BIOCHEMISTRY495. ANATOMY EDUCATION: COMPUTER-ASSISTEDLEARNINGPosterSUN. 7:30 AM—WASHINGTON CONVENTION CENTER, EXHIBITHALL ABCPresentation time: 12:30 PM-2:00 PMC89 495.1 Online learning program for regional anatomy:usage and monitoring through Google Analytics. L. Filgueira,P. Groscurth and L. Slomianka. Univ. of Western Australiaand Univ. of Zurich.C90 495.2 Automated system for on-demand generationof photorealistic structure-specifi c interactive anatomicalreconstructions. M.J. Pescitelli, S. Huntley, S. Landers, E.Theiss, C. Lilagan and M. Doyle. Univ of Illinois at ChicagoCol. of Med., Buonacorsi Fndn., Wheaton and Iomas Res. LLC,Wheaton, IL.C91 495.3 Dyad pedagogy and the application of videoeducation in anatomy. A.D. Blumenberg, V. Trivigno, H. Khanand S. Marquez. SUNY Downstate Med. Ctr.C92 495.4 Creation of a digital atlas for ultrasoundguided regional nerve blocks. K. Milne, M. Johnson and S.Ganapathy. Univ. of Western Ontario.C93 495.5 Interdisciplinary media study of anatomicaleducation via virtual worlds. M.J. Devlin and T.D. Wilson. Univ.of Western Ontario.C94 495.6 Use of a digital 3D brain model as anintermediate step in learning spatial anatomy. D.N. Brewer, S.de Ribaupierre and T.D. Wilson. Univ. of Western Ontario.496. ANATOMY EDUCATION: TEACHING METHODSAND INNOVATIONSPosterSUN. 7:30 AM—WASHINGTON CONVENTION CENTER, EXHIBITHALL ABCPresentation time: 12:30 PM-2:00 PMC95 496.1 Texas Tech System for student peer teaching inthe anatomy laboratory. V. Lee and B. Vidic. Texas Tech Univ.Hlth. Sci. Ctr.C96 496.2 Taking successful pilot program to scale:evolution of team-based learning in anatomy program. N.Vasan and D. DeFouw. UMDNJ-New Jersey Med. Sch.C97 496.3 Teaching the millennial generation of medicalstudents. A.R. Severson. Univ. of Minnesota Med. Sch.,Duluth.C98 496.4 Critical thinking in the cadaver lab: determiningthe cadaver’s cause of death. M.T. Bee, J.M. Montante and M.Ottenbreit. Oakland Univ. William Beaumont Sch. of Med. andUniv. of Detroit Mercy.C99 496.5 Boning up in anatomy: engaging learningapproaches. M.T. Bee and G. Grabowski. Oakland Univ.William Beaumont Sch. of Med. and Univ. of Detroit Mercy.C<strong>10</strong>0 496.6 Can virtual anatomy lab be an alternative ofcadaver-based anatomy lab? S. Chowdhury and R. Lovely.St Louis Community Col., Wildwood and Missouri State Univ.C<strong>10</strong>1 496.7 A multi-faceted approach to teachingembryology within an integrated human structure course. G.E.Harmon, W. Pawlina and N. Lachman. Mayo Med. Sch.C<strong>10</strong>2 496.8 Creating virtual fl ashcards in the anatomicalsciences using MemoryLifter technology. V. Lyons and N.McNulty. Dartmouth Med. Sch.C<strong>10</strong>3 496.9 Using podcasting to promote learning ofneuroanatomy. C.A. Webber and J. Tong. Univ. of Alberta.497. ANATOMY EDUCATION: UNDERGRADUATEPosterSUN. 