Research Profile - College of Medicine and Health Science - United ...

Department of Pathology
Research Profile
Associate Professor &
Acting Chair:
Dr A Castella
Professor:
Prof MM Agarwal
Associate Professor:
Dr Bassam Ali
Dr SM Chong
Assistant Professor:
Dr S Al Salam
Teaching Assistant:
Dr A Al Bawardi
Dr S Al Marzooqi
Medical Research
Specialist:
Ms A Mathew
Ms M Sudhadevi
Medical Secretary:
Ms K Al Ghanem
Research Assistant:
Ms N Akawi
Mr N Karavantevide
Pathology is a wide-ranging discipline of
laboratory medicine. It covers several research
fields, including histopathology, cytology,
laboratory hematology, clinical chemistry,
genetics and molecular biology.
Hematopathology: (Dr. Antonio Castella)
Lymphomas are malignant monoclonal disorders of the lymphatic
system, which show diverse clinical features, pathology and
outcome. The pathological classifications are controversial,
especially with regard to non-Hodgkin's lymphomas (NHL). In
recent years new classifications have been proposed which are
based on modern concepts of lymphocyte function. The latest
classifications of lymphomas (REALand WHO) are an attempt
to resolve the lack of uniformity in the reporting of malignant
lymphomas by defining the different types according to
morphology and immunology as well as cytogenetics.
Although lymphomas show a worldwide distribution, geographical
variations in their histopathologic pattern, especially NHL, are
well recognized. However, in the Middle East, and specifically in
the Gulf countries, there was a paucity of data concerning the
patterns of histopathologic subtypes of lymphomas.
The Pathology Department undertook a project, in collaboration
with Tawam and Al Ain Hospitals, to study the pattern of
lymphomas in the UAE.
The aim of this study was to analyze the distribution of the
various pathologic types of lymphoma in the native Arab
population of the UAE. More than 200 National patients with
lymphoma were studied. The cases were examined
morphologically and immunohistochemically with an extensive
panel of monoclonal antibodies, and are classified according to
the revised European-American classification of lymphoid
neoplasms (REAL). The results were compared with the
distribution of lymphomas in other Asian and Western countries.