SUNDAY, APRIL 10 Across Societies â Experimental Biology

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PHYSIOLOGYD85 639.2 Alterations in hepatic tumor cell colonizationduring obesity. H.A. O’Leary, A. Kothur, A.G. Goodwill, J.C.Frisbee and R.W. Brock. West Virginia Univ.D86 639.3 Ischemia-reperfusion decreases hydrogensulfi de production in the kidney. K. O, G. Prathapasinghe, N.Wu and Y.L. Siow. Univ. of Manitoba and Agr. and Agri-FoodCanada, Winnipeg.D87 639.4 Effects of protein kinase C broad spectruminhibitor Gö 6983 on real-time blood nitric oxide and hydrogenperoxide release in femoral artery/vein ischemia andreperfusion. K.D. Bartol, K-A. Perkins, Q. Chen and L.H.Young. Philadelphia Col. of Osteo. Med.D88 639.5 Soluble guanylate cyclase activation preventspostischemic infl ammation in wild type and heme oxygenase-1KO mice. W.Z. Wang, A.W. Jones, M. Wang, M.Y. Zuidema, W.Durante and R.J. Korthuis. Univ. of Missouri-Columbia.D89 639.6 Excess Ca 2+ enhances ROS generation frominhibited complex III with FADH 2-linked substrate but notNADH-linked substrate. M. Aldakkak, D.F. Stowe, R.K. Dash,M.L. Riess and A.K. S. Camara. Med. Col. of Wisconsin.D90 639.7 Role of reactive oxygen species in postischemicleukocyte rolling and adhesion in male and female plasminogenactivator inhibitor type-1 knockout mice. M. Wang, W. Fay andR.J. Korthuis. Univ. of Missouri-Columbia.D91 639.8 Neuroprotective mechanisms of cerium oxidenanoparticles. W. Mosenthal, M.D. Nieves, A. Beideck, J.S.Erlichman and A.Y. Estevez. St. Lawrence Univ., NY.D92 639.9 Pharmacological postconditioning byintracoronary adenosine in a porcine model of acute myocardialinfarction. M. te Lintel Hekkert, S. Tel, D. Merkus, P.W. Serruys,W.J. van der Giessen and D.J. Duncker. Erasmus Med. Ctr.,Rotterdam.D93 639.10 Antioxidant diet is not effective in kidneyischemia/reperfusion injury. S.R. Inman, T. Hayes, Y. Slyvkaand F.V. Nowak. Ohio Univ.D94 639.11 Chronic resveratrol treatment alleviatesmyocardial ischemia injury in a hypertensive model. K.K.Durham, C.S. Smith and J.W. E. Rush. Univ. of Waterloo,Canada.D95 639.12 Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, infl ammatoryresponse, and cell death. S. Batkai, P. Mukhopadhyay, B.Horvath, M. Rajesh, G. Hasko, D.A. Wink and R. Mechoulam.NIAAA and NCI, NIH, UMDNJ, Newark and Hebrew Univ. ofJerusalem.D96 639.13 Effect of hyponatremia in isolated rat hearts. D.Lee, R. Quarrie, J.L. Zweier and J.A. Crestanello. Ohio StateUniv.D97 639.14 Peroxynitrite produced during cardiacischemia-reperfusion injury induces nitration of mitochondrialvoltage-dependent anion channel. M. Yang, A.K. S. Camara,W-M. Kwok, B.T. Wakim, A.K. Gadicherla, M. Aldakkak, A.D.Boelens, J.S. Heisner and D.F. Stowe. Med. Col. of Wisconsinand VA Med. Ctr.D98 639.15 Catecholamines and high calcium increasethe susceptibility of the isolated rabbit heart to ischemia- andreperfusion-induced ventricular tachyarrhythmias. H. Clements-Jewery and C. Tanga. West Virginia Sch. of Osteo. Med.D99 639.16 Enhancing complement control on theendothelial barrier protects kidney allografts by modulatingimmune response. S. Pushpakumar, G. Perez-Abadia, C.Soni, T. Fensterer