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Vitamin D and Health

SACN_Vitamin_D_and_Health_report

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Study/Country Population Mean follow up Mean 25(OH)D (nmol/L) Results/comments<br />

Prostate<br />

Meyer et al (2013)<br />

Norway<br />

Albanes et al (2011)<br />

Finl<strong>and</strong><br />

Br<strong>and</strong>stedt et al<br />

(2012)<br />

Sweden<br />

Schenk et al (2014)<br />

USA<br />

Kristal et al (2014)<br />

USA<br />

Shui et al (2012)<br />

USA<br />

Males (n=2106 cases & 2106 controls)<br />

Mean age: 48.2 ± 9.2y<br />

Men in ATBC study (n=1000 cases &<br />

1000 controls)<br />

Median age (IQR): 57 (54-62) y<br />

Men in the Malmö Diet & Cancer Study<br />

(n= 443 cases & 443 controls)<br />

Mean age (y)<br />

Cases: 61.7 (6.4)/Controls: 61.6 (6.4)<br />

Men in the Prostate Cancer Prevention<br />

Trial (n=1695 cases & 1682 controls)<br />

Age: 55+ y<br />

Men in the Selenium & <strong>Vitamin</strong> E<br />

Cancer Prevention Trial (n=1731 cases<br />

& 3203 controls)<br />

Mean age (y)<br />

Cases: 63.5 (±6.1)/Controls:63.3 (±6.5)<br />

Men in the <strong>Health</strong> Professionals Follow<br />

up Study (n=1260 cases & 1331<br />

controls)<br />

Mean age (y): 64.4 (7.8)<br />

Oesophagus <strong>and</strong> stomach<br />

Abnet et al (2010) Adults from 8 cohorts (Cohort<br />

Consortium <strong>Vitamin</strong> D Pooling Project<br />

China, Finl<strong>and</strong>, USA<br />

of Rarer Cancers - VDPP) (n=1065 cases<br />

& 1066 controls)<br />

Median (IQR) age (y)<br />

Cases: 61 (55-67)/Controls: 61 (55-66)<br />

16.1 y (median) Cases: 64.4 ± 22.2<br />

Controls: 62.4 ± 22.3<br />

6.1 y (median) Median (IQR)<br />

Cases: 34.5 (22.7-50)<br />

Controls: 33.6 (21.4-49.1)<br />

7.6 ± 3.5 y Cases – 87.4 (26.4)<br />

Controls – 86.4 (27.3)<br />

Relative risks (95% CI) by 25(OH)D concentration (nmol/L)<br />

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