SUNDAY, APRIL 10 Across Societies – Experimental Biology

BIOCHEMISTRY561. CYTOKINE AND GROWTH FACTOR SIGNALINGPosterSUN. 7:30 AM—WASHINGTON CONVENTION CENTER, EXHIBITHALL ABCPresentation time: 1:05 PM-2:35 PMB314 561.1 Identifi cation of DNA topoisomerases inducedby interleukin-2 in HuT 78 cells. P.D. Foglesong, J. Ma, T.Jaiswal and T.A. Singh. Univ. of Incarnate Word, TX.B315 561.2 Interferon induced non-STAT dependentpathway and tumor suppression. P. Gade, U.B. Machani andD.V. Kalvakolanu. Univ. of Maryland Baltimore.B316 561.3 Structure-activity studies of competitive ligandbinding to neuropilin in angiogenesis. H-F. Guo, P. Xu, M.W.Parker and C.W. Vander Kooi. Univ. of Kentucky Col. of Med.B317 561.4 IL-1β induces FGF-2 production via PI 3-kinase/p38/NF-κB pathways in corneal endothelial cells. J.G. Lee andE.P. Kay. Doheny Eye Inst. and Keck Sch. of Med., Univ. ofSouthern California.B318 561.5 The potential of HGF and 2xInlB to activate theMet receptor and attenuate chondroitin sulfate proteoglycanexpression in astrocytes. T.T. Logan, P. Yu, H.M. Geller, O.Mungunsukh, R.M. Day and A.J. Symes. Uniformed Svcs.Univ. of Hlth. Sci., and NHLBI, NIH.B319 561.6 BDNF receptor TrkB modulates voltage-gatedK + (Kv) 1.5 channel protein expression. T.K. Makar, N.P.Nooli, V. Nimmagadda, G.K. Patibandla, R. Chakravarty,S.I. V. Judge, A. Maiti and C.T. Bever, Jr. Univ. of MarylandBaltimore.B320 561.7 Regulatory effect of CCL26 on cancer relatedgenes during infl ammation. R. Marijani, T. Mathews, H.McGann and B. Abonyo. Florida A&M Univ.B321 561.8 Organophosphates inhibit expression of growthfactors in neuroblastoma cells. T. Mathews, H. McGann, R.Marijani, N. Lamango and B. Abonyo. Florida A&M Univ.B322 561.9 Organophosphates induced A549 cell toxicityis accompanied by enhanced gene expression of infl ammatorycytokines. H. McGann, T. Mathews, R. Marijani, N. Lamangoand A. Barack. Florida A&M Univ.B323 561.10 Spontaneous autoactivation of the EGFreceptor induced by mutations in its C-terminal negativelycharged residues. H. Miyagi, A.S. Adenan, Z. Taoufiq and I.N.Maruyama. Okinawa Inst. of Sci. and Technol.B324 561.11 Exogenous and autocrine growth hormoneaffect LNCaP prostate cancer cell proliferation, survival andmotility A.O. Nakonechnaya, X. Chen, R.F. Overcash, H.S.Jefferson and B.M. Shewchuk. East Carolina Univ.B325 561.12 Transforming growth factor beta in inducedsputum and whole blood in cystic fi brosis. S. Schmitt-Grohé,L. van den Boom, D. Ngampolo, O. Eickmeier, R. Schubert,S. Zielen and M.J. Lentze. Univ. Hosp. Bonn and Univ. Hosp.Frankfurt.B326 561.13 Role of fi sh IFNγ-related gene in immunesystem. Y. Shibasaki, T. Yabu, T. Moritomo and T. Nakanishi.Nihon Univ. Col. of Bioresource Sci., Japan.B327 561.14 The functional association between fi lamin Band histone deacetylase 7 in endothelial cells. Y-T. Su, C. Gao,Y. Liu, P. Tempst, H. Erdjument-Bromage and H-Y. Kao. CaseWestern Reserve Univ. and Mem. Sloan-Kettering Cancer Ctr.B328 561.15 PAPP-A and IGFBP-4 in abmormal pregnancysera. O.A. Vanderpuye. Albany State Univ.B329 561.16 Interleukin-13 (IL-13)/IL-13 receptor α1signaling regulates intestinal epithelial cystic fi brosistransmembrane conductance regulator channel-dependent Cl -secretion. D.X. Y. Wu, R. Ahrens, H. Osterfeld, K. Groschwitz,P. Foster, M.E. Rothenberg, K.I. Matthaei, F.D. Finkelmanand S.P. Hogan. Cincinnati Children’s Hosp. Med. Ctr., Univ.of Newcastle, Australia and John Curtin Sch. of Med. Res.,Canberra.B330 561.17 Transforming growth factor β signaling inducescysteine-rich protein 2 expression in vascular smooth musclecells. S-F. Yet, M-L. Wu and Y-J. Jheng. Natl. Hlth. Res. Inst.,Zhuman, Taiwan.562. IMMUNE CELL SIGNALINGPosterSUN. 7:30 AM—WASHINGTON CONVENTION CENTER, EXHIBITHALL ABCPresentation time: 1:05 PM-2:35 PMSUNDAYB331 562.1 Enhanced T cell signaling in cells bearingLAT molecules resistant to ubiquitylation. L. Balagopalan, B.Ashwell, K. Bernot, I. Akpan, N. Quasba, V. Barr and L.E.Samelson. NCI, NIH.B332 562.2 Mitogen-activated protein kinase kinase kinase(MAP3K) and GTPase activity in human natural killer cellsexposed to dibutyltin. L. Celada and M.M. Whalen. TennesseeState Univ.B333 562.3 Expression of P2X7 receptor splice variants isdifferentially regulated in macrophages versus T lymphocytesand is modulated by infl ammatory cytokines. D.M. Chopyk, J.Robinson, K. Trueblood and G.R. Dubyak. Case WesternReserve Univ.B334 562.4 mAb BGD6, a mast cell lineage marker, bindsto a 110kDa protein unrelated to FcεRI E.Z. M. Da Silva, M.C.Jamur and C. Oliver. Fac. of Med. of Ribeirão Preto, Univ. ofSão Paulo.B335 562.5 Conditional deletion reveals a role for Sos1 inpre-TCR signaling and thymocyte development. R.L. Kortum,C.L. Sommers, C.P. Alexander, J.M. Pinski, N.N. Nath, A.Grinberg, P.E. Love and L.E. Samelson. NCI and NICHD,NIH.B336 562.6 TAK1 signaling is essential for macrophagesurvival. S.R. Mihaly and J. Ninomiya-Tsuji. North CarolinaState Univ.B337 562.7 A novel role for hydrogen sulfi de: enhancementof T-cell activation/proliferation and its regulation bythrombospondin-1/CD47. T.W. Miller, E.A. Wang, S. Gould,E.V. Stein and D.D. Roberts. NCI, NIH and George WashingtonUniv.B338 562.8 Activation of protein kinase D is part of the NKcell signaling pathway activated in the tumor-cell destroyingprocess. K. Rana and M.M. Whalen. Tennessee State Univ.B339 562.9 The brominated fl ame retardantshexabromcylododecane and tetrabromobisphenol a decreasesecretion of interferon gamma from human natural killer cells.J. Reid and M.M. Whalen. Tennessee State Univ.B340 562.10 Complex nano-scale organization and role ofLAT signaling complexes resolved at the single molecule level.E. Sherman, V. Barr, S. Manley, G. Patterson, L. Balagopalan,I. Akpan, C.K. Regan, J. Lippincott-Schwartz and L.E.Samelson. NCI and NICHD, NIH.154