and C. Maldonado. Univ. of Louisville.D100 639.17 Cardiolipin degradation during cardiacischemia reperfusion injury: partial restoration by ranolazine.A.K. Gadicherla, A.K. S. Camara, M. Yang and D.F. Stowe.Med. Col. of Wisconsin.D101 639.18 Membrane enhanced complement controlreduces endothelial cell activation and injury. T.M. Fensterer,P. Patibandla, S. Pushpakumar, G. Perez-Abadia, C. Soni, P.Bauer and C. Maldonado. Univ. of Louisville and EndoProtechInc., Louisville.D102 639.19 ECHDC2, a novel mitochondria proteinis abundantly expressed in SS rat hearts: implications forischemia/reperfusion injury J. Du, T. Guan, Q. Yang, H. Xu, S.Welak, K.A. Prichard, Jr., A.K. S. Camara and Y. Shi. Med.Col. of Wisconsin.D103 639.20 Resveratrol improves renal blood fl ow andmicrocirculation in the kidney during experimental septic shockin mice. J.H. Holthoff, Z. Wang, K.A. Seely and P.R. Mayeux.Univ. of Arkansas for Med. Sci.D104 639.21 Role of CD4 + T cells in reperfusion-inducedvascular injury. M.Y. Zuidema, Y. Park, Y. Zhang, J. Wu and C.Zhang. Univ. of Missouri Columbia Sch. of Med.D105 639.22 Effect of topical application of cyanide andnitroglycerin on local oxygen consumption at rest and following1 minute of ischemia in the rat spinotrapezius muscle. W.H.Nugent, A.S. Golub, B.K. Song and R.N. Pittman. VirginiaCommonwealth Univ.640. HYPERTENSIONPosterSUN. 7:30 AM—WASHINGTON CONVENTION CENTER, EXHIBITHALL ABCPresentation time: 12:45 PM-3:00 PMSUNDAYD106 640.1 Skeletal muscle metaborefl ex overactivity ismediated by the TRPv1 receptor in spontaneously hypertensiverats. M. Mizuno, M.N. Murphy, J.H. Mitchell and S.A. Smith.Univ. of Texas Southwestern Med. Ctr.D107 640.2 Reactive oxygen species mediate agonistinducedTRPC6 activation in vascular smooth muscle cells.Y. Ding, M. Ding, S.M. Graham, I. Akopova, S. Muallem, L.Birnbaumer and R. Ma. Univ. of North Texas Hlth. Sci. Ctr.,NIDCR, NIH and NIEHS, NIH, Research Triangle Park.D108 640.3 Endothelin B receptor-mediated activation ofNADPH oxidase alters norepinephrine-related gene expressionin PC-12 cells. C.L. Henley, X. Cao and D.L. Kreulen. MichiganState Univ. and Weill Cornell Med. Col.D109 640.4 Augmented angiotensin II signalling inresistance vessels from smooth muscle specifi c dominantnegative PPARG transgenic mice. M. A.C. Sepulveda, P.Ketsawatsomkron and C.D. Sigmund. Univ. of Iowa.D110 640.5 Exercise pressor refl ex induced FOS expressionis co-localized with neurons containing neuronal nitric oxidesynthase in the nucleus tractus solitarius. M.N. Murphy, M.Mizuno and S.A. Smith. Univ. of Texas Southwestern Med.Ctr.D111 640.6 Intrathecal kynurenate decreases arterialpressure in conscious DOCA-salt hypertensive rats.B. Veitenheimer and J. Osborn. Univ. of Minnesota,Minneapolis.188
