(CAS) Bulletin - Tribunal Arbitral du Sport / TAS
(CAS) Bulletin - Tribunal Arbitral du Sport / TAS
(CAS) Bulletin - Tribunal Arbitral du Sport / TAS
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once would cause side effects to most people, but if<br />
the ingestion of 200 micrograms is part of a course of<br />
administration it would have no toxic effect.<br />
Furthermore, it was also clarifi ed and approved by<br />
all experts <strong>du</strong>ring the hearing that a person being<br />
subject to a clenbuterol administration course<br />
could reach a ‘steady-state’ within 5 days, i.e. a state<br />
where the level of clenbuterol in this person would<br />
remain stable even if clenbuterol is still ingested in<br />
the context of a clenbuterol administration doping<br />
regime. According to Dr Rabin, following multiple<br />
oral administrations (as per therapeutic regime), a<br />
steady-state concentration of clenbuterol in plasma<br />
is reached after ~4 days, with ~500-600 pg/mL in<br />
plasma corresponding to a 40 ug/12h administration<br />
regimen and 200-300 pg/mL to a 20 ug/12h dosing.<br />
According to Prof. Martín-Jiménez, the scenario of<br />
a 21-day course of clenbuterol administration of 200<br />
ug assumes that the donor was exceptionally reckless<br />
and underwent the treatment without any fear of<br />
detection as such levels of clenbuterol are detectable<br />
<strong>du</strong>ring a period of 31 to 36 days.<br />
This last argument was rebutted by WADA by<br />
stating that Mr Contador possibly transfused into his<br />
system the plasma of another person less likely to be<br />
submitted to a doping test.<br />
Based on the evidence of the experts’ opinions, the<br />
Panel notes that a single dose of 200 ug of clenbuterol<br />
is likely to cause toxic effects but that, through a<br />
planned clenbuterol regime a steady-state can be<br />
achieved, meaning that it is possible that a donor,<br />
used as an accomplice for the purpose of blood<br />
manipulations and not risking any doping tests, could<br />
be at the source of the plasma transfusion which the<br />
Appellants are alleging took place.<br />
However, the question arises what motive a person<br />
that is not likely to submit to doping controls might<br />
have to take large amounts of clenbuterol if such<br />
person only has the intention of donating plasma to<br />
an athlete involved in sports at the highest levels and<br />
has no personal ambition to perform in high-level<br />
competitive sports. Inversely, if the person did have<br />
personal ambitions of that type then why would he<br />
be a donor and why would Mr Contador choose this<br />
person to be his plasma donor?<br />
To sum up therefore on this point, the Panel fi nds that<br />
such a clenbuterol regime is theoretically possible,<br />
whether or not it were followed by the Athlete or<br />
by a third party functioning as donor, but that it is,<br />
however, rather unlikely that such a scenario actually<br />
happened.<br />
5.3.3.2 The donation shortly after the last<br />
administration<br />
Dr Martín-Jiménez is of the opinion that WADA’s<br />
blood transfusion scenario can only work if it is<br />
assumed that the donor withdrew his blood within<br />
24 hours after having taken the last in a series of<br />
21 doses of 200 ug of clenbuterol. According to Dr<br />
Martín-Jiménez such a scenario is not consistent. In<br />
essence, WADA is asking the Panel to accept that the<br />
donor is, on the one hand, assumed to be part of a<br />
sophisticated doping scheme yet, on the other, is so<br />
dim-witted that he donated blood just hours after<br />
having taken 200 ug of a drug that is known to have<br />
a notorious slow clearance time.<br />
The Panel fi nds that providing Dr. Martín-Jiménez’s<br />
foregoing opinion is correct it is indeed curious that<br />
Mr. Contador, who is a highly professional athlete,<br />
would, on the one hand, act in a sophisticated<br />
and planned manner (using blood transfusions in<br />
coordination with infusions of plasma and perhaps<br />
the services of a third person over a period of time<br />
as an accomplice for blood manipulations) and, on<br />
the other hand, act in such a negligent manner by<br />
receiving plasma from a donor having very recently<br />
fi nished a clenbuterol regime. Of course mistakes<br />
and miscalculations can occur; however the Panel<br />
fi nds that such a sequence of events is rather unlikely.<br />
5.3.3.3 The Athlete’s urine pro<strong>du</strong>ction<br />
The Athlete contends that WADA, by calculating<br />
his daily urine volume on the basis of the amount<br />
of urine reportedly provided by him <strong>du</strong>ring dopingcontrol<br />
tests, vastly underestimated both the daily<br />
urine volume pro<strong>du</strong>ced by an average male human<br />
and, more importantly, by himself.<br />
In Dr Rabin’s expert report attached to WADA’s<br />
supplementary brief, it is assumed “ that the First<br />
Respondent would have urinated once every three hours between<br />
the transfusion and the relevant test which is an extremely fair<br />
assumption in favour of the athlete”. WADA’s assumption<br />
is based on a mean volume per urination of 140 mL<br />
derived from “data about urine volume delivered by the<br />
athlete for several doping tests con<strong>du</strong>cted by the UCI”.<br />
Prof. Martín-Jiménez also assumed 8 urinations,<br />
i.e. one every 3 hours. However, WADA assumed a<br />
total daily urine volume of 1.12 L compared to Prof.<br />
Martín-Jiménez’s 1.5 L.<br />
The Boehringer Ingelheim study that delivered the<br />
Intravenous data relied upon by Dr Rabin was derived<br />
from six test subjects, one of whom was apparently<br />
of a similar weight to the Athlete. The conclusion of<br />
Jurisprudence majeure / Leading cases<br />
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