br />

<br />

Transporters<br />

K<strong>in</strong>ases<br />

<br />

Epigenetic &<br />

DNA-related<br />

enzymes<br />

Other<br />

enzymes<br />

Specialized<br />

cellular<br />

assays<br />

Standard<br />

profiles<br />

Test<strong>in</strong>g<br />

conditions<br />

Order<strong>in</strong>g<br />

<strong>in</strong>formation<br />

For further details and updated <strong>in</strong>formation on assays:<br />

❚ Please go to www.cerep.com catalog onl<strong>in</strong>e or contact us at sales@cerep.com<br />

❚ Europe: +33 (0)5 49 89 30 00 – USA: +1 (425) 895 8666 – Japan: +81 (0)3 3354 4026 – Ch<strong>in</strong>a: +86 21 5132 0568<br />

Assay developed <strong>in</strong> 2010 New assay conditions Human Q Standard turnaround time<br />

Assay list<br />

& <strong>in</strong>dex

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