SUNDAY, APRIL 10 Across Societies – Experimental Biology

SUNDAYD427 659.12 Cigarette smoke induces macrophageinhibitory cytokine 1 to dampen innate immunity in humanairway epithelial cells. Q. Wu, D. Jiang and H.W. Chu. Natl.Jewish Hlth.D428 659.13 Interaction between cigarette smoke andcyclic AMP signaling in human bronchial epithelial function.A. Oldenburger, W. Rijks, W. Poppinga, S.S. Roscioni, I.Heijink, H. Maarsingh and M. Schmidt. Univ. of Groningenand Univ. Med. Ctr. Groningen, Netherlands.D429 659.14 Thin layer mucus dynamics in ciliated cultures.P.R. Sears, C.W. Davis, M. Chua and J.K. Sheehan. Univ. ofNorth Carolina at Chapel Hill.D430 659.15 Presence of biomolecules in airway mucusimpedes absorption of liquid across porcine tracheal epithelium.S.T. Ballard and J.L. Cooper. Univ. of South Alabama.D431 659.16 Functional effects of carbon nanotubes onairway epithelial cells. A. Banga, F.A. Witzmann and B.L.Blazer-Yost. Indiana Univ. Purdue Univ. Indianapolis andIndiana Univ. Sch. of Med.660. LUNG PHYSIOLOGY: DEVELOPMENT ANDPLASTICITYPosterSUN. 7:30 AM—WASHINGTON CONVENTION CENTER, EXHIBITHALL ABCPresentation time: 12:45 PM-3:00 PMD432 660.1 Temporal-spatial expression of alpha5nicotinic acetylcholine receptor subunits during mouse lungorganogenesis. J.L. Porter, B.R. Bukey, A.J. Geyer and P.R.Reynolds. Brigham Young Univ.D433 660.2 Vitamin D receptor deletion leads to an asthmaphenotype. V.K. Rehan, Y. Li, C. Kovacs and J. Torday. LABioMed, Torrance and Mem. Hosp. of Newfoundland, Canada.D434 660.3 VEGF family growth factor ratio is abnormal inbronchopulmonary dysplasia. S.J. Bilko, L. Xiang, L. Liu andP.G. Lloyd. Oklahoma State Univ.D435 660.4 Aspirin therapy enhances lung alveolarizationin newborn pups exposed to neonatal hyperoxia. R.D. Britt,M. Velten, L.D. Nelin and L.K. Rogers. Nationwide Children’sHosp., Columbus.D436 660.5 Newborn ovine pulmonary vascular smoothmuscle cell proliferation occurs independent of plateletactivating factor receptor activation. L.S. Renteria, J.U. Rajand B.O. Ibe. LA BioMed at Harbor-UCLA Med. Ctr. and Univ.of Illinois at Chicago.D437 660.6 Embryonic over-expression of rage in mouselung causes an imbalance between apoptosis and proliferationleading to severe lung hypoplasia. J.A. Stogsdill, M.P. Stogsdilland P.R. Reynolds. Brigham Young Univ.D438 660.7 rhCC10 treatment modulates the pro- and antiinflammatory profi le in the immature lung. T. Hubert, J. Wu, Y.Park, K. Kato, K. Kimura, T. Shaffer, S. Eguchi, K.C. Kim andM.R. Wolfson. Temple Univ, and A.I. duPont Hosp. for Children,Wilmington, DE.D439 660.8 Dynamic interplay between serum responsefactor and Purβ modulates human pulmonary myofi broblastdifferentiation. S. Hariharan and A.R. Strauch. Davis Heart &Lung Res. Inst., Columbus.D440 660.9 Intrapulmonary shunt pathways are recruitedby hypoxia and beta agonists in juvenile swine. M.L. Bates, J.E.Jacobson, A.S. Sobakin, T.A. Hacker and M.W. Eldridge.Univ. of Wisconsin-Madison.D441 660.10 Limit of compensatory lung growth was reachedfollowing 70% resection in adult canine lung. P. Ravikumar,D.J. Bellotto, A.S. Estrera, R.L. Johnson, Jr. and C.C. W.Hsia. Univ. of Texas Southwestern Med. Ctr.D442 660.11 Quantifying in vivo stimuli for postpneumonectomyalveolar growth: contributions from increasedperfusion and delayed lung expansion. P. Ravikumar, D.Bellotto, A.S. Estrera, R.L. Johnson, Jr. and C.C. W. Hsia.Univ. of Texas Southwestern Med. Ctr.D443 660.12 Modeling tissue changes in the aging lung usingtwo mouse strains. J. Fallica, W. Mitzner and C. Tankersley.Johns Hopkins Bloomberg Sch. of Publ. Hlth.661. MOLECULAR MECHANISMS AND GENETICSOF HYPERTENSION (POSTERS)PosterSUN. 7:30 AM—WASHINGTON CONVENTION CENTER, EXHIBITHALL ABCPresentation time: 12:45 PM-3:00 PMPHYSIOLOGYD444 661.1 In vivo bioluminescence imaging reveals a prehypertensivesurge of nuclear factor-κB activity in the subfornicalorgan during slow-pressor angiotensin-II hypertension. C.N.Young, S.D. Butler, R.V. Sharma and R.L. Davisson. CornellUniv. and Weill Cornell Med. Col.D445 661.2 Microglial activation by the brain reninangiotensinsystem. P. Shi, J.L. Grobe, F.A. Desland, M.K.Raizada and C. Sumners. Univ. of Florida and Univ. of Iowa.D446 661.3 Transgenic expression of CGRP receptorsubunit RAMP1 in nervous system improves autonomicregulation and prevents angiotensin II hypertension. R.Sabharwal, F.M. Abboud, A.F. Russo and M.W. Chapleau.Univ. of Iowa and VA Med. Ctr.D447 661.4 Long-term induction of heme oxygenaseameliorates angiotensin II-dependent hypertension in SpragueDawley rats transduced with HO1-lentiviral construct. N. Puri,L. Vanella, K. Sodhi, J. Cao, D.H. Kim, K. Inoue, J. Quilleyand N.G. Abraham. Univ. of Toledo, Chinese PLA Gen. Hosp.,Beijing and New York Med. Col.D448 661.5 Epoxides attenuate adipogenesis in humanmesenchymal stem cells via activation of heme oxygenaseadiponectinpathways. D.H. Kim, L. Vanella, N. Puri, J.R. Falck,M.L. Schwartzman and N.G. Abraham. Univ. of Toledo, Univ.of Texas Southwestern Med. Ctr. and New York Med. Col.D449 661.6 HO-1 induction preserves ferritin functionimproving insulin sensitivity via AKT/AMPK signaling indiabetic mice. E. Foglio, K. Sodhi, N. Puri, D. Kim, L. Vanella,R. Rezzani, L.F. Rodella and N.G. Abraham. Univ. of Brescia,Italy and Univ. of Toledo.D450 661.7 HO-1 involvement in iron homeostasis in liverof obese mice. G. Favero, K. Sodhi, N. Puri, D. Kim, L. Vanella,R. Rezzani, L.F. Rodella and N.G. Abraham. Univ. of Brescia,Italy and Univ. of Toledo.D451 661.8 Delivery of endothelial progenitor cells derivedfrom consomic SS-13BN/Mcwi donor rats reduces diastolicdysfunction in hypertensive SS/MCWi recipients. S.J. Parkerand A.S. Greene. Med. Col. of Wisconsin.SUN201