SUNDAYD112 640.7 Contribution of oxidant stress to endothelialdysfunction in middle cerebral arteries of fawn-hoodedhypertensive rats. B.D. Weinberg and J.H. Lombard. Med.Col. of Wisconsin.D113 640.8 Cardiac sympathetic nerves do not contributeto AngII-salt hypertension. D.M. Hirsch and J. Osborn. Univ.of Minnesota Med. Sch.D114 640.9 Protein phosphatase 1(PP1) binds to WNK4and regulates WNK4 interaction with SGK1 and c-Src. P. Yue,D. Lin and W. Wang. New York Med. Col.D115 640.10 Peripheral chemoreceptor inputs contributeto the development of high blood pressure in spontaneouslyhypertensive rats. A.P. L. Abdala, J.F. R. Paton and A.Gourine. Univ. of Bristol and University Col. London.D116 640.11 Augmented S-nitrosylation contributes toimpaired relaxation in angiotensin II hypertensive mouse aorta:role of thioredoxin reductase. H. Choi and R.C. Webb. Med.Col. of Georgia.D117 640.12 Treatment with tumor necrosis factor-? blocker,etanercept, attenuates the angiotensin II-induced hypertensiveresponse in eNOS knockout mice C. Whiting, A. Castillo, D.Agarwall, J. Francis and D. Majid. Tulane Sch. of Med. andLSU Sch. of Vet. Med.D118 640.13 Urinary renin excretion is increased in chronicangiotensin II-infused hypertensive rats. L. Liu, D.M. Seth,L.G. Navar and M.C. Prieto. Tulane Univ. Sch. of Med. andHyperten. and Renal Ctr. of Excellence, New Orleans.D119 640.14 Mechanisms of aortic stiffness in salt-sensitivehypertension. W.E. Rodriguez-Alvarez, P. Kumar, R. Lawal,C. Harris, B. Williams, A. S. O. Adeagbo, S.C. Tyagi and I.G.Joshua. Univ. of Louisville and Commonwealth Med. Col., PA.D120 640.15 The effects of an herbal extract SPOO2P onvascular relaxation responses. W.E. Rodriguez-Alvarez, R.Lawal, N. Perumal, C. Harris, B. Williams, A. Adeagbo andI.G. Joshua. Univ. of Louisville and Commonwealth Med. Col.D121 640.16 Endothelial damage refl ected by circulatingendothelial cells in young patients with latent or manifesthypertension. N.P. Lyamina, S.V. Lyamina, V.N. Senchikhin,K.A. Dodina, E.B. Manukhina and H.F. Downey. Res. Inst. ofCardiol., Saratov, Moscow State Univ. of Med. and Dent., Inst.of Gen. Pathol. and Pathophysiol., Moscow and Univ. of NorthTexas Hlth. Sci. Ctr.D122 640.17 Evidence that cell-free hemoglobin induces ratpulmonary artery smooth muscle cell proliferation by decreasingnuclear cyclic AMP response element binding protein by amechanism(s) other then oxidative stress. D. Irwin, C. Lisk, I.Connor, E. Forchielli, C. Garat-Carter and D. Klemm. Univ. ofColorado Denver, Aurora.D123 640.18 Cortisol and dexamethasone-induced hypertensionincreased intramuscular nitric oxide levels in fetalprogrammed hypertensive rats. S. Fabris, T.C. Tai and D.MacLean. Northern Ontario Sch. of Med. and Laurentian Univ.,Canada.D124 640.19 Orchidectomy reduced abdominal aortarelaxation response to androgens in Sprague-Dawley rats feda high-salt diet. A.K. Oloyo, O.A. Sofola, C.N. Anigbogu, R.R.Nair and V. Harikrishnan. Univ. of Lagos, Nigeria, Sree ChitraTirunal Inst. for Med. Sci. and Technol., India.D125 640.20 Inhibition of nitric oxide-GABA pathway byreactive oxygen species in the rostral ventrolateral medullacauses sympathoexcitation in SHRSP. K. Shinohara, Y.Hirooka, T. Kishi and K. Sunagawa. Kyushu Univ. Grad. Sch.of Med. Sci., Japan.PHYSIOLOGYD126 640.21 Inhibition of reactive oxygen species in rostralventrolateral medulla augments sympathoexcitatory effectsfrom the paraventricular nucleus of the hypothalamus inspontaneously hypertensive rats. M. Nishihara, Y. Hirooka, T.Kishi and K. Sunagawa. Kyushu Univ. Grad. Sch. of