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Research Profile - College of Medicine and Health Science - United ...

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Department<br />

<strong>of</strong> Physiology<br />

<strong>Research</strong> <strong>Pr<strong>of</strong>ile</strong><br />

Members <strong>of</strong> Staff <strong>of</strong> the Physiology Department<br />

have interests in neuroscience <strong>and</strong> muscle<br />

(including skeletal, cardiac <strong>and</strong> smooth muscle).<br />

The experimental work includes normal<br />

physiology as well as pathophysiology, particularly<br />

in relation to the peripheral nerves, autonomic<br />

nervous system, <strong>and</strong> heart in the diabetic state,<br />

which is a common disorder in the <strong>United</strong> Arab<br />

Emirates. The work requires complex<br />

electrophysiological <strong>and</strong> cellular methodologies,<br />

as well as electron microscopy, using in vitro <strong>and</strong><br />

in vivo techniques. Other departmental research<br />

interests include uterine smooth muscle<br />

physiology, cardiovascular <strong>and</strong> pulmonary effects<br />

<strong>of</strong> particulate air pollution <strong>and</strong> cancer biology.<br />

Aging <strong>and</strong> neurodegenerative disorders<br />

Studies on aging <strong>and</strong> neurodegenerative disorders have focused<br />

on synaptic plasticity <strong>and</strong> synaptic remodelling, particularly at<br />

the nerve-muscle junction in various peripheral neuropathies<br />

including those caused by diabetes, aging <strong>and</strong> heavy metal<br />

poisoning. Electrophysiological, laser confocal microscopy <strong>and</strong><br />

electronmicroscopy techniques are used in combination to<br />

focus on changes in muscular performance in these conditions.<br />

It is hypothesised that free radicals are involved in these nerve<br />

injuries <strong>and</strong> antioxidants like vitamin E & C may have a protective<br />

role. Studies on the cerebral microcirculation include changes<br />

in the susceptibilty to thrombus formation in the brain, <strong>and</strong> the<br />

effects <strong>of</strong> metals, aspirin <strong>and</strong> heat.<br />

Pr<strong>of</strong>essor & Chair:<br />

Pr<strong>of</strong> TE Adrian<br />

Pr<strong>of</strong>essor:<br />

Pr<strong>of</strong> M Fahim<br />

Pr<strong>of</strong> W Lammers<br />

Pr<strong>of</strong> M Ljubisavijevic<br />

Pr<strong>of</strong> FC Howarth<br />

Pr<strong>of</strong> J Morrison<br />

Associate Pr<strong>of</strong>essor:<br />

Dr A Nemmar<br />

Medical <strong>Research</strong><br />

Specialist:<br />

Mr S Dhanasekaran<br />

Ms K Parekh<br />

Mr MA Qureshi<br />

Ms B Stephen<br />

Ms Shaheen Zia<br />

<strong>Research</strong> Assistant:<br />

Ms Sneha Ann Thomas<br />

Secretary:<br />

Mr P Rajagopalan<br />

Office Assistant:<br />

Mr Saeed

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