21.07.2016 Views

Vitamin D and Health

SACN_Vitamin_D_and_Health_report

SACN_Vitamin_D_and_Health_report

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

Genetic polymorphism<br />

Genome<br />

Genotype<br />

Half-life<br />

Heterogeneous<br />

Homeostasis<br />

Homogeneous<br />

Hypercalciuria<br />

Hyperparathyroidism<br />

Lower Reference Nutrient<br />

Intake (LRNI)<br />

Lymphocyte (B <strong>and</strong> T)<br />

Macrophage<br />

Minimal erythemal dose<br />

(MED)<br />

Metabolic bone disease<br />

Metabolites<br />

Monocytes<br />

Osteoblast<br />

Natural variation in a gene, DNA sequence or chromosome.<br />

Full DNA sequence of an organism.<br />

Genetic constitution of an individual as distinct from its expressed<br />

features.<br />

Time required for concentration of a substance in the body to<br />

decrease by half.<br />

Varied in content; composed of different parts.<br />

The process by which the internal systems of the body maintain a<br />

balance despite external conditions.<br />

Having parts which are all similar or which consist of only one<br />

substance.<br />

Elevated calcium in the urine. Defined as urinary calcium excretion<br />

> 250 mg/d in women <strong>and</strong> 275-300 mg/d in men.<br />

Over-activity of the parathyroid gl<strong>and</strong>s that results in high<br />

concentration of parathyroid hormone. This leads to weakening of<br />

the bones through bone resorption to release calcium from the bone.<br />

See Dietary Reference Values.<br />

White blood cells that form part of the body’s immune system. B cells<br />

produce antibodies that neutralise foreign bodies like viruses <strong>and</strong><br />

bacteria; T cells produce substances that directly <strong>and</strong> indirectly induce<br />

the death of infected cells.<br />

A type of white blood cell that forms part of the body’s immune<br />

system. Macrophages engulf invading antigens <strong>and</strong> ultimately<br />

stimulate production of antibodies against the antigen.<br />

Minimum dose of ultraviolet radiation required to produce a just<br />

measurable degree of sunburn or redness. Varies with each individual.<br />

Bone abnormalities usually caused by an imbalance of minerals<br />

(calcium <strong>and</strong> phosphorus) or vitamin D in the body.<br />

Intermediates <strong>and</strong> products of chemical reactions in the body.<br />

A type of white blood cell that, in response to inflammation,<br />

differentiates into macrophages <strong>and</strong> dendritic cells to elicit an<br />

immune response.<br />

Bone cell that synthesises osteoid <strong>and</strong> facilitates its calcification as<br />

part of the processes of skeletal development, maintenance <strong>and</strong><br />

repair.<br />

287

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!