Med. Sci.,Japan.D127 640.22 A pancreatic source of protease activity in thespontaneously hypertensive rat and its reduction during shorttermfood reduction. A. Chan and G.W. Schmid-Schönbein.UCSD.D128 640.23 2-Kidney 1-clip hypertension restores impairedvascular relaxation in Dahl salt-sensitve rats. A.M. Beyer andJ.H. Lombard. Med. Col. of Wisconsin.D129 640.24 Gastrin stimulates Na, K-ATPase phosphorylationand endocytosis via PI3 kinase-mTOR-S6 kinase andPKC pathways in immortalized renal proximal tubule cells T.Liu and P.A. Jose. Children’s Natl. Med. Ctr.D130 640.25 Increased blood pressure after acuteadministration of low lead concentration depends on the SRAactivation. D.V. Vassallo, M.R. Simões, R.F. Ribeiro Júnior,M.V. A. Vescovi, H.C. de Jesus, A.S. Padilha, I. Stefanon, M.Salaices and M. Fioresi. Fed. Univ. of Espírito Santo, Braziland Autonomous Univ. of Madrid.D131 640.26 In vitro ascorbic acid treatment decreasesresistance-sized mesenteric artery myogenic reactivity inpregnant rats with reduced uterine perfusion pressure. R.J.Ramirez, J.J. Reho, J. Peck and J. Novak. Univ. of Akron andWalsh Univ., OH.D132 640.27 Injection of AMP-activated protein kinaseactivator AICAR acutely reduces blood pressure inspontaneously hypertensive rats. R.J. Ford, S. Teschke andJ.W. E. Rush. Univ. of Waterloo, Canada.D133 640.28 Altered uterine artery reactivity from pregnantrats with reduced uterine perfusion pressure. J.J. Reho, J.Novak and R.J. Ramirez. Univ. of Akron and Walsh Univ.,OH.D134 640.29 TNF alpha does not mediate functional changesin corpora cavernosa from DOCA-salt rats. F. Carneiro, Z.N.Carneiro, F. Giachini, V.V. Lima, R.C. Webb and R.C. Tostes.Med. Col. of Georgia and Univ. of São Paulo, Ribeirão Preto.D135 640.30 Altered phenylephrine-induced vascularcontractility and reduced endothelial function during the onsetof renal wrap hypertension. H. Al-Azawi, S. Gordon, C.A.Northcott and A.K. L. Banes-Berceli. Oakland Univ., MI andMichigan State Univ.D136 640.31 Increasing pressure pulse wave velocitydoes not increase aortic pulse pressure in the elderly. M.W.Mohiuddin, G.A. Laine, W.I. Douglas and C.M. Quick. TexasA&M Univ. and Univ. of Texas Hlth. Sci. Ctr. at Houston.D137 640.32 Scavenging peroxinitrite attenuatesangiotension II-induced hypertension in rats. M.C-W. Chavisand A. Yasir. Tulane Univ.D138 640.33 Higher central and brachial artery systolic andpulse pressure in black overweight/obese adolescents: relationwith aortic stiffness and pressure wave refl ection. G.L. Pierce,H. Zhu, I. Stallmann-Jorgensen, Y. Huang, D. Guo, I. Edet, K.Darracott and Y. Dong. Med. Col. of Georgia.D139 640.34 Abnormal autonomic regulation of the immunesystem in genetic hypertension. S.C. Harwani, M.W. Chapleauand F.M. Abboud. Univ. of Iowa.D140 640.35 Fetal programming of vascular dysfunction.J.A. Thompson, R. Gros, B.S. Richardson and T.R. H.Regnault. Univ. of Western Ontario and Robarts Res. Inst.,London, Canada.SUN189
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SUNDAY, APRIL 10 Across Societies â Experimental Biology

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SUNDAY, APRIL 10 Across Societies â Experimental Biology