7:30 AM—WASHINGTON CONVENTION CENTER, EXHIBITHALL ABCPresentation time: 12:30 PM-2:00 PM<strong>SUNDAY</strong>C<strong>10</strong>4 497.1 Focused preparation of anatomy and physiologyinstructors for the undergraduate college and university setting.R.A. Crocker. New York Chiropractic Col.C<strong>10</strong>5 497.2 Remediation trends in an undergraduateanatomy course. A.F. Schutte. Indiana Univ.C<strong>10</strong>6 497.3 Incorporating anatomical imaging intoundergraduate anatomy labs. J. Jackson and H. Ali. Univ. ofNorth Dakota.C<strong>10</strong>7 497.4 Research as a transformative learning tool inan undergraduate histology course. M.B. Vaughan. Univ. ofCentral Oklahoma.C<strong>10</strong>8 497.5 The effect of a Clearing of the Way ceremonyon students’ attitudes to dissection. H.D. Nicholson, T. Barrettand H. Martyn. Univ. of Otago, New Zealand.138
<strong>SUNDAY</strong>BIOCHEMISTRYBiochemistry and Molecular <strong>Biology</strong>498. ABERRANT DNA REPAIR, GENOMICINSTABILITY AND CANCERPosterSUN. 7:30 AM—WASHINGTON CONVENTION CENTER, EXHIBITHALL ABCPresentation time: 1:05 PM-2:35 PMB1 498.1 Transcriptional response to loss of RNase H2activity in Saccharomyces cerevisiae. M.E. Arana, R.T. Kerns,P.R. Bushel and T.A. Kunkel. NIEHS, NIH, Research TrianglePark.B2 498.2 Inhibition of DNA helicase activity determinedby SPR. W.M. David, S.M. Kerwin and M.J. Decker. TexasState Univ., San Marcos and Univ. of Texas at Austin.B3 498.3 Polymorphic variants of human DNAglycosylase NEIL2 and lung cancer susceptibility. S. Dey, A.K.Maiti, M.L. Hegde, P.M. Hegde, B. Shen, I. Boldogh, J. Xie, V.Cardenas and T.K. Hazra. Univ. of Texas Med. Branch, City ofHope and Indiana Univ.-Purdue Univ. Indianapolis.B4 498.4 Mitotic analysis as a measure of genomicinstability during the propagation of human pluripotentstem cells. V. Fields, M.J. Riggs and R.R. Rao. VirginiaCommonwealth Univ.B5 498.5 A novel role of RGS6 in oncogenic Ras-inducedcellular transformation. J. Huang, J. Yang, J. Hagen, D. Quelleand R. Fisher. Univ. of Iowa.B6 498.6 Regulation and function of the TAZ transcriptionco-activator. Q. Lei. Sch. of Med., Fudan Univ., People’sRepublic of China.B7 498.7 The role of recombination genes duringtelomere maintenance in telomerase-defi cient tumors andprimary cells. T.A. Morrish, V. Behera, M.A. Strong and C.W.Greider. Johns Hopkins Univ.B8 498.8 Syzgium guineensis extracts display cellspecifi c anticancer properties. A. Nkembo, N.S. Lamango,H. Gokham, L. Ayuk-Takem, R. Duverna, R. Marijani and B.Abonyo. Florida A&M Univ.B9 498.9 Studies on the utilization of a thioaptamer forthe rescue of p53 and its mutants. L.P. Rangel, A. P.D. AnoBom and J.L. Silva. Fed. Univ. of Rio de Janeiro and OswaldoCruz Fndn., Rio de Janeiro.B<strong>10</strong> 498.<strong>10</strong> Homologous recombination independent rolefor BRCA2 in blocking stalled replication fork degradation byMRE11. K. Schlacher, N. Christ and M. Jasin. Mem. Sloan-Kettering Cancer Ctr. and UCLA.B11 498.11 RNA polymerase II CTD-associated DNA repairand recombination. T. Winsor, C. Bennett and A. Greenleaf.Duke Univ.499. DNA DAMAGE SIGNALINGPosterSUN. 