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Introduction to Health Physics: Fourth Edition - Ruang Baca FMIPA UB

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250 CHAPTER 6<br />

gamma per decay. The output data list the integral dose in an infinite medium, per<br />

g · rads<br />

unit of cumulated activity, in units of for each radiation. To convert from<br />

μCi · h<br />

the old system of units found in the MIRD publications <strong>to</strong> the SI system, that is, <strong>to</strong><br />

g · rads kg · Gy<br />

go from <strong>to</strong> , we use the following relation:<br />

μCi · h Bq · s<br />

kg · Gy<br />

Bq · s<br />

kg · Gy<br />

Bq · s<br />

= g · rad<br />

μCi · h ×<br />

−3 kg Gy<br />

10 × 10−2<br />

g rad<br />

4 Bq<br />

s<br />

3.7 × 10 × 3.6 × 103<br />

μCi h<br />

= g · rad<br />

μCi · h × 75.1 × 10−14 . (6.87)<br />

To convert from SI units <strong>to</strong> traditional units:<br />

g · rad<br />

μCi · h =<br />

1 kg · Gy<br />

×<br />

7.51 × 10−14 Bq · s = 1.33 × 1013 ×<br />

kg · Gy<br />

. (6.88)<br />

Bq · s<br />

Now let us return <strong>to</strong> the problem. Since the 24 Na is cleared exponentially at an<br />

effective rate λE, the amount of activity in the source organ is given by<br />

As(t) = As(0) × e −λEt , (6.89)<br />

where As(0) is the initial activity in the source.<br />

∞<br />

∞<br />

à = As(t)dt = As(0) e −λEt As(0)<br />

dt = . (6.90)<br />

0<br />

Since<br />

λE = 0.693 0.693<br />

=<br />

(TR × TB)/(TR + TB)<br />

TE<br />

0<br />

the biological half-life TB is found in International Commission on Radiological<br />

Protection (ICRP) Publication 2 <strong>to</strong> be 264 hours, and the radioactive half-life TR is<br />

15 hours, therefore<br />

à =<br />

λE<br />

10 6 Bq<br />

1.36 × 10 −5 s −1 = 7.35 × 1010 Bq · s.<br />

Now we must calculate ϕii<br />

The absorbed fractions, ϕi, in a number of target organs and tissues, for pho<strong>to</strong>ns<br />

ranging in energy from 0.01 <strong>to</strong> 4 MeV that originate in a number of different source<br />

organs and tissues, are tabulated in Appendix A of the Journal of Nuclear Medicine,<br />

Supplement No. 3, August 1969. 2 Table 6-8 shows the absorbed fractions from a<br />

pho<strong>to</strong>n emitter that is uniformly distributed throughout the body, as in the case of<br />

24 Na. The values of ϕi for the 1.369-MeV and 2.754-MeV gammas were found by<br />

interpolation between values in Table 6-8 and are listed below, <strong>to</strong>gether with i,<br />

2As the MIRD system evolved, the absorbed fraction was replaced by the specific absorbed fraction,<br />

which is discussed in the following paragraph.

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