American Materia Medica, Therapeutics and Pharmacognosy

Therapy—Kino is less used than formerly. It may be given whenever there
is excessive secretion or excretion. In inordinate night sweats, either
during convalescence from prostrating disease, or those of phthisis
pulmonalis, it is a useful remedy. In the treatment of polyuria, kino is
advised as an active agent with which to control the excessive output of
water. It is also used in diabetes mellitus, and in protracted watery
diarrheas without pain, characterized by relaxation and flabbiness of
tissues, and general feebleness. It may be prescribed in the diarrhea of
typhoid, also, with good results, especially if hemorrhage be present.
The powder may be blown into the nostrils in epistaxis, and it may be
dusted on ulcers and bleeding surfaces. An injection of a strong solution
is useful in leucorrhea and in other discharges either of a specific or
nonspecific character. It is of some service in pharyngitis, or in
elongated uvula, also in simple acute sore throats.
GRANATUM. Punica granatum.
Synonym-Pomegranate.
CONSTITUENTS—
Pelletierine, a colorless liquid, soluble in twenty parts of cold water,
freely soluble in alcohol. Acted upon by sulphuric, hydrochloric, or
hydrobromic acids, a crystalline salt is formed in each case. With tannic
acid, the tannate of pelletierine is formed, a yellowish powder, odorless,
pungent, astringent.
Dose of the alkaloid, from one-tenth to one-half grain.
Dose of the salts of the alkaloid, from one to five grains.
Extractum Granatum Fluidum. Fluid Extract of Granatum. Dose,
from fifteen to thirty minims.
Physiological Action—Pomegranate has an astringent influence quite
marked, at the same time in full doses it produces evacuation of the
bowel, and in some cases irritation and emesis may be induced. A
decoction of the fresh bark of the root will produce the best results, when
the anthelmintic influence of the agent is desired.
Therapy—It is a specific for the destruction of the tapeworm. Two ounces
of the fresh bark is macerated in two pints of water for twenty-four hours,
when it is then boiled down to one pint. After fasting one day, the patient
Ellingwood’s American Materia Medica, Therapeutics and Pharmacognosy - Page 366