7:30 AM—WASHINGTON CONVENTION CENTER, EXHIBITHALL ABCPresentation time: 1:05 PM-2:35 PMB12 499.1 In vitro studies of MutSalpha protein inmismatch excision repair and DNA damage signaling. H. Gengand P. Hsieh. NIDDK, NIH.B13 499.2 Loss of p300 induces a rapid aging phenotypeand blunts ATM-initiated DNA damage response. S. Jain, C.Rodrigues, J. Wei and N.H. Bishopric. Univ. of Miami.500. DNA REPAIR MECHANISMSPosterSUN. 7:30 AM—WASHINGTON CONVENTION CENTER, EXHIBITHALL ABCPresentation time: 1:05 PM-2:35 PMB14 500.1 Identifi cation of Escherichia coli processingactivities for covalent topoisomerase-DNA complexes. S. Aedoand Y-C. Tse-Dinh. New York Med. Col.B15 500.2 Dissecting cellular inter-strand crosslink repairpathways through the recruitment kinetics of Fanconi anemiaproteins to localized ICLs. M.A. Bellani, P. Muniandy, M.Paramasivam, A. Smogorzewska, W. Wang, J. de Winterand M.M. Seidman. NIA, NIH, Baltimore, Dana Farber Inst.,Rockefeller Univ. and Free Univ. Med. Ctr., Amsterdam.B16 500.3 Conformational explorations into DNApolymerase X from African swine fever virus in the presenceof oxoG lesions. J. Bogdanovic, Z. Barbati, T. Schlick, K.Arora and B.A. S. Benitez. Marymount Manhattan Col., Univ.of Copenhagen, NYU and Univ. of Michigan.B17 500.4 Developing reporter systems to monitor thestructural dynamics of MutS, a DNA mismatch repair protein C.Doucette, M. Hingorani and F.N. Biro. Wesleyan Univ.B18 500.5 NEIL1’s common interaction peptide acts asdominant negative inhibitor of NEIL1-initiated base excisionrepair of oxidized bases: potential for adjuvant cancer therapy.M.L. Hegde, P.M. Hegde, T.K. Hazra, I. Boldogh and S. Mitra.Univ. of Texas Med. Branch.B19 500.6 Deciphering the origin of multiple substratespecifi city of the repair enzyme, AlkB N. Jayanth, N. Ogiralaand M. Puranik. Natl. Ctr. for Biol. Sci., Bangalore.B20 500.7 A structural hinge in the eukaryotic DNA repairglycosylase, MutY homologue, mediates catalytic activity andinteractions with the Rad9-Rad1-Hus1 checkpoint complex P.J.Luncsford, D-Y. Chang, G. Shi, J. Bernstein, A. Madabushi,D.N. Patterson, A-L. Lu and E.A. Toth. Univ. of Maryland Sch.of Med.B21 500.8 Crystal structure of human thymine DNAglycosylase bound to a DNA substrate analog reveals themolecular basis of specifi city and catalysis. A. Maiti, E.Pozharski and A.C. Drohat. Univ. of Maryland Sch. of Med.and Sch. of Pharm.B22 500.9 APE1/Ref-1: a multi-functional protein thatprotects neurons against amyloid beta toxicity. A.K. Mantha,J.R. Perez-Polo and S. Mitra. Univ. of Texas Med. Branch.B23 500.<strong>10</strong> Molecular clues to alkylating agent-induced celldeath and drug resistance. M. Fried, G-M. Li and F. Odago.Univ. of Kentucky.B24 500.11 E. coli UmuD conformational dynamics inresponse to DNA damage. J. Ollivierre, Q. Huang, D. Budiland P.J. Beuning. Northeastern Univ.B25 500.12 A novel role for the VapB-2 antitoxin ofnontypeable Haemophilus infl uenzae in genomic stabilityfollowing oxidative stress. D. Ren, S.D. Cline, C. Bell III andD.A. Daines. Mercer Univ. Sch. of Med.SUN139