SUNDAY, APRIL 10 Across Societies – Experimental Biology

PHYSIOLOGYD249 645.11 Effects of aging on cardiac autonomic controlin female rats – role of physical training. G. C.S. V. Tezini, J.M.Porto and H. C.D. Souza. Sch. of Med. of Ribeirão Preto, Univ.of São Paulo.D250 645.12 Regulation of store operated calcium channelsby μ-opioid receptor activation in mammalian intracardiacneurons. T. Bonds and J. Cuevas. Univ. of South Florida.D251 645.13 Postsynaptic crosstalk between excitatory(NMDA) and inhibitory (GABAA) receptors in neurosecretoryneurons of the hypothalamic supraoptic nucleus. E. Potapenko,V.C. Biancardi, R.M. Florschutz and J.E. Stern. Med. Col. ofGeorgia.D252 645.14 Nucleus ambiguus neurons are activated byacupuncture: relation to acetylcholine and enkephalin. Z-L.Guo and J.C. Longhurst. Univ. of California, Irvine.D253 645.15 Age-related decreases in barorefl ex sensitivityand circadian variation of blood pressure and heart rate aremediated by centrally produced hydrogen peroxide. B. Erdos,H. Frimpong, M.A. Whidden, N. Kirichenko and N. Tumer. VAMed. Ctr. and Univ. of Florida.D254 645.16 Effects of Bacillus anthracis lethal and edematoxins on functional indices of sympathetic nerve dischargeregulation. A.A. Garcia, R.J. Fels and M.J. Kenney. KansasState Univ.D255 645.17 Parasymapthetic and sympathetic contributionsto enhanced cardiac barorefl ex gain after exposure to chronicintermittent hypoxia in rats. A.Q. Silva and A.M. Schreihofer.Univ. of North Texas Hlth. Sci. Ctr.646. NEURAL MECHANISMS IN CARDIOVASCULARDISEASEPosterSUN. 7:30 AM—WASHINGTON CONVENTION CENTER, EXHIBITHALL ABCPresentation time: 12:45 PM-3:00 PMD256 646.1 Brain-derived neurotrophic factor directlymodulates cardiac ventricular myocyte function. N. Feng, S.Huke, S. Shi, A. Takeshi, N. Kaludercic, G. Tomaselli, D.Bers and N. Paolocci. Johns Hopkins Sch. of Med., VanderbiltUniv. and Univ. of California, Davis.D257 646.2 Substance P receptor blockade attenuatesoxidative stress, endotoxemia and cardiac dysfunction in Mgdeficient rats. J.H. Kramer, C.F. Spurney, I-T. Mak, M. Iantorno,A. Komarov and W.B. Weglicki. George Washington Univ. andChildren’s Natl. Med. Ctr.D258 646.3 After myocardial infarction, rats displayneophobia and altered forebrain metabolic activation inresponse to locus coeruleus stimulation J. Glasgow, A.Samarel, Y. Koshman, D. Klein and K. Scrogin. Loyola Univ.Chicago, Maywood.D259 646.4 Effect of statin therapy on resting sympatheticnerve activity and oxidative stress in patients with heart failure.S.H. Deo, L.C. Vianna, A. Kim, A. Chockalingam, M.C.Zimmerman, I.H. Zucker and P.J. Fadel. Univ. of Missouri-Columbia and Univ. of Nebraska Med. Ctr.D260 646.5 Cardiac spinal deafferentation reduces thesusceptibility to sustained ventricular tachycardia in consciousrats by reducing cardiac metabolic demand. H.L. Lujan, S.Krishnan and S.E. DiCarlo. Wayne State Univ. Sch. of Med.D261 646.6 Role for the medial amygdala in mediatinghypertenion in a neurogenic mouse model. P. Davern, K.Jackson, T-P. Nguyen-Huu and G. Head. Baker IDI Heart &Diabetes Inst., Melbourne.D262 646.7 Involvement of the autonomic nervous systemin cardiovascular function of monosodium glutamate-inducedobese rats. M. Karlen-Amarante, N.V. Cunha, O. Andradeand M.C. Martins-Pinge. State Univ. of Londrina, Brazil.D263 646.8 Hindlimb unloading results in an increasedpredisposition to cardiac arrhythmias and changes in leftventricular connexin43 expression. J.A. Moffitt, K.C. Welliver,A.J. Jepson and M.K. Henry. Des Moines Univ.D264 646.9 Epithelial sodium channels contribute to theblunted sensitivity of aortic baroreceptors in chronic heartfailure rats. H. Tu, T. Thai, R. Muelleman and Y-L. Li. Univ. ofNebraska Med. Ctr.D265 646.10 Effect of pyridostigmine on both cardiac functionand remodeling in heart failure rats. R.M. Lataro, C.A. A. Silva,C.M. Prado, M.A. Rossi, R. Fazan, Jr. and H.C. Salgado. Sch.of Med. of Ribeirão Preto, Univ. of São Paulo.D266 646.11 Increased acetylcholine availability in the earlystages of heart failure in rats: effects on cardiac autonomic toneand left ventricular function. D.P. M. Dias, R. Fazan, Jr., H.C.Salgado, T. Beltz and A.K. Johnson. Sch. of Med. of RibeirãoPreto, Univ. of São Paulo and Univ. of Iowa.D267 646.12 Chronic electrical stimulation of the ventrallateral periaqueductal grey evokes a persistent and substantialhypotensive response in spontaneously hypertensive but notnormotensive rats. F.D. McBryde, N. Patel and J.F. R. Paton.Univ. of Bristol and Frenchay Hosp., Bristol.D268 646.13 Distribution and morphology of CGRP- andSP-IR (immunoreactive) axons in the whole-mount atria of FVBmice. L. Li, J. Hatcher, H. Gu and Z. Cheng. Univ. of CentralFlorida Col. of Med. and Univ. of Iowa Col. of Med.D269 646.14 Control of cardiac chronotropy by the nucleusambiguus and dorsal motor nucleus of the vagus: a lighthand on the cardiac tiller. L. Salo, R. McAllen, M. Ambler, S.Kasparov, J.F. R. Paton and T. Pickering. Univ. of Bristol andHoward Florey Inst., Melbourne.647. NEURAL CONTROL IN HUMANSPosterSUN. 7:30 AM—WASHINGTON CONVENTION CENTER, EXHIBITHALL ABCPresentation time: 12:45 PM-3:00 PMSUNDAYD270 647.1 Pressor responses following a spontaneousburst of muscle sympathetic nerve activity: infl uence of ageand sex. L.C. Vianna, E.C. Hart, S.T. Fairfax, N. Charkoudian,M.J. Joyner and P.J. Fadel. Univ. of Missouri-Columbia andMayo Clin.D271 647.2 Sex-related differences in fi ring patterns ofintegrated muscle sympathetic nerve activity in humans. H.Yang, W.H. Cooke, K.S. Reed and J.R. Carter. MichiganTechnol. Univ. and Univ. of Texas at San Antonio.D272 647.3 Estrogen enhances barorefl ex sensitivityin women with low orthostatic tolerance. M.M. Wenner, H.S.Taylor, A.S. Haddadin and N.S. Stachenfeld. John B. PierceLab., New Haven and Yale Univ. Sch. of Med.194