10.04.2016 Views

Sin death and beyond

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

SIN, DEATH AND BEYOND: M.M.NINAN<br />

consequence of developmental processes. During development, the central nervous system<br />

acquires information via endogenous or exogenous factors as well as learning experiences. In<br />

acquiring <strong>and</strong> storing such information, the plastic nature of the central nervous system allows<br />

for the adaptation of existing neural connections in order to accommodate new information <strong>and</strong><br />

experiences, resulting in developmental plasticity.<br />

This form of plasticity that occurs during development is the result of three predominant<br />

mechanisms: synaptic <strong>and</strong> homeostatic plasticity, <strong>and</strong> learning. The underlying principle of<br />

synaptic plasticity is that synapses undergo <strong>and</strong> activity-dependent <strong>and</strong> selective strengthening<br />

or weakening so new information can be stored. In order to maintain balance, homeostatic<br />

controls exist to regulate the overall activity of neural circuits specifically by regulating the<br />

destabilizing effects of developmental <strong>and</strong> learning processes that result in changes of<br />

synaptic strength. By depending largely upon selective experiences, neural connections are<br />

altered <strong>and</strong> strengthened in a manner that is unique to those experiences.<br />

Hebbian Theory is that the persistence or repetition of a reverberatory activity (or "trace") tends<br />

to induce lasting cellular changes that add to its stability is sometimes stated as "Cells that fire<br />

together, wire together" The theory attempts to explain associative or Hebbian learning, in<br />

which simultaneous activation of cells leads to pronounced increases in synaptic strength<br />

between those cells, <strong>and</strong> provides a biological basis for errorless learning methods for<br />

education <strong>and</strong> memory rehabilitation. the theory is also called Hebb's rule, Hebb's postulate,<br />

<strong>and</strong> cell assembly.<br />

(Sensitive Periods in the Development of the Brain <strong>and</strong> Behavior Eric I. Knudsen Journal of<br />

Cognitive Neuroscience 16:8, pp. 1412–1425)<br />

“Experience exerts a profound influence on the brain <strong>and</strong>, therefore, on behavior. When the<br />

effect of experience on the brain is particularly strong during a limited period in development,<br />

this period is referred to as a sensitive period. Such periods allow experience to instruct<br />